Results 31 to 40 of about 2,355 (146)

Imidazolium salts as an alternative for anti-Leishmania drugs: Oxidative and immunomodulatory activities

Frontiers in Immunology, 2023
In this study we explored the previously established leishmanicidal activity of a complementary set of 24 imidazolium salts (IS), 1-hexadecylimidazole (C16Im) and 1-hexadecylpyridinium chloride (C16PyrCl) against Leishmania (Leishmania) amazonensis and ...
Fernanda Giesel Baldissera, Fernanda Giesel Baldissera, Tiago Fazolo, Tiago Fazolo, Matheus Brasil da Silva, Paulo Cesar de Santana Filho, Vinícius Demétrio da Silva, David Max Rivillo Perez, Joice Sandra Klitzke, Eduardo Giovanni de Oliveira Soares, Luiz Carlos Rodrigues Júnior, Luiz Carlos Rodrigues Júnior, Alessandra Peres, Alessandra Peres, Eliane Dallegrave, Kely Campos Navegantes-Lima, Marta Chagas Monteiro, Henri Stephan Schrekker, Pedro Roosevelt Torres Romão, Pedro Roosevelt Torres Romão, Pedro Roosevelt Torres Romão   +20 more
doaj   +1 more source

Subclinical Muscle Injuries in Dogs Infected with Leishmania (Leishmania) infantum chagasi [PDF]

Brazilian Journal of Veterinary Pathology, 2012
Although canine visceral leishmaniasis (CVL) has been extensively studied, muscular damage due to Leishmania (Leishmania) infantum chagasi infection remains to be fully established. The aim of this study was to describe the electromyographic and histological changes, as well as search for the presence of amastigote forms of Leishmania spp, CD3+ T ...
Gomes, Ana Amélia Domingues, Laurenti, Márcia Dalastra, Ferraro, Gisela Cristiane, de Camargo, Mauro Henrique Bueno, Costa, Denis Carvalho, Machado, Gisele Fabrino, Perri, Silvia Helena Venturoli, Marcondes, Mary   +7 more
openaire   +1 more source

Generation of Luciferase-Expressing Leishmania infantum chagasi and Assessment of Miltefosine Efficacy in Infected Hamsters through Bioimaging [PDF]

PLoS Neglected Tropical Diseases, 2015
Juliana Quero Reimão, Cristiana T Trinconi, Paulo C Cotrim   +2 more
exaly   +2 more sources

Heterogeneity of Leishmania infantum chagasi Kinetoplast DNA in Teresina (Brazil) [PDF]

The American Society of Tropical Medicine and Hygiene, 2010
Leishmania infantum chagasi is the causative agent of visceral leishmaniasis in Brazil. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis of kinetoplast DNA (kDNA) minicircles was used to evaluate genetic profiles of 48 Leishmania infantum chagasi strains from dog and human parasite cultures, fresh collected dog ...
Diego Peres, Alonso, Dorcas Lamounier, Costa, Ivete Lopes, de Mendonça, Carlos Henrique Nery, Costa, Paulo Eduardo Martins, Ribolla   +4 more
openaire   +2 more sources

Comparative Genomic Analyses of New and Old World Viscerotropic Leishmanine Parasites: Further Insights into the Origins of Visceral Leishmaniasis Agents

Microorganisms, 2022
Visceral leishmaniasis (VL), also known as kala-azar, is an anthropozoonotic disease affecting human populations on five continents. Aetiologic agents belong to the Leishmania (L.) donovani complex.
Fernando Tobias Silveira, Edivaldo Costa Sousa Junior, Rodrigo Vellasco Duarte Silvestre, Thiago Vasconcelos dos Santos, Wilfredo Sosa-Ochoa, Concepción Zúniga Valeriano, Patrícia Karla Santos Ramos, Samir Mansour Moraes Casseb, Luciana Vieira do Rêgo Lima, Marliane Batista Campos, Vania Lucia da Matta, Claudia Maria Gomes, Gabriela V. Araujo Flores, Carmen M. Sandoval Pacheco, Carlos Eduardo Corbett, Márcia Dalastra Laurenti   +15 more
doaj   +1 more source

Topical resiquimod protects against visceral infection with Leishmania infantum chagasi in mice. [PDF]

Clin Vaccine Immunol, 2014
ABSTRACTNew prevention and treatment strategies are needed for visceral leishmaniasis, particularly ones that can be deployed simply and inexpensively in areas where leishmaniasis is endemic. Synthetic molecules that activate Toll-like receptor 7 and 8 (TLR7/8) pathways have previously been demonstrated to enhance protection against cutaneous ...
Craft N, Birnbaum R, Quanquin N, Erfe MC, Quant C, Haskell J, Bruhn KW.   +6 more
europepmc   +4 more sources

Leishmania infantum ecto-nucleoside triphosphate diphosphohydrolase-2 is an apyrase involved in macrophage infection and expressed in infected dogs. [PDF]

PLoS Neglected Tropical Diseases, 2014
Visceral leishmaniasis is an important tropical disease, and Leishmania infantum chagasi (synonym of Leishmania infantum) is the main pathogenic agent of visceral leishmaniasis in the New World. Recently, ecto-nucleoside triphosphate diphosphohydrolases (
Raphael De Souza Vasconcellos, Christiane Mariotini-Moura, Rodrigo Saar Gomes, Tiago Donatelli Serafim, Rafaela de Cássia Firmino, Matheus Silva E Bastos, Felipe Freitas de Castro, Claudia Miranda de Oliveira, Lucas Borges-Pereira, Anna Cláudia Alves de Souza, Ronny Francisco de Souza, Gabriel Andres Tafur Gómez, Aimara da Costa Pinheiro, Talles Eduardo Ferreira Maciel, Abelardo Silva-Júnior, Gustavo Costa Bressan, Márcia Rogéria Almeida, Munira Muhammad Abdel Baqui, Luís Carlos Crocco Afonso, Juliana Lopes Rangel Fietto   +19 more
doaj   +1 more source

Evidência de transmissão de leishmaniose visceral por Lutzomyia cruzi no município de Jaciara, Estado de Mato Grosso, Brasil

Revista da Sociedade Brasileira de Medicina Tropical, 2011
INTRODUÇÃO: O município de Jaciara foi classificado em 2003, como área de transmissão de leishmaniose visceral em situação de surto. O trabalho objetivou determinar evidência de transmissão de Leishmania (Leishmania) infantum chagasi por Lutzomyia cruzi ...
Nanci Akemi Missawa, Márcia Aurélia Esser Veloso, Giovana Belem Moreira Lima Maciel, Érika Monteiro Michalsky, Edelberto Santos Dias   +4 more
doaj   +1 more source

Miocardite crônica em um cão naturalmente infectado com Leishmania (Leishmania) infantum chagasi: aspectos clínicos e patológicos

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2014
A leishmaniose visceral (LV) é uma doença infecciosa crônica frequentemente fatal causada pela Leishmania infantum chagasi nas Américas. A enfermidade pode acometer vários órgãos, determinando diferentes manifestações clínicas.
R.S. Mendes, T.A. Gurjão, L.M. Oliveira, V.L. Santana, W.L. Tafuri, J.R.S. Santos, A.F.M. Dantas, A.P. Souza   +7 more
doaj   +1 more source

Leishmania infantum versus Leishmania chagasi: do not forget the law of priority [PDF]

Memórias do Instituto Oswaldo Cruz, 2006
(Diptera:Psychodidae) and visceral leishmaniasis (VL) in the Ameri-cas, with particular attention to the eco-epidemiology ofdisease in Brazil. In their review, they have discussed withproperty the taxonomic position and origin of the causalagent of the disease.
openaire   +4 more sources