Results 41 to 50 of about 2,376 (150)

LXR deficiency confers increased protection against visceral Leishmania infection in mice. [PDF]

PLoS Neglected Tropical Diseases, 2010
The liver X receptors (LXRs) are a family of nuclear receptor transcription factors that are activated by oxysterols and have defined roles in both lipid metabolism and cholesterol regulation.
Kevin W Bruhn, Chaitra Marathe, Ana Cláudia Maretti-Mira, Hong Nguyen, Jacquelyn Haskell, Thu Anh Tran, Veena Vanchinathan, Upasna Gaur, Mary E Wilson, Peter Tontonoz, Noah Craft   +10 more
doaj   +1 more source

New record of preclinical diagnosis of American visceral leishmaniasis in Amazonian Brazil encourages optimizing disease control

Parasite Epidemiology and Control, 2020
The clinical-immunological spectrum of human Leishmania (L.) infantum chagasi-infection in Amazonian Brazil has recently been reviewed based on the combined use of the delayed-type hypersensitivity (DTH) and indirect fluorescence antibody test (IFAT-IgG ...
Luciana Lima, Thiago Vasconcelos-dos-Santos, Marliane Campos, Patrícia Karla Ramos, Claudia Gomes, Marcia Laurenti, Vania da Matta, Carlos Corbett, Fernando Silveira   +8 more
doaj   +1 more source

Biodistribution of meglumine antimoniate in healthy and Leishmania (Leishmania) infantum chagasi-infected BALB/c mice [PDF]

Memórias do Instituto Oswaldo Cruz, 2013
Pentavalent antimonials such as meglumine antimoniate (MA) are the primary treatments for leishmaniasis, a complex disease caused by protozoan parasites of the genus Leishmania . Despite over 70 years of clinical use, their mechanisms of action, toxicity and pharmacokinetics have not been fully elucidated.
Borborema, Samanta Etel Treiger, Osso Junior, João Alberto, Andrade Junior, Heitor Franco de, Nascimento, Nanci do   +3 more
openaire   +4 more sources

Visceral leishmaniasis and infectious hepatitis in bush dog from captivity in Brazil - Report of case/
Leishmaniose visceral e hepatite infecciosa em cachorro-vinagre mantido em cativeiro no Brasil - Relato de Caso

Semina: Ciências Agrárias, 2011
Among mammals, the canids are most often infected by Leishmania sp. This paper reports the occurrence of Leishmania (Leishmania) infantum chagasi as well as the presence of intranuclear inclusions resembling viral particles of canine adenovirus-1 in a ...
Luciano Nakazato, Valéria Dutra, Edson Moleta Colodel, Daphine Ariadne Jesus de Paula, Arleana Bom Parto Ferreira de Almeida, Valéria Régia Franco Sousa   +5 more
doaj   +1 more source

Macrophage and T-cell gene expression in a model of early infection with the protozoan Leishmania chagasi. [PDF]

PLoS Neglected Tropical Diseases, 2008
Visceral leishmaniasis is a potentially fatal infectious disease caused by the protozoan parasite Leishmania infantum/chagasi in the New World, or by L. donovani or L. infantum/chagasi in the Old World.
Nicholas A Ettinger, Mary E Wilson
doaj   +1 more source

Design of primer pairs for species-specific diagnosis of Leishmania (Leishmania) infantum chagasi using PCR [PDF]

Revista Brasileira de Parasitologia Veterinária, 2012
The objective of this study was to design and evaluate new primers for species-specific detection of L. infantum chagasi using PCR. Two combinations of primer pairs were established with the aim of obtaining specific amplification products from the L. infantum chagasi 18S rRNA gene.
Osvaldo José, da Silveira Neto, Sabrina Castilho, Duarte, Hérika Xavier, da Costa, Guido Fontgalland Coelho, Linhares   +3 more
openaire   +2 more sources

Complete conservation of an immunogenic gene (lcr1) in Leishmania infantum and Leishmania chagasi isolated from Iran, Spain and Brazi [PDF]

Journal of Vector Borne Diseases, 2010
Background & objectives: Kala-azar is the visceral and most severe form of leishmaniasis thatleads to death if untreated. The causative agents of visceral leishmaniasis (VL) are members ofLeishmania (L.) donovani complex which includes L.
H. Mahmoudzadeh-Niknam , F. Abrishami , M. Doroudian , M. Moradi , M.H. Alimohammadian , P. Parvizi
doaj  

Comparative analysis of biological aspects of Leishmania infantum strains.

PLoS ONE, 2020
Leishmania infantum infantum (LII) is one of the species that causes visceral leishmaniasis (VL) in the Old World, while L. infantum chagasi (LIC) is present in the New World.
Taiana Ferreira-Paes, Karen Dos Santos Charret, Merienny Ramos da Silva Ribeiro, Raquel Ferreira Rodrigues, Leonor Laura Leon   +4 more
doaj   +1 more source

THE SERO-CONVERSION AND EVALUATION OF RENAL ALTERATIONS IN DOGS INFECTED BY Leishmania (Infantum) chagasi [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2013
This study investigated the sero-conversion period in which dogs from endemic areas test positive for visceral leishmaniasis (VL) as well as the early post-infection period in which renal alterations are observed. Dogs that were initially negative for Canine Visceral Leishmaniasis (CVL) were clinically evaluated every three months by serological ...
Alves, Georgia Brenda Barros, Silva, Lucilene dos Santos, Batista, Joilson Ferreira, Campos, Ângela Piauilino, Prianti, Maria das Graças, Costa, Francisco Assis Lima   +5 more
openaire   +5 more sources

Autochthonous case of Canine Visceral Leishmaniasis in a non-endemic area in Minas Gerais, Brazil

Pesquisa Veterinária Brasileira
: Visceral Leishmaniasis by Leishmania infantum chagasi is an endemic zoonosis present in many areas of Brazil. This parasite needs reservoirs for maintenance of the infection and the presence of dogs in urban areas is a key factor for the spread of ...
Mariana Teixeira de Faria, Fernando S. Barbosa, Rafael G. Teixeira-Neto, Guilherme R.G. Pinheiro, Marianna N. Manhani, Andreza P. Marcelino, José Ronaldo Barbosa, Gilberto Fontes   +7 more
doaj   +1 more source