Results 61 to 70 of about 2,355 (146)

Antiprotozoal action of synthetic cinnamic acid analogs

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION Leishmaniasis, Chagas disease, and malaria cause morbidity globally. The drugs currently used for treatment have limitations. Activity of cinnamic acid analogs against Leishmania spp., Trypanosoma cruzi, and Plasmodium falciparum was ...
Ana Paula de Azevedo dos Santos, Saara Nery Fialho, Daniel Sol Sol de Medeiros, Ana Fidelina Gómez Garay, Jorge Alfonso Ruiz Diaz, Maria Celeste Vega Gómez, Carolina Bioni Garcia Teles, Leonardo de Azevedo Calderon   +7 more
doaj   +1 more source

Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge.

PLoS ONE, 2016
Dogs represent the most important domestic reservoir of L. chagasi (syn. L. infantum). A vaccine against canine visceral leishmaniasis (CVL) would be an important tool for decreasing the anxiety related to possible L.
Lucilene Aparecida Resende, Rodrigo Dian de Oliveira Aguiar-Soares, Henrique Gama-Ker, Bruno Mendes Roatt, Ludmila Zanandreis de Mendonça, Marina Luiza Rodrigues Alves, Denise da Silveira-Lemos, Rodrigo Corrêa-Oliveira, Olindo Assis Martins-Filho, Márcio Sobreira Silva Araújo, Ricardo Toshio Fujiwara, Nelder Figueiredo Gontijo, Alexandre Barbosa Reis, Rodolfo Cordeiro Giunchetti   +13 more
doaj   +1 more source

Molecular characterization of Trypanosoma cruzi and Leishmania spp. coinfection in mammals of Venezuelan coendemic areas

Journal of Vector Borne Diseases, 2019
Background & objectives: Trypanosoma cruzi and Leishmania spp. are protozoans that cause American trypanosomiasis and leishmaniasis, respectively. In endemic foci where both diseases coincide, coinfection can occur.
M Viettri, L Herrera, C M Aguilar, A Morocoima, J Reyes, M Lares, D Lozano-Arias, R García-Alzate, T Chacón, M D Feliciangeli, E Ferrer   +10 more
doaj   +1 more source

Leishmania infantum chagasi: A genome-based approach to identification of excreted/secreted proteins [PDF]

Experimental Parasitology, 2010
The parasitic protozoan, Leishmania, survives in harsh environments within its mammalian and sand fly hosts. Secreted proteins likely play critical roles in the parasite's interactions with its environment. As a preliminary identification of the spectrum of potential excreted/secreted (ES) proteins of Leishmania infantum chagasi (Lic), a causative ...
Sruti, DebRoy, Alexandra B, Keenan, Norikiyo, Ueno, Selma M B, Jeronimo, John E, Donelson, Mary E, Wilson   +5 more
openaire   +2 more sources

Molecular and serological detection of tick-borne pathogens in dogs from an area endemic for Leishmania infantumin Mato Grosso do Sul, Brazil

Revista Brasileira de Parasitologia Veterinária
Tick-borne pathogens affect a wide range of vertebrate hosts. To identify tick-borne pathogens among dogs from Campo Grande, MS, Brazil testing seropositive for Leishmania infantum (syn. L.
Keyla Carstens Marques de Sousa, Marcos Rogério André, Heitor Miraglia Herrera, Gisele Braziliano de Andrade, Marcia Mariza Gomes Jusi, Luciana Ladislau dos Santos, Wanessa Teixeira Gomes Barreto, Rosangela Zacarias Machado, Gilson Pereira de Oliveira   +8 more
doaj   +1 more source

Sex in Immune Cells and Parasitic Diseases — A Complex Relationship

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker, Charlotte Sophie Hansen, Hanna Lotter   +2 more
wiley   +1 more source

Diagnostic Challenges in Visceral Leishmaniasis in a 17‐Month‐Old Female: A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Visceral leishmaniasis is an uncommon infectious disease. In this report, we present a case of VL in a 17‐month‐old child who presented with a fever and splenomegaly. After the patient failed to respond to several courses of antibiotics, a bone marrow aspirate confirmed the definitive diagnosis of VL, which was successfully treated with ...
Ahmed Sheikh Sobeh, Manal Soufan, Tasneem Sarakbi, Alaa Jaddouh, Feras Alharroush   +4 more
wiley   +1 more source

Antileishmanial Activities of Carvacrol Nanoencapsulate in Biopolymeric Nanoparticles

Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.
The study obtained biopolymeric nanoparticles containing carvacrol (NPCar) and evaluated their anti‐leishmanial activity. NPCar obtained presented physicochemical characteristics due to its ideal nanometric size and zeta potential, and low polydispersity index.
Joyce Cordeiro Borges, Anne Beatriz Cunha Barros, Leonardo Lima Cardoso, Tatjana de Lima Souza Keesen, Luís André de Almeida Campos, Isabella Macário Ferro Cavalcanti, Elisângela Afonso de Moura Kretzschmar   +6 more
wiley   +1 more source

Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae)

Journal of Venomous Animals and Toxins including Tropical Diseases
Background: Visceral leishmaniasis is a complex neglected tropical disease caused by Leishmania donovani complex. Its current treatment reveals strong limitations, especially high toxicity.
Thais A. da Costa-Silva, Geanne A. Alves Conserva, Andrés J. Galisteo Jr, Andre G. Tempone, João Henrique G. Lago   +4 more
doaj   +1 more source

First occurrence of an autochthonous canine case of Leishmania (Leishmania) infantum chagasi in the municipality of Campinas, State of São Paulo, Brazil

Revista do Instituto de Medicina Tropical de São Paulo, 2011
An autochthonous case of visceral leishmaniasis is reported in a dog (Canis familiaris) as an apparently natural infection in a non-endemic area. DNA obtained from spleen and liver samples produced the expected fragment in a Leishmania-specific rDNA ...
Elisa San Martin Mouriz Savani, Douglas Presotto, Thais Roberto, Maria Cecília Gibrail de Oliveira Camargo, Sandra Regina Nicoletti D'auria, Débora Veiga Sacramento   +5 more
doaj   +1 more source