Results 71 to 80 of about 2,376 (150)

Antileishmanial Activities of Carvacrol Nanoencapsulate in Biopolymeric Nanoparticles

Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.
The study obtained biopolymeric nanoparticles containing carvacrol (NPCar) and evaluated their anti‐leishmanial activity. NPCar obtained presented physicochemical characteristics due to its ideal nanometric size and zeta potential, and low polydispersity index.
Joyce Cordeiro Borges, Anne Beatriz Cunha Barros, Leonardo Lima Cardoso, Tatjana de Lima Souza Keesen, Luís André de Almeida Campos, Isabella Macário Ferro Cavalcanti, Elisângela Afonso de Moura Kretzschmar   +6 more
wiley   +1 more source

First occurrence of an autochthonous canine case of Leishmania (Leishmania) infantum chagasi in the municipality of Campinas, State of São Paulo, Brazil

Revista do Instituto de Medicina Tropical de São Paulo, 2011
An autochthonous case of visceral leishmaniasis is reported in a dog (Canis familiaris) as an apparently natural infection in a non-endemic area. DNA obtained from spleen and liver samples produced the expected fragment in a Leishmania-specific rDNA ...
Elisa San Martin Mouriz Savani, Douglas Presotto, Thais Roberto, Maria Cecília Gibrail de Oliveira Camargo, Sandra Regina Nicoletti D'auria, Débora Veiga Sacramento   +5 more
doaj   +1 more source

Therapeutic Effect of Barberry (Berberis vulgaris) Root Extract on Experimental Cutaneous Leishmaniosis in a BALB/c Mouse Model

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
Barberry (Berberis vulgaris) root extract shows potential in treating cutaneous leishmaniasis caused by Leishmania major. In a BALB/c mouse model, treatment significantly reduced wound size and parasite load while enhancing inflammatory markers IL‐1 and IL‐6. These results highlight barberry's therapeutic promise against leishmaniasis.
Sadegh Shirian, Morteza Norouzi Cholcheh, Saeed Habibian Dehkordi, Behnam Bakhtiari Moghadam   +3 more
wiley   +1 more source

Estudo fitoquímico e atividades leishmanicida, anticolinestarásica e antioxidante de extratos de Annona glabra L. (araticum panã)

Revista de Ciências Farmacêuticas Básica e Aplicada, 2015
O objetivo deste estudo foi investigar as principais classes de compostos químicos presentes em Annona grabra L. (Araticum panã), e avaliar o seu potencial biológico analisando suas atividades antioxidante, antiacetilcolinesterase e leishmanicida.
Antonio Adailson de Sousa Silva, Joana Barros Alexandre, Larissa Guerra Vieira, Suliane Praciano Rodrigues, Maria José Cajazeiras Falcão, Selene Maia Morais   +5 more
doaj   +2 more sources

IL‐12 and IFN‐γ in Response to Leishmania Infantum Antigens in Felines From an Endemic Area for Visceral Leishmaniasis

Parasite Immunology, Volume 47, Issue 8, August 2025.
ABSTRACT Visceral leishmaniasis is a potentially fatal zoonosis with an increasing incidence. Most infected felines present the disease in its subclinical form and demonstrate greater resistance to parasitemia than dogs. However, the role of cellular immunity in felines is still poorly understood. This study measured serum levels of interleukin (IL)‐12
João Victor Lé Lode, Lucas Takeshi Siqueira Ito, Gisele Mitsue Umino, Valéria Marçal Felix de Lima   +3 more
wiley   +1 more source

Integration of Machine Learning‐QSAR and Polypharmacology in Drug Discovery for Leishmaniasis Using Natural and Repurposed Compounds

ChemistrySelect, Volume 10, Issue 21, June 4, 2025.
Leishmaniasis affects over 1 billion people worldwide, with current treatments limited by toxicity and efficacy. This study used machine learning (ML), QSAR, and polypharmacology to identify potential drug candidates, analyzing 12,072 compounds with random forest and XGBoost models.
Laís Salvador do Amaral, Amiel Artur Morais, Alexandre de Fátima Cobre, Raul Edison Luna Lazo, Dile Pontarolo Stremel, Jaqueline Carneiro, Luana Mota Ferreira, Roberto Pontarolo   +7 more
wiley   +1 more source

Expression of leukosialin (CD43) defines a major intrahepatic T cell subset associated with protective responses in visceral leishmaniasis

Parasites & Vectors, 2015
Background Leishmaniasis is a neglected vector-borne tropical disease caused by Leishmania protozoa that are transmitted to mammalian hosts by infected sand flies.
Dirlei Nico, Naiara Maran, Leonardo Santos, Erivan Schnaider Ramos-Junior, Natália Rodrigues Mantuano, Joseane Lima Prado Coutinho, Andre Macedo Vale, Celio Geraldo Freire-de-Lima, Adriane Todeschini, Juliany Cola Fernandes Rodrigues, Clarisa Beatriz Palatnik-de-Sousa, Alexandre Morrot   +11 more
doaj   +1 more source

Impact of leishmaniasis on public health

Journal of Venomous Animals and Toxins including Tropical Diseases, 2006
Leishmaniasis is a parasitic zoonosis caused by protozoans of the genus Leishmania transmitted by insects known as phlebotomines, which are found in wild or urban environments.
L. B Camargo, H. Langoni
doaj   +1 more source

Cutaneous Leishmaniasis Mimicking a Nasal Tumor: A Case Report

Case Reports in Infectious Diseases, Volume 2025, Issue 1, 2025.
Leishmaniasis is a disease caused by Leishmania protozoa that is transmitted to the patient by sand flies. Depending on the Leishmania species, the disease can present with cutaneous, mucosal, or multiorgan involvement. Cutaneous leishmaniasis can present with diverse clinical manifestations mimicking other diseases.
Maryam Hekmat, Mohammad Reza Namazi, Amir Hossein Najibi, Babak Shirazi Yeganeh, Negin Fazelzadeh Haghighi, Larry M. Bush   +5 more
wiley   +1 more source

Mucocutaneous Leishmaniasis With Oral Involvement: A Case Report

Case Reports in Dentistry, Volume 2025, Issue 1, 2025.
The primary objective of the present study is the retrospective analysis of a clinical case of oral leishmaniasis treated at Parma Hospital and a review of the literature on mucosal leishmaniasis (ML) with oral cavity involvement. We report the case of a patient diagnosed in 2017 with mucocutaneous leishmaniasis who was referred to our clinic due to ...
Pierpaolo De Francesco, Paolo Vescovi, Claudio Feliciani, Roberta Iaria, Luigi Corcione, Ilaria Giovannacci, Vlaho Brailo   +6 more
wiley   +1 more source