Results 81 to 90 of about 2,355 (146)

Performance of Extracellular Vesicles From Leishmania (Leishmania) infantum for Serological Diagnosis of Human and Canine Visceral Leishmaniasis

Journal of Parasitology Research, Volume 2025, Issue 1, 2025.
Visceral leishmaniasis (VL) is a zoonotic disease in which dogs are the main reservoirs. Until now, the serological tests do not present satisfactory sensitivity for diagnosis of these hosts. One of the functions of extracellular vesicles (EVs) is related to immunological host response.
Allecineia Bispo da Cruz, Francieli Marinho Carneiro, Noemi Nosomi Taniwaki, Gislene Mitsue Namiyama, Débora Oliveira dos Santos, Katia Gomes Castellão, Isabelle Martins Ribeiro Ferreira, Roberto Mitsuyoshi Hiramoto, Vera Lucia Pereira-Chioccola, Bernard Marchand   +9 more
wiley   +1 more source

Stage-Specific Pathways of Leishmania infantum chagasi Entry and Phagosome Maturation in Macrophages

PLoS ONE, 2011
The life stages of Leishmania spp. include the infectious promastigote and the replicative intracellular amastigote. Each stage is phagocytosed by macrophages during the parasite life cycle. We previously showed that caveolae, a subset of cholesterol-rich membrane lipid rafts, facilitate uptake and intracellular survival of virulent promastigotes by ...
Nilda E Rodríguez, Upasna Gaur Dixit, Lee-Ann H Allen, Mary E Wilson   +3 more
openaire   +4 more sources

Effectiveness of liposomal buparvaquone in an experimental hamster model of Leishmania (L.) infantum chagasi

Experimental Parasitology, 2012
The objective of this study was to develop a novel liposomal formulation, containing phosphatidylserine (PS), of buparvaquone (BPQ) and to evaluate its in vivo effectiveness in Leishmania (L.) infantum chagasi-infected hamsters. The activity of BPQ was evaluated against both the promastigote forms of different Leishmania species and the intracellular ...
Reimão, Juliana Q., Colombo, Fábio A., Pereira-Chioccola, Vera L., Tempone, André G.   +3 more
openaire   +2 more sources

Infecção natural de Lutzomyia (Lutzomyia) longipalpis (Diptera: Psychodidae) por Leishmania infantum chagasi em flebotomíneos capturados no município de Janaúba, Estado de Minas Gerais, Brasil

Revista da Sociedade Brasileira de Medicina Tropical, 2011
INTRODUÇÃO: A leishmaniose visceral tem sido notificada em quase todos os estados do Brasil, e principalmente no norte de Minas Gerais, onde a doença é endêmica. Este estudo visou detectar a infecção natural de Lutzomyia longipalpis e identificar através
Érika Monteiro Michalsky, Karla de Sena Guedes, Fabiana de Oliveira Lara e Silva, João Carlos França-Silva, Consuelo Latorre Fortes Dias, Ricardo Andrade Barata, Edelberto Santos Dias   +6 more
doaj   +1 more source

The gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil. [PDF]

Mem Inst Oswaldo Cruz, 2021
Lemos-Silva T, Telleria EL, Traub-Csekö YM.   +2 more
europepmc   +1 more source

Immunobiology of visceral leishmaniasis

Frontiers in Immunology, 2012
Visceral leishmaniasis (VL), commonly known as kala-azar, is caused by Leishmania donovani and Leishmania infantum (Leishmania chagasi in the Americas). These Leishmania species infect macrophages throughout the viscera, and parasites are typically found
Susanne eNylén, Rajiv eKumar
doaj   +1 more source

Identification of Leishmania species by high-resolution DNA dissociation in cases of American cutaneous leishmaniasis, [PDF]

Anais Brasileiros de Dermatologia
Background American cutaneous leishmaniasis is an infectious dermatosis caused by protozoa of the genus Leishmania, which comprises a broad spectrum of clinical manifestations depending on the parasite species involved in the infections and the ...
John Verrinder Veasey, Ricardo Andrade Zampieri, Rute Facchini Lellis, Thaís Helena Proença de Freitas, Lucile Maria Floeter Winter   +4 more
doaj   +2 more sources

Cross-protective effect of a combined L5 plus L3 Leishmania major ribosomal protein based vaccine combined with a Th1 adjuvant in murine cutaneous and visceral leishmaniasis

Parasites & Vectors, 2014
Background Two Leishmania major ribosomal proteins L3 (LmL3) and L5 (LmL5) have been described as protective molecules against cutaneous leishmaniasis due to infection with L.
Laura Ramirez, Laura Corvo, Mariana C Duarte, Miguel A Chávez-Fumagalli, Diogo G Valadares, Diego M Santos, Camila I de Oliveira, Marta R Escutia, Carlos Alonso, Pedro Bonay, Carlos AP Tavares, Eduardo AF Coelho, Manuel Soto   +12 more
doaj   +1 more source

Expression of a rK39 homologue from an Iranian Leishmania infantum isolate in Leishmania tarentolae for serodiagnosis of visceral leishmaniasis

Parasites & Vectors, 2019
Background Kinesin-related gene diversity among strains and species of Leishmania may impact the sensitivity and specificity of serodiagnostic tests for visceral leishmaniasis (VL).
Zahra Rezaei, Nick Van Reet, Gholamreza Pouladfar, Vera Kühne, Amin Ramezani, Bahador Sarkari, Bahman Pourabbas, Philippe Büscher   +7 more
doaj   +1 more source

Unusual Clinical Manifestations of Leishmania (L.) infantum chagasi in an HIV-coinfected Patient and the Relevance of ITS1-PCR-RFLP: A Case Report

Iranian Journal of Parasitology, 2018
Patients coinfected with Leishmania/HIV can develop atypical forms of visceral leishmaniasis (VL), making it indispensable to identify the etiological agent. We are presenting a postmortemspecie definition by ITS1-PCR-RFLP in a larynx tissue of a patient
De Godoy NATALIA SOUZA DE, Aiello VERA DEMARCHI, de Souza REGINA MAIA, Okay THELMA, Braz LUCIA MARIA ALMEIDA   +4 more
doaj