The Antileishmanial Potential of C-3 Functionalized Isobenzofuranones against Leishmania (Leishmania) Infantum Chagasi [PDF]
Molecules, 2015 Leishmaniases are diseases caused by protozoan parasites of the genus Leishmania. Clinically, leishmaniases range from cutaneous to visceral forms, with estimated global incidences of 1.2 and 0.4 million cases per year, respectively. The treatment of these diseases relies on multiple parenteral injections with pentavalent antimonials or amphotericin B.
Christiane Mariotini-Moura +2 more
exaly +6 more sources
A novel A2 allele found in Leishmania (Leishmania) infantum chagasi Novo alelo do gene A2 descrito em Leishmania (Leishmania) infantum chagasi [PDF]
Revista Brasileira de Parasitologia Veterinária, 2011 Visceral leishmaniasis (VL) is a widely spread zoonotic disease. In Brazil the disease is caused by Leishmania (Leishmania) infantum chagasi. Peridomestic sandflies acquire the etiological agent by feeding on blood of infected reservoir animals, such as ...
Trícia Maria Ferreira de Sousa Oliveira +7 more
doaj +8 more sources
Hemostatic assessment of dogs associated with hepatic parasite load of Leishmania infantum chagasi [PDF]
Brazilian Journal of Veterinary Parasitology, 2016 Leishmania infantum chagasi liver parasite load was compared to hemostatic abnormalities, as well as to clinical, laboratorial, and histopathological findings in dogs with visceral leishmaniasis. The liver parasite load of 30 dogs L.
Arleana Do Bom Parto Ferreira De Almeida +2 more
exaly +6 more sources
The transmission of
Parasites & Vectors, 2012 Background Sandflies are vectors of Leishmania, the causative agent of leishmaniasis in mammalian hosts, including humans. The protozoan parasite is transmitted by the sandfly bite during salivation that occurs at the moment of blood feeding.
Secundino Nagila FC +5 more
doaj +3 more sources
Revista da Sociedade Brasileira de Medicina Tropical, 2010 INTRODUÇÃO: Leishmaniose visceral é uma zoonose que acomete diversos mamíferos tendo os canídeos domésticos como principais reservatórios em ambiente urbano.
Nely Pinheiro Souza +6 more
doaj +2 more sources
Use of a Recombinant Cysteine Proteinase from Leishmania (Leishmania) infantum chagasi for the Immunotherapy of Canine Visceral Leishmaniasis [PDF]
PLoS Neglected Tropical Diseases, 2014 A recombinant cysteine proteinase from Leishmania (Leishmania) infantum chagasi (rLdccys1) was previously shown to induce protective immune responses against murine and canine visceral leishmaniasis. These findings encouraged us to use rLdccys1 in the immunotherapy of naturally infected dogs from Teresina, Piauí, a region of high incidence of visceral ...
Lucilene Dos Santos Silva +2 more
exaly +6 more sources
Leishmania (infantum) chagasi in canine urinary sediment [PDF]
Revista Brasileira de Parasitologia Veterinária, 2015 Canine visceral leishmaniasis (CVL) is difficult to diagnosis, mainly due to the presence of asymptomatic animals, the diversity of clinical symptoms and the difficulty in obtaining diagnostic evidence of high sensitivity and specificity.
Ivete Lopes de Mendonça +2 more
doaj +3 more sources
Ultrastructural Analysis of Leishmania infantum chagasi Promastigotes Forms Treated In Vitro with Usnic Acid [PDF]
The Scientific World Journal, 2015 Leishmaniasis is considered by the World Health Organization as one of the infectious parasitic diseases endemic of great relevance and a global public health problem.
João S. B. da Luz +8 more
doaj +2 more sources
Evaluation of the Cutaneous Immunological Milieu Before and After Treatment With Meglumine Antimoniate in Dogs Naturally Affected by Leishmaniosis due to Leishmania infantum. [PDF]
Vet DermatolBackground: Canine leishmaniosis (CanL) is a zoonotic disease of variable severity. The typical immune response is driven by an exaggerated humoral immune response. Protective immunity is mediated by pro‐inflammatory cytokines that enhance macrophage leishmanicidal activity. Objective: To evaluate the cutaneous and the systemic immune responses as well
Platenik M +5 more
europepmc +2 more sources
Cortisol Regulates PD-1 and IL-12 in Canine Leishmaniasis. [PDF]
Parasite ImmunolABSTRACT Canine visceral leishmaniasis (CanL) is a tropical zoonosis caused by Brazil's protozoan Leishmania (L.) infantum. Disorders in the hypothalamic–pituitary–adrenal (HPA) axis have been reported in human and experimental visceral leishmaniasis, but not yet in canine leishmaniasis.
Ito LTS +6 more
europepmc +2 more sources