Results 31 to 40 of about 14,096,336 (162)
Three isolates of Leishmania were recovered from five of 27 specimens of the rodent Proechimys iheringi denigratus Moojen captured near Três Braços in the Atlantic Forest region of Bahia, Brazil.
Air C. Barretto +7 more
doaj +3 more sources
Antigenic extracts from five Leishmania stocks were used to vaccinate C57BL/10 mice. The Leishvacin® and PH8 monovalent vaccine yielded the highest IFN-gamma levels in the supernatants of spleen cell culture from vaccinated animals.
Wilson Mayrink +6 more
doaj +1 more source
Drosophila Model of Leishmania amazonensis Infection [PDF]
This protocol describes how to generate and harvest antibody-free L. amazonensis amastigotes, and how to infect adult Drosophila melanogaster with these parasites.
Silverman, Neal, Okuda, Kendi
core +1 more source
Visceral leishmaniasis (VL) is mainly caused by Leishmania (Leishmania) donovani and Leishmania (L.) infantum; however, other Leishmania species have been associated with VL.
Litvoc, Marcelo Nobrega +9 more
core +1 more source
CBA mouse macrophages control Leishmania major infection yet are permissive to Leishmania amazonensis. Few studies have been conducted to assess the role played by autophagy in Leishmania infection.
Beatriz R. S. Dias +11 more
doaj +1 more source
Antileishmanial activity of extracts from Libidibia ferrea: development of in vitro and in vivo tests [PDF]
Treatment of cutaneous leishmaniasis (CL) is difficult due to the scarce number of drugs able to eliminate completely the intracellular form of the parasite.
Claudia Dantas COMANDOLLI-WYREPKOWSKI +9 more
doaj +2 more sources
Distinct Macrophage Fates after in vitro Infection with Different Species of Leishmania: Induction of Apoptosis by Leishmania (Leishmania) amazonensis, but Not by Leishmania (Viannia) guyanensis. [PDF]
Leishmania is an intracellular parasite in vertebrate hosts, including man. During infection, amastigotes replicate inside macrophages and are transmitted to healthy cells, leading to amplification of the infection.
Jarina Pena DaMata +6 more
doaj +1 more source
BackgroundLeishmaniasis is a neglected arthropod-borne disease that affects millions of people worldwide. Successful Leishmania infections require the mitigation of immune cell functions leading to parasite survival and proliferation.
Rafael Tiburcio +17 more
doaj +1 more source
Desenvolvimento de um teste colorimétrico para triagem da atividade leishmanicida de compostos utilizando Leishmania amazonensis expressando a enzima beta-galactosidase [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Programa de Pós-graduação em Biotecnologia e Biociências, Florianópolis, 2013No presente trabalho transfectamos uma cepa de Leishmania amazonensis com um plasmídeo contendo o gene da ...
Tonini, Maiko Luis
core
Systemic treatment of cutaneous leishmaniasis: A systematic review and meta‐analysis
This systematic review and meta‐analysis assessed systemic treatments for cutaneous leishmaniasis across 83 studies and 4603 patients. Treatment efficacies of meglumine antimoniate, miltefosine, azoles, pentamidine, and liposomal amphotericin B varied by region and species. Miltefosine showed consistent evidence across multiple settings.
Maximilian Egg +10 more
wiley +1 more source

