Results 31 to 40 of about 8,781 (205)

Study of the differentially abundant proteins among Leishmania amazonensis, L. braziliensis, and L. infantum

open access: yesPLOS ONE, 2020
Leishmaniasis has been considered as emerging and re-emerging disease, and its increasing global incidence has raised concerns. The great clinical diversity of the disease is mainly determined by the species. In several American countries, tegumentary leishmaniasis (TL) is associated with both Leishmania amazonensis and L.
Bruna Soares de Souza Lima   +7 more
openaire   +4 more sources

Leishmania (L.) amazonensis-induced inhibition of nitric oxide synthesis in host macrophages [PDF]

open access: yesMicrobes and Infection, 2002
Inhibition of lipopolysaccharide (LPS)-induced nitric oxide (NO) production was demonstrated in J774-G8 macrophages infected with Leishmania (L.) amazonensis promastigotes. The downmodulation of NO production observed in infected and LPS-stimulated J774-G8 cells correlated with a reduction in inducible nitric oxide synthase (iNOS) activity.
Filomena M Perrella, Balestieri   +5 more
openaire   +2 more sources

The diverse and dynamic nature of Leishmania parasitophorous vacuoles studied by multidimensional imaging. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2012
An important area in the cell biology of intracellular parasitism is the customization of parasitophorous vacuoles (PVs) by prokaryotic or eukaryotic intracellular microorganisms.
Fernando Real, Renato A Mortara
doaj   +1 more source

The role of surface glycoconjugates in Leishmania midgut attachment examined by competitive binding assays and experimental development in sand flies [PDF]

open access: yes, 2013
SUMMARY Binding of promastigotes to the sand fly midgut epithelium is regarded as an essential part of the Leishmania life cycle in the vector. Among Leishmania surface molecules putatively involved in attachment to the sand fly midgut, two GPI-anchored ...
Jecna, Lucie   +13 more
core   +1 more source

Experimental transmission of Leishmania (Leishmania) amazonensis to immunosuppressed mice through the bite of Lutzomyia longipalpis (Diptera: Psychodidae) results in cutaneous leishmaniasis

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2021
Lutzomyia longipalpis is the natural vector of Leishmania (Leishmania) infantum, but it is also permissive for several Leishmania species that are related to cutaneous leishmaniasis (CL). Maranhao State (Northeast of Brazil) is endemic for CL and has the
Rosa Cristina Ribeiro da Silva   +5 more
doaj   +1 more source

Fusion between Leishmania amazonensis and Leishmania major parasitophorous vacuoles: live imaging of coinfected macrophages. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2010
Protozoan parasites of the genus Leishmania alternate between flagellated, elongated extracellular promastigotes found in insect vectors, and round-shaped amastigotes enclosed in phagolysosome-like Parasitophorous Vacuoles (PVs) of infected mammalian ...
Fernando Real   +2 more
doaj   +1 more source

Leukocyte Behavior in Mesenteric Microcirculation upon Experimental By Leishmania Spp. in BALB/c Mice

open access: yesIranian Journal of Parasitology, 2021
Background: We aimed to determine the cellular recruitment (leukocyte rolling and adhesion) by which the Leishmania (Viannia) braziliensis, L. (Leishmania) amazonensis, and L. (Leishmania) major species in the mesenteric microcirculation of BALB/c mice.
Herintha Coeto Neitzke-Abreu   +9 more
doaj  

Immune responses induced by a Leishmania (Leishmania) amazonensis recombinant antigen in mice and lymphocytes from vaccinated subjects

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1997
In the search for Leishmania recombinant antigens that can be used as a vaccine against American Cutaneous Leishmaniasis, we identified a Leishmania (Leishmania) amazonensis recombinant protein of 33 kD (Larp33) which is recognized by antibodies and ...
Ana Paula FERNANDES   +10 more
doaj   +1 more source

In vitro leishmanicidal effect of Yangambin and Epi-yangambin lignans isolated from Ocotea fasciculata (Nees) Mez

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionYangambin and epi-yangambin are the main lignans found in Louro-de-Cheiro [Ocotea fasciculata (Nees) Mez], a tree native to the Atlantic forests of northeastern Brazil whose leaves and bark are widely used in folk medicine.
Jéssica Rebouças-Silva   +7 more
doaj   +1 more source

Leishmania (L.) amazonensis peptidase activities inside the living cells and in their lysates

open access: yesMolecular and Biochemical Parasitology, 2012
In this study we investigated the peptidase activity in Leishmania (L.) amazonensis live amastigote by confocal microscopy using peptidyl-MCA as substrates, the hydrolysis of which releases the MCA fluorophore inside the cells. Cell pre-treatment with peptidase inhibitors indicated the presence of cysteine and serine peptidases.
Caroselli, Elide E.   +6 more
openaire   +2 more sources

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