The emergence of drug-resistant Leishmania species is a significant problem in several countries. A comparative proteomic analysis of antimony-susceptible and antimony-resistant Leishmania braziliensis (LbSbR) and Leishmania infantum chagasi (LcSbR) lines was carried out using two-dimensional gel electrophoresis (2-DE) followed by mass spectrometry (LC/
Silvane Maria Fonseca Murta
exaly +3 more sources
Visceral leishmaniasis with cutaneous involvement caused by Leishmania infantum-chagasi
We report the case of a 66 year-old woman who presented nodular skin lesions on her back and upper extremities. Biopsy revealed amastigotes that were identified as Leishmania infantum-chagasi by PCR.
Mohammed Raja +1 more
doaj +3 more sources
Nephrin gene expression in chronic kidney disease of dogs with Leishmania (Leishmania) infantum chagasi. [PDF]
Torres Mde M +4 more
europepmc +5 more sources
Heterogeneities in leishmania infantum infection : using skin parasite burdens to identify highly infectious dogs [PDF]
Background: The relationships between heterogeneities in host infection and infectiousness (transmission to arthropod vectors) can provide important insights for disease management.
A Mohammadiha +56 more
core +24 more sources
Assessment of Leishmania exposure in blood donors from a non-endemic urban area: A study in São Paulo. [PDF]
Abstract Background and Objectives According to the World Health Organization, more than 1 billion people are at risk of leishmaniasis in over 89 countries. Environmental changes such as deforestation, urban expansion and climate change facilitate the spread of sand fly vectors and reservoirs, increasing disease transmission.
de Lima IS +14 more
europepmc +2 more sources
Cortisol Regulates PD-1 and IL-12 in Canine Leishmaniasis. [PDF]
ABSTRACT Canine visceral leishmaniasis (CanL) is a tropical zoonosis caused by Brazil's protozoan Leishmania (L.) infantum. Disorders in the hypothalamic–pituitary–adrenal (HPA) axis have been reported in human and experimental visceral leishmaniasis, but not yet in canine leishmaniasis.
Ito LTS +6 more
europepmc +2 more sources
Reproduction of Leishmania (Leishmania ) infantum chagasi in conditioned cell culture growth medium [PDF]
Leishmanias can be produced by inoculation in conditioned McCoy cell culture growth medium (CGM). Leishmania (Leishmania) infantum chagasi (100 parasites) grown in NNN medium was inoculated in 2.5 mL CGM, kept in plates (24 wells) and its multiplication was observed for five days (120 hours).
Nogueira, Yeda L., Galati, Eunice A.B.
openaire +6 more sources
Cutaneous Leishmaniasis Mimicking a Nasal Tumor: A Case Report. [PDF]
Leishmaniasis is a disease caused by Leishmania protozoa that is transmitted to the patient by sand flies. Depending on the Leishmania species, the disease can present with cutaneous, mucosal, or multiorgan involvement. Cutaneous leishmaniasis can present with diverse clinical manifestations mimicking other diseases.
Hekmat M +4 more
europepmc +2 more sources
In this study we explored the previously established leishmanicidal activity of a complementary set of 24 imidazolium salts (IS), 1-hexadecylimidazole (C16Im) and 1-hexadecylpyridinium chloride (C16PyrCl) against Leishmania (Leishmania) amazonensis and ...
Fernanda Giesel Baldissera +20 more
doaj +1 more source
IL-12 and IFN-γ in Response to Leishmania Infantum Antigens in Felines From an Endemic Area for Visceral Leishmaniasis. [PDF]
ABSTRACT Visceral leishmaniasis is a potentially fatal zoonosis with an increasing incidence. Most infected felines present the disease in its subclinical form and demonstrate greater resistance to parasitemia than dogs. However, the role of cellular immunity in felines is still poorly understood. This study measured serum levels of interleukin (IL)‐12
Lode JVL +3 more
europepmc +2 more sources

