In Vitro Screening Test Using Leishmania Promastigotes Stably Expressing mCherry Protein [PDF]
, 2014 Transgenic Leishmania major and Leishmania donovani axenic promastigotes constitutively expressing mCherry were used for in vitro antileishmanial drug screening. This method requires minimal sample manipulation and can be easily adapted to automatic drug
Miguel A. Morales, Vacchina, Paola
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Parasites & Vectors, 2012 Background Sandflies are vectors of Leishmania, the causative agent of leishmaniasis in mammalian hosts, including humans. The protozoan parasite is transmitted by the sandfly bite during salivation that occurs at the moment of blood feeding.
Secundino Nagila FC +5 more
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Biodistribution of meglumine antimoniate in healthy and Leishmania (Leishmania) infantum chagasi-infected BALB/c mice [PDF]
Memórias do Instituto Oswaldo Cruz, 2013 Pentavalent antimonials such as meglumine antimoniate (MA) are the primary treatments for leishmaniasis, a complex disease caused by protozoan parasites of the genus Leishmania . Despite over 70 years of clinical use, their mechanisms of action, toxicity and pharmacokinetics have not been fully elucidated.
Borborema, Samanta Etel Treiger +3 more
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Ocorrência de anticorpos anti-Neospora caninum e anti-Toxoplasma gondii em cães com leishmaniose visceral [PDF]
, 2011 Uninfected dogs and those naturally infected with Leishmania chagasi exhibiting different clinical forms of disease were evaluated for the presence of anti-Neospora caninum and anti-Toxoplasma gondii antibodies.
Frézard, Frédéric +7 more
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Theranostic applications of phage display to control leishmaniasis: Selection of biomarkers for serodiagnostics, vaccination, and immunotherapy [PDF]
, 2017 © 2015, Sociedade Brasileira de Medicina Tropical. All rights reserved. Phage display is a high-throughput subtractive proteomic technology used for the generation and screening of large peptide and antibody libraries.
Chávez-Fumagalli, Miguel A. +5 more
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Tissue Cytokine Responses in Canine Visceral Leishmaniasis [PDF]
, 2001 To elucidate the local tissue cytokine response of dogs infected with Leishmania chagasi, cytokine mRNA levels were measured in bone marrow aspirates from 27 naturally infected dogs from Brazil and were compared with those from 5 uninfected control ...
Courtenay, O. +6 more
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The contribution of immune evasive mechanisms to parasite persistence in Visceral Leishmaniasis
Frontiers in Immunology, 2016 Leishmania is a genus of protozoan parasites that give rise to a range of diseases called Leishmaniasis that affects annually an estimated 1.3 million people from 88 countries.
Elisangela Oliveira De Freitas +4 more
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A Century of Epidemiological Advances in Cutaneous and Visceral Leishmaniasis in Algeria. [PDF]
J Parasitol ResLeishmaniasis is a group of diseases transmitted by sandflies, affecting humans and animals, with three clinical presentations: cutaneous, mucosal, and visceral. The disease is caused by the parasite Leishmania and is a significant global health issue, with approximately two million cases annually and 350 million people at risk.
Eddaikra N, Benikhlef R, Sereno D.
europepmc +2 more sources
Impact of leishmaniasis on public health
Journal of Venomous Animals and Toxins including Tropical Diseases, 2006 Leishmaniasis is a parasitic zoonosis caused by protozoans of the genus Leishmania transmitted by insects known as phlebotomines, which are found in wild or urban environments.
L. B Camargo, H. Langoni
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Early suppression of lymphoproliferative response in dogs with natural infection by Leishmania infantum. [PDF]
, 1999 Dogs are the domestic reservoirs of zoonotic visceral leishmaniasis caused by Leishmania infantum. Early detection of canine infections evolving to clinically patent disease may be important to leishmaniasis control.
CIARAMELLA, PAOLO +8 more
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