Structures, targets and recent approaches in anti-leishmanial drug discovery and development. [PDF]
Recent years have seen a significant improvement in available treatment options for leishmaniasis. Two new drugs, miltefosine and paromomycin, have been registered for the treatment of visceral leishmaniasis (VL) in India since 2002.
Seifert, Karin
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CR1, the C3b receptor, mediates binding of infective Leishmania major metacyclic promastigotes to human macrophages. [PDF]
R P Da Silva+3 more
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INTRODUCTION Leishmania major is the causative agent of zoonotic cutaneous leishmaniasis (ZCL), and great gerbils are the main reservoir hosts in Iran. Abarkouh in central Iran is an emerging focal point for which the reservoir hosts of ZCL are unclear ...
N. Najafzadeh+7 more
semanticscholar +1 more source
In this review, we summarize the current knowledge concerning the eukaryotic protozoan parasite Leishmania tarentolae, with a main focus on its potential for biotechnological applications.
Klatt, S.+3 more
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Structure and expression of the hsp 70 gene family ofLeishmania major [PDF]
Mary Gwo-Shu Lee+3 more
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Hybridization in parasites: consequences for adaptive evolution, pathogenesis and public health in a changing world [PDF]
[No abstract ...
A Berry+108 more
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In vitro activity of sulfonamides and sulfones against Leishmania major promastigotes [PDF]
Maristela Peckle Peixoto+1 more
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BackgroundTwo Leishmania major ribosomal proteins L3 (LmL3) and L5 (LmL5) have been described as protective molecules against cutaneous leishmaniasis due to infection with L.
Laura Ramírez+12 more
semanticscholar +1 more source
Prophylactic immunization against experimental leishmaniasis. V. Mechanism of the anti-protective blocking effect induced by subcutaneous immunization against Leishmania major infection. [PDF]
F Y Liew+3 more
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A family of heat shock protein 70-retated genes are expressed in the promastigotes ofLeishmania major [PDF]
Susan Searle+4 more
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