Results 81 to 90 of about 9,977 (186)

Leishmania major infection in a dog with cutaneous manifestations [PDF]

Parasites & Vectors, 2016
Leishmania major is a main cause of cutaneous leishmaniasis in humans in an area that stretches from India through Central Asia, the Middle East, to North and West Africa. In Israel, it is a common infection of humans with rodents as the reservoir hosts and Phlebotomus papatasi as its sand fly vector.A 6 months old spayed female mixed breed dog was ...
Baneth, Gad, Nachum-Biala, Yaarit, Shabat Simon, Maytal, Brenner, Ori, Gaier, Sarit, Rojas, Alicia, Yasur-Landau, Daniel   +6 more
openaire   +2 more sources

Pancytopenia With Hypocellular Bone Marrow Revealing Extrahepatic Portal Venous Obstruction and Cavernous Transformation in a Child: A Case Report of a Diagnostic Challenge

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Extrahepatic portal venous obstruction (EHPVO) is a leading cause of prehepatic portal hypertension in children, particularly in developing countries. While upper gastrointestinal bleeding is the most common presentation, EHPVO may rarely manifest predominantly with hematological abnormalities due to hypersplenism, posing a diagnostic ...
Swekchha Adhikari, Aakash Pandit, Melisha Koirala, Biplav Lamichhane, Ram Khadka, Aashish Panta, Shuvra Rimal   +6 more
wiley   +1 more source

Oligopeptidase B deficient mutants of Leishmania major [PDF]

Molecular and Biochemical Parasitology, 2011
Oligopeptidase B is a clan SC, family S9 serine peptidase found in gram positive bacteria, plants and trypanosomatids. Evidence suggests it is a virulence factor and thus therapeutic target in both Trypanosoma cruzi and T. brucei, but little is known about its function in Leishmania. In this study L.
Munday, Jane C., McLuskey, Karen, Brown, Elaine, Coombs, Graham H, Mottram, Jeremy C   +4 more
openaire   +4 more sources

Beyond birds: rethinking bird‐centered pathogen models in light of insect migration

Ecography, Volume 2026, Issue 6, June 2026.
Migration redistributes biomass, nutrients, and pathogens across ecosystems. For decades, migratory birds have been treated as the default long‐distance pathogen vectors, shaping both conceptual frameworks and empirical models of disease ecology.
Virginia Morandini
wiley   +1 more source

Proteophosophoglycans regurgitated by Leishmania-infected sand flies target the L-arginine metabolism of host macrophages to promote parasite survival [PDF]

, 2009
All natural Leishmania infections start in the skin; however, little is known of the contribution made by the sand fly vector to the earliest events in mammalian infection, especially in inflamed skin that can rapidly kill invading parasites.
Podinovskaia, M, Rogers Matthew, Matthew Rogers, Rogers, Matthew E., Choi Beak-San, Choi, BS, Maria Podinovskaia, Kropf Pascale, Rogers, M, Bates, P, Dillon, R, Ingrid Müller, Kropf, P, Müller, Ingrid, Choi, B. S., Bates Paul, Podinovskaia, M., Kropf, P., Kropf, Pascale, Podinovskaia, Maria, Beak-San Choi, Rogers, Matthew, Dillon, Rod, Rod Dillon, Muller, I, Pascale Kropf, Dillon Rod, Bates, Paul, Müller Ingrid, Podinovskaia Maria, Choi, Beak-San, Paul Bates, Müller, I.   +32 more
core   +1 more source

The immunology of susceptibility and resistance to Leishmania major in mice [PDF]

Nature Reviews Immunology, 2002
Established models of T-helper-2-cell dominance in BALB/c mice infected with Leishmania major -- involving the early production of interleukin-4 by a small subset of Leishmania-specific CD4+ T cells -- have been refined by accumulating evidence that this response is not sufficient and, under some circumstances, not required to promote susceptibility ...
David, Sacks, Nancy, Noben-Trauth
openaire   +2 more sources

Glycoprotein 63 (gp63) genes show gene conversion and reveal the evolution of Old World Leishmania.

, 2006
Species of the subgenus Leishmania (Leishmania) cause the debilitating disease leishmaniasis on four continents. Species grouped within the Leishmania donovani complex cause visceral leishmaniasis, a life-threatening disease, often associated with ...
Mauricio, Isabel L, Figuerola, Jordi, Soriguer, Ramón C., Miles, Michael A, López, Guillermo, Stothard, J Russell, Gaunt, Michael W   +6 more
core   +1 more source

Leishmania manipulation of sand fly feeding behavior results in enhanced transmission [PDF]

, 2007
In nature the prevalence of Leishmania infection in whole sand fly populations can be very low (
Rogers, Matthew E, Rogers Matthew E, Bates, Paul, Matthew E. Rogers, Matthew E Rogers, Bates, Paul A, Paul A Bates, Rogers, Matthew E., Bates Paul A, Paul A. Bates   +9 more
core   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

MedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang, Jingfei Shi, Linlin Xu, Guangrui Zhao, Yue Chen, Lin Cheng, Xiaokang Li, Zhigang Sun, Shuhong Huang   +8 more
wiley   +1 more source

Genetic diversity in the Leishmania donovani complex. [PDF]

The Leishmania donovani complex comprises four described species: L. donovani, L. archibaldi, L. infantum and L. chagasi. L. chagasi is the only New World species and has been considered similar to L.
Mauricio, Isabel Larguinho
core   +1 more source