Results 81 to 90 of about 4,849,377 (223)
The immunology of susceptibility and resistance to Leishmania major in mice [PDF]
Nature Reviews Immunology, 2002 Established models of T-helper-2-cell dominance in BALB/c mice infected with Leishmania major -- involving the early production of interleukin-4 by a small subset of Leishmania-specific CD4+ T cells -- have been refined by accumulating evidence that this response is not sufficient and, under some circumstances, not required to promote susceptibility ...
David, Sacks, Nancy, Noben-Trauth
openaire +2 more sources
Tropical Medicine &International Health, EarlyView.ABSTRACT Background Cutaneous leishmaniasis (CL) is a major public health challenge in Ethiopia, with 20–30,000 new cases annually. Limited awareness and misconceptions contribute to delayed care seeking, stigma, prolonged healing, and reduced uptake of preventive measures in CL‐endemic communities.
Takele Gezahegn Demie +13 more
wiley +1 more source
Metabolic variation during development in culture of Leishmania donovani promastigotes [PDF]
, 2011 The genome sequencing of several Leishmania species has provided immense amounts of data and allowed the prediction of the metabolic pathways potentially operating.
Cordeiro-da-Silva, Anabela +2 more
core +4 more sources
Veterinary Clinical Pathology, EarlyView.ABSTRACT Background Hemophagocytic syndrome (HPS)/hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening hyperinflammatory syndrome characterized by immune dysregulation, cytokine overproduction, hemophagocytosis, cytopenias, and multiorgan dysfunction.
Joanne B. Messick
wiley +1 more source
Zoonoses and Public Health, EarlyView.ABSTRACT Introduction Cryptosporidium is responsible not only for large economic losses in the livestock sector, but also for high mortality in infants and immunocompromised people all over the world. Although multiple treatments have been tested in both animals and humans, no drug has yet been found to be 100% effective.
María Cristina Del Río +6 more
wiley +1 more source
Immunity to Leishmania mexicana parasite [PDF]
, 2014 Background: Cutaneous Leishmaniasis caused by the Leishmania mexicana complex is associated with unpleasant or disfiguring lesions, for which there only limited treatment options. The life cycle of L.
Ali, KSM
core
Glycoprotein 63 (gp63) genes show gene conversion and reveal the evolution of Old World Leishmania.
, 2006 Species of the subgenus Leishmania (Leishmania) cause the debilitating disease leishmaniasis on four continents. Species grouped within the Leishmania donovani complex cause visceral leishmaniasis, a life-threatening disease, often associated with ...
Mauricio, Isabel L +6 more
core +1 more source
From genomes to vaccines: Leishmania as a model:Leishmania as a model [PDF]
, 2002 The 35 Mb genome of Leishmania should be sequenced by late 2002. It contains approximately 8500 genes that will probably translate into more than 10 000 proteins.
Vilo, Jaak +11 more
core +1 more source
Expression of Human CYP2D6 in Artificial Cells Based on Polymer‐Lipid Hybrid Vesicles
ChemBioChem, Volume 27, Issue 21, 12 November 2026.Expression of eGFP and human cytochrome P450 2D6 (CYP2D6) within the lumen of giant polymer‐lipid hybrid vesicles using a Leishmania tarentolae‐based cell‐free protein expression system is illustrated. Both proteins were expressed in the vesicle lumen, and low‐polymer‐content hybrid vesicles were the most suitable scaffolds for CYP2D6 expression with ...
Sarah Dahl +7 more
wiley +1 more source
Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.Abstract A 5‐year‐old, spayed, female Shiba Inu was presented with a 6‐week history of reduced appetite, lethargy and generalised stiffness, which showed only limited improvement despite anti‐inflammatory treatment. The most significant clinical abnormalities were pyrexia, stiffness, pain on joint manipulation and cutaneous lesions. Laboratory findings
Jeanne Bergeat +6 more
wiley +1 more source