Results 81 to 90 of about 71,650 (224)

Efficacy of Thermotherapy to Treat Cutaneous Leishmaniasis Caused by Leishmania tropica in Kabul, Afghanistan: A Randomized, Controlled Trial [PDF]

, 2005
BACKGROUND: Pentavalent antimony is the agent recommended for treatment of cutaneous leishmaniasis (CL). Its use is problematic, because it is expensive and because of the potential for drug-associated adverse effects during a lengthy and painful ...
Aram H, Arana BA, Babajev KB, Berman JD, Berman JD, C. R. Davies, J. Kolaczinski, J. R. David, Junaid AJN, M. Bismullah, M. Mohsen, M. Wahid, Navin TR, Neva FA, Noyes H, R. J. Quinnell, R. Reithinger, Reithinger R, Rodriguez ME, Sacks DL, Sharquie KE, Tallab TM, Velasco-Castrejon O, World Health Organization   +23 more
core   +1 more source

Recombinant LPG3 Protein From Leishmania chagasi as an Antigen for the Diagnosis of Canine Visceral Leishmaniasis

Tropical Medicine &International Health, EarlyView.
ABSTRACT Visceral leishmaniasis (VL) is a human neglected tropical disease in which dogs participate as reservoirs of the etiological agent Leishmania chagasi. The identification of infected dogs is important to the control of VL, and recombinant proteins are strong antigen candidates for canine visceral leishmaniasis (CVL) serodiagnosis. In this work,
Thaís Viana Fialho Martins, Anna Cláudia Alves de Souza, Bianca Meireles Miranda, Ronny Francisco de Souza, Daniel Silva Sena Bastos, Neverton José Silva Ferreira, Tiago Antônio de Oliveira Mendes, Celeste da Silva Freitas de Souza, George Luiz Lins Machado‐Coelho, Maria Terezinha Bahia, Leandro Licursi de Oliveira, Juliana Lopes Rangel Fietto, Eduardo de Almeida Marques‐da‐Silva   +12 more
wiley   +1 more source

Comparison of Protein Profile of Killed and Autoclaved Leishmania Major Using Polyacrylamide Gel Electrophoresis

مجله دانشکده پزشکی اصفهان, 2013
Background: Leishmania is a genus of trypanosomatid protozoa which causes a wide spectrum of diseases ranging from a self-healing cutaneous lesion to a vital visceral form of the disease.
Reza Arjmand, Simindokht Soleimanifard, Sedigheh Saberi, Sepideh Tolouei, Ali Khamesipour, Seyed Hossein Hejazi   +5 more
doaj  

Paf-Metabolic Enzymes and Paf-like Activity in and Promastigotes

European Journal of Inflammation, 2011
Leishmania spp are obligate intracellular protozoan parasites of the mononuclear phagocyte system that cause a spectrum of diseases known as leishmaniasis.
P. Chatzovoulos, A.B. Tsoupras, M. Samiotaki, G. Panayotou, C.A. Demopoulos, E. Dotsika   +5 more
doaj   +1 more source

Hybridization in parasites: consequences for adaptive evolution, pathogenesis and public health in a changing world [PDF]

, 2015
[No abstract ...
A Berry, A Koukounari, AJ Norton, AR Laird, B Schelkle, BL Webster, BL Webster, BL Webster, BR Grant, C Astrom, C Gyles, CA Machado, CD Criscione, CM Brasier, CM Lively, CM Lively, CS Clarkson, CS Wondji, D Menge, D Rollinson, D Weetman, DB Dunams-Morel, DE Neafsey, Deborah F. Smith, DR Brooks, DR Dittrich-Reed, E Inbar, E Mancini, E Redman, E Strauch, EH Stukenbrock, EJ Baack, GL Nichols, Glenn F Rall, H Krehenwinkel, H Ochman, H Ochman, HD Mawejje, HJ Müller, HV Pates, I Goodhead, J Boissier, J Davies, J Hawks, J Mallet, J Mavarez, JA Coyne, JA Patz, JC Semenza, JM Kelly, Joanne P. Webster, JP Webster, JP Webster, JT Detwiler, Kayla C. King, KD Lafferty, LA Messenger, LA Messenger, LAT Tchuente, LC Norris, LH Rieseberg, LH Rieseberg, M Arnold, M Lynch, M Schumer, M Worobey, MA Miles, MA Nowak, MB Rogers, MB Rogers, MC Fontaine, ME Grigg, MF Dybdahl, MG Taylor, Michael A. Brockhurst, MJ Gibbs, ML Arnold, ML Arnold, ML Steinauer, MW Gaunt, NH Barton, NR Sturm, NS Akopyants, O Seehausen, P Martens, P Volf, P Volf, PW Hedrick, R Abbott, RA Farrer, RB Stelkens, RB Stelkens, RDH Barrett, Rike B. Stelkens, RS Ramiro, S Edmands, S Hales, S Manguin, S Moore, T Dobzhansky, T Huyse, T Huyse, TH Le, U Chaudhry, W Alves, W Choochote, W Li, Y Lee, Y Song   +108 more
core   +2 more sources

Evaluation of the Cutaneous Immunological Milieu Before and After Treatment With Meglumine Antimoniate in Dogs Naturally Affected by Leishmaniosis due to Leishmania infantum

Veterinary Dermatology, EarlyView.
Background: Canine leishmaniosis (CanL) is a zoonotic disease of variable severity. The typical immune response is driven by an exaggerated humoral immune response. Protective immunity is mediated by pro‐inflammatory cytokines that enhance macrophage leishmanicidal activity. Objective: To evaluate the cutaneous and the systemic immune responses as well
M. Platenik, A. Di Loria, L. Archer, M. Saridomichelakis, A. S. Benvenuto, D. Santoro   +5 more
wiley   +1 more source

Canine Leishmaniasis in Rio de Janeiro, Brazil (2000–2015): Taxonomic Characterisation of Etiological Agents and Geospatial Case Analysis

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Canine Leishmaniasis is a vector‐borne zoonotic disease caused by several species of protozoa of the genus Leishmania. In the state of Rio de Janeiro (RJ), Leishmania braziliensis is the most prevalent species causing tegumentary leishmaniasis (TL) and Leishmania infantum is the main causative agent of visceral leishmaniasis (VL).
Luciana de Freitas Campos Miranda, Laryssa Fabiano do Rosário Coelho, Samanta Cristina das Chagas Xavier, Artur Augusto Velho Mendes Junior, Renan Nunes Albuquerque, Aline Fagundes da Silva, Andreza Pain Marcelino, Fernanda Nunes Santos, Sandro Antonio Pereira, Rodrigo Caldas Menezes, Armando de Oliveira Schubach   +10 more
wiley   +1 more source

Super Infection of Cutaneous Leishmaniasis Caused by Leishmania major and L. tropica to Crithidia fasciculata in Shiraz, Iran

Iranian Journal of Public Health, 2019
Background: The aims of the current study were to determined present status of CL in Shiraz City, identify the causative species of Leishmania and conduct phylogenetic evaluations in detected parasites Methods: This study was conducted on 70 ...
Aliyar MIRZAPOUR, Alireza BADIRZADEH, Marzieh ASHRAFMANSOURI, Hamed BEHNIAFAR, Maryam NOROUZI, Hakim AZIZI, Mahmoodreza BEHRAVAN, Seyyed Javad SEYYED TABAEI   +7 more
doaj   +1 more source

Exploring 6‐Hydroxy‐3‐Aryl/Heteroarylcoumarins as Promising Candidates Against Trypanosoma cruzi

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
New therapies are urgently needed for Chagas disease, and screening of 6‐hydroxy‐3‐aryl/heteroarylcoumarin derivatives identified highly selective compounds with potent activity against T. cruzi. In particular, derivative 1f showed submicromolar trypomastigote potency, dual‐stage activity, and inhibition of amastigote‐to‐trypomastigote differentiation,
C. N. Pereira, L. da Silva Lara, S. da Costa Lanera, T. Pérez de Souza, M. C. de Souza Pereira, G. L. Delogu, M. Silva dos Santos, M. J. Matos   +7 more
wiley   +1 more source

An Unusual Presentation of Cutaneous Leishmaniasis in a Patient with Substance Use: A Diagnostic and Management Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT In patients with atypical ulcers and travel history to endemic areas, a comprehensive diagnostic workup for cutaneous leishmaniasis is imperative. This case confirms Leishmania tropica through combined microscopy, culture, and PCR, leading to successful treatment with systemic glucantime and adjunctive wound care.
Hossein Pazoki, Eissa Soleymani, Shirafkan Kordi, Mahdi Fakhar   +3 more
wiley   +1 more source