Results 91 to 100 of about 71,650 (224)

Heterogeneity of cysteine proteinases in Leishmania braziliensis and Leishmania major.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1994
Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) with acrylamide copolymerized with gelatin (substrate-SDS-PAGE) was used to compare promastigote proteinases from two Leishmania species (L. braziliensis and L. major-like). Substrate-SDS-PAGE resolved at least 6 distinct proteinase activities with relative molecular masses between 20
C R, Alves, M C, Marzochi, S, Giovanni-de-Simone   +2 more
openaire   +2 more sources

A Killing Disease Epidemic Among Displaced Sudanese Population Identified as Visceral Leishmaniasis. [PDF]

, 1991
A fatal disease epidemic affected the Bentiu area in southern Sudan and led to a mass migration of the Nuer tribe searching for treatment. The initially available information revealed a high mortality rate due to a possible occurrence of tuberculosis ...
Chantal, B, de Beer, P, Deng, L, el Harith, A, Semiao-Santos, S J, van Grootheest, M   +5 more
core   +2 more sources

Structural basis of secreted acid phosphatase polymerization in the Leishmania parasite

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Enzymes that assemble into filaments typically transition between protomeric and polymeric states in response to cellular conditions. In contrast, the secreted acid phosphatase (SAP) of Leishmania, one of the most abundant extracellular glycoproteins produced by the parasite and regarded as a major virulence factor in the neglected tropical ...
Priyanka Bose, Irit Dahan, Alexander Upcher, Ran Zalk, Iris Grossman‐Haham   +4 more
wiley   +1 more source

A new landscape of host–protozoa interactions involving the extracellular vesicles world [PDF]

, 2018
This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. © Cambridge University Press 2018Extracellular vesicles (EVs) are released by a wide number of cells including ...
Bruno Gavinho, Combes, Dlugonska, Hart, Ingrid Evans-Osses, Izadora Volpato Rossi, Jameel Inal, Kho, Lechartier, Marcel I. Ramirez, Nten, Zingales   +11 more
core   +2 more sources

In Vitro Evaluation of Antileishmanial Activity of Commiphora myrrha Essential Oil Nanoliposome

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study investigates the efficacy of nanoliposomal formulations containing myrrh essential oil in combating Leishmania protozoa in laboratory settings. Myrrh essential oil and nanoliposomes were prepared in RPMI‐1640 medium at concentrations of 1, 2, 5 and 10 µg/dL.
Zahra Akbari, Mohammad Reza Youssefi, Mohaddeseh Abouhosseini Tabari   +2 more
wiley   +1 more source

Mixed Signals: T Cells as Architects of IgE Immunity

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Food allergen‐specific IgE can cause significant pathology, yet the pathways that generate pathogenic, high‐affinity IgE remain incompletely understood. Increasing evidence suggests that IgE responses arise from the integration of multiple, and sometimes opposing, T cell–derived cues.
Abigail L. Tierney, Wallace P. Bezerra, Stephanie C. Eisenbarth, Adam Williams   +3 more
wiley   +1 more source

Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice [PDF]

, 2009
The small GTPase Rab5 is a key regulator of endosome/phagosome maturation and in intravesicular infections marks a phagosome stage at which decisions over pathogen replication or destruction are integrated.
Aebischer, Toni, Blackburn, Clare, Brand, Janko, Brinkmann, Volker, Hoffmann, Kirstin, Lippuner, Christoph, Paape, Daniel, Paterou, Athina, Richardson, Melville, Smith, Andrew   +9 more
core   +1 more source

Metalloids: Semi as Metals yet Full of Antimicrobial Potential

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Kevin Böhm, Muhammad Jawad Nasim, Claus Jacob   +2 more
wiley   +1 more source

Targeting Kinetoplastid Parasites with ProTide Prodrugs: A Proof‐of‐Concept Study

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Neglected tropical diseases (NTDs) remain a major global health challenge, particularly in low‐ and middle‐income countries. Kinetoplastid parasites causing Chagas disease, leishmaniasis, and African trypanosomiasis rely on host purine salvage pathways, making nucleoside analogues attractive therapeutic candidates.
Silvester Lowe, Vishal Satikuvar, Tanjia M. Syeda, Monica Cal, Pascal Mäser, Marcel Kaiser, Hachemi Kadri   +6 more
wiley   +1 more source

Leishmania spp Infection in Patients and Great Gerbils (Rhombomys opimus) in a High-Risk Focus of Zoonotic Cutaneous Leishmaniasis in Central Iran: a Microscopic and Molecular Survey

Journal of Arthropod-Borne Diseases
Background: Zoonotic cutaneous leishmaniasis (ZCL) is an endemic disease in Varzaneh City where Leishmania ma­jor is the causative agent and the great gerbil, Rhombomys opimus, is the main reservoir host of the disease.
Narges Marvi Moghadam, Mehdi Mohebali, Yavar Rassi, Ali Reza Zahraei-Ramazani, Mohammad Ali Oshaghi, Reza Jafari, Mahboubeh Fatemi, Mohammad Hossein Arandian, Hamid Abdoli, Nilufar Shareghi, Maryam Ghanei, Nilufar Jalali-Zand, Arshad Veysi, Javad Ramazanpoor, Kurosh Aminian, Ali Salehi, Ali Khamesipour, Amir Ahmad Akhavan   +17 more
doaj   +1 more source