Results 91 to 100 of about 4,849,377 (223)
Anaplastic cutaneous plasmacytoma in a dog
Abstract Extramedullary cutaneous plasmacytoma is an uncommon tumour in dogs and rare in cats, often linked to chronic inflammation or prolonged antigenic stimulation. It typically affects middle‐aged to older dogs, involving the head, trunk, limbs and digits.
André Castilhano Marcelino Silva +4 more
wiley +1 more source
Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background [PDF]
The evolution of drug-resistance in pathogens is a major global health threat. Elucidating the molecular basis of pathogen drug-resistance has been the focus of many studies but rarely is it known whether a drug-resistance mechanism identified is ...
Dujardin, Jean-Claude +8 more
core +4 more sources
Background: Zoonotic cutaneous leishmaniasis (ZCL) is an endemic disease in Varzaneh City where Leishmania major is the causative agent and the great gerbil, Rhombomys opimus, is the main reservoir host of the disease.
Narges Marvi Moghadam +17 more
doaj +1 more source
Aspects épidemiocliniques et évolutifs chez 157 cas de leishmaniose cutanée au Maroc
Connue au Maroc depuis la fin du XIX siècle, la leishmaniose cutanée (LC) constitue un problème de santé publique dans notre pays. Le but de notre travail est de décrire le profil épidémioclinique et l'évolution post thérapeutique chez les patients ayant
Naoufal Hjira +6 more
doaj +1 more source
ABSTRACT Introduction Toscana virus (TOSV) and Leishmania species are sand fly‐borne pathogens that pose a significant public health threat and an increasing risk of exposure in Europe. The objective of this study was to identify the phleboviruses circulating in an area endemic for sand fly‐borne pathogens and to estimate infection prevalence in wild ...
Andrés Torres‐Llamas +8 more
wiley +1 more source
Background: Cutaneous leishmaniasis (CL) remains a serious public health concern in Kerman Province, eastern Iran. This study was aimed to conduct a comprehensive review and highlights various aspects of CL in the province of Kerman.
Iraj Sharifi +11 more
doaj
Hit‐to‐lead optimization of morpholinephenylbenzamides reveals key structure–activity relationships against Trypanosoma cruzi and Leishmania infantum. Potency, selectivity, and ADME properties are differentially improved across the series, identifying compounds 20, 24, and 16 as complementary templates for the future design of dual antiparasitic leads.
Danilo Nascimento Farago +15 more
wiley +1 more source
Functional analysis of leishmania cyclopropane fatty acid synthetase [PDF]
The single gene encoding cyclopropane fatty acid synthetase (CFAS) is present in Leishmania infantum, L. mexicana and L. braziliensis but absent from L. major, a causative agent of cutaneous leishmaniasis. In L.
Mottram Jeremy C. +40 more
core +1 more source
Characterization of NUDIX Hydrolase from Leishmania major
Abstract Hydrolysis of a wide range of organic pyrophosphates is carried out by a family of NUDIX hydrolases present ubiquitously in all kingdoms of life. NUDIX hydrolases have a highly conserved 23 amino acid long NUDIX box domain. When the genome sequence of Leishmania major, was analyzed for NUDIX motif, it revealed nine proteins had NUDIX ...
Mahendra D, Jamdhade +5 more
openaire +2 more sources
Epidemiological Study of Cutaneous Leishmaniasis and Identification of Etiological Species
Background and purpose: Cutaneous leishmaniasis is endemic parasitic disease in different regions of the world especially in Iran. Khorasan province is endemic for anthroponootic and zoonotic cutaneous leishmaniasis with unequal outbreak.
Abdolmajid Fata +5 more
doaj

