Results 91 to 100 of about 4,849,377 (223)

Anaplastic cutaneous plasmacytoma in a dog

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract Extramedullary cutaneous plasmacytoma is an uncommon tumour in dogs and rare in cats, often linked to chronic inflammation or prolonged antigenic stimulation. It typically affects middle‐aged to older dogs, involving the head, trunk, limbs and digits.
André Castilhano Marcelino Silva   +4 more
wiley   +1 more source

Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background [PDF]

open access: yes, 2012
The evolution of drug-resistance in pathogens is a major global health threat. Elucidating the molecular basis of pathogen drug-resistance has been the focus of many studies but rarely is it known whether a drug-resistance mechanism identified is ...
Dujardin, Jean-Claude   +8 more
core   +4 more sources

Leishmania spp Infection in Patients and Great Gerbils (Rhombomys opimus) in a High-Risk Focus of Zoonotic Cutaneous Leishmaniasis in Central Iran: a Microscopic and Molecular Survey

open access: yesJournal of Arthropod-Borne Diseases
Background: Zoonotic cutaneous leishmaniasis (ZCL) is an endemic disease in Varzaneh City where Leishmania ma­jor is the causative agent and the great gerbil, Rhombomys opimus, is the main reservoir host of the disease.
Narges Marvi Moghadam   +17 more
doaj   +1 more source

Aspects épidemiocliniques et évolutifs chez 157 cas de leishmaniose cutanée au Maroc

open access: yesThe Pan African Medical Journal, 2014
Connue au Maroc depuis la fin du XIX siècle, la leishmaniose cutanée (LC) constitue un problème de santé publique dans notre pays. Le but de notre travail est de décrire le profil épidémioclinique et l'évolution post thérapeutique chez les patients ayant
Naoufal Hjira   +6 more
doaj   +1 more source

Natural Infection by Toscana Virus and Other Phleboviruses in Wild Sand Flies From Spain: Prevalence, Genetic Characterization and Tripartite Interactions With Leishmania infantum and Wolbachia

open access: yesZoonoses and Public Health, Volume 73, Issue 7, Page 655-669, November 2026.
ABSTRACT Introduction Toscana virus (TOSV) and Leishmania species are sand fly‐borne pathogens that pose a significant public health threat and an increasing risk of exposure in Europe. The objective of this study was to identify the phleboviruses circulating in an area endemic for sand fly‐borne pathogens and to estimate infection prevalence in wild ...
Andrés Torres‐Llamas   +8 more
wiley   +1 more source

A Comprehensive Review of Cutaneous Leishmaniasis in Kerman Province, Southeastern Iran- Narrative Review Article

open access: yesIranian Journal of Public Health, 2015
Background: Cutaneous leishmaniasis (CL) remains a serious public health concern in Kerman Province, eastern Iran. This study was aimed to conduct a comprehensive review and highlights various aspects of CL in the province of Kerman.
Iraj Sharifi   +11 more
doaj  

Synthesis, Antiparasitic Activity, and ADME Profile of Morpholinephenylbenzamides: A Pharmacological Study Against Chagas Disease and Visceral Leishmaniasis

open access: yesChemMedChem, Volume 21, Issue 19, 14 October 2026.
Hit‐to‐lead optimization of morpholinephenylbenzamides reveals key structure–activity relationships against Trypanosoma cruzi and Leishmania infantum. Potency, selectivity, and ADME properties are differentially improved across the series, identifying compounds 20, 24, and 16 as complementary templates for the future design of dual antiparasitic leads.
Danilo Nascimento Farago   +15 more
wiley   +1 more source

Functional analysis of leishmania cyclopropane fatty acid synthetase [PDF]

open access: yes, 2012
The single gene encoding cyclopropane fatty acid synthetase (CFAS) is present in Leishmania infantum, L. mexicana and L. braziliensis but absent from L. major, a causative agent of cutaneous leishmaniasis. In L.
Mottram Jeremy C.   +40 more
core   +1 more source

Characterization of NUDIX Hydrolase from Leishmania major

open access: yesActa Parasitologica
Abstract Hydrolysis of a wide range of organic pyrophosphates is carried out by a family of NUDIX hydrolases present ubiquitously in all kingdoms of life. NUDIX hydrolases have a highly conserved 23 amino acid long NUDIX box domain. When the genome sequence of Leishmania major, was analyzed for NUDIX motif, it revealed nine proteins had NUDIX ...
Mahendra D, Jamdhade   +5 more
openaire   +2 more sources

Epidemiological Study of Cutaneous Leishmaniasis and Identification of Etiological Species

open access: yesJournal of Mazandaran University of Medical Sciences, 2018
Background and purpose: Cutaneous leishmaniasis is endemic parasitic disease in different regions of the world especially in Iran. Khorasan province is endemic for anthroponootic and zoonotic cutaneous leishmaniasis with unequal outbreak.
Abdolmajid Fata   +5 more
doaj  

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