Results 71 to 80 of about 9,977 (186)
Metabolic variation during development in culture of Leishmania donovani promastigotes
The genome sequencing of several Leishmania species has provided immense amounts of data and allowed the prediction of the metabolic pathways potentially operating.
Cordeiro-da-Silva, Anabela +8 more
core +1 more source
Visualisation of Leishmania donovani fluorescent hybrids during early stage development in the sand fly vector. [PDF]
BACKGROUND: The Leishmania protozoan parasites cause devastating human diseases. Leishmania have been considered to replicate clonally, without genetic exchange.
Petr Volf +29 more
core +1 more source
Background: Leishmania is a genus of trypanosomatid protozoa which causes a wide spectrum of diseases ranging from a self-healing cutaneous lesion to a vital visceral form of the disease.
Reza Arjmand +5 more
doaj
Paf-Metabolic Enzymes and Paf-like Activity in and Promastigotes
Leishmania spp are obligate intracellular protozoan parasites of the mononuclear phagocyte system that cause a spectrum of diseases known as leishmaniasis.
P. Chatzovoulos +5 more
doaj +1 more source
ABSTRACT Visceral leishmaniasis (VL) is a human neglected tropical disease in which dogs participate as reservoirs of the etiological agent Leishmania chagasi. The identification of infected dogs is important to the control of VL, and recombinant proteins are strong antigen candidates for canine visceral leishmaniasis (CVL) serodiagnosis. In this work,
Thaís Viana Fialho Martins +12 more
wiley +1 more source
The cutaneous leishmaniasis is caused by the protozoan of the genus Leishmania. It is considered by WHO as a public health issue and a neglected disease, which affects rural workers and it is also a risk to travelers in endemic areas. The conventional treatment is toxic and leads to severe side effects.
Juliana Guerra, Pinto +5 more
openaire +2 more sources
1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman +7 more
wiley +1 more source
Endosomes, Glycosomes, and Glycosylphosphatidylinositol Catabolism in Leishmania major [PDF]
Glycosylphosphatidylinositols (GPIs) serve as membrane anchors of polysaccharides and proteins in the protozoan parasite Leishmania major. Free GPIs that are not attached to macromolecules are present in L. major as intermediates of protein-GPI and polysaccharide-GPI synthesis or as terminal glycolipids.
Zhifeng, Zheng +3 more
openaire +2 more sources
Background: The aims of the current study were to determined present status of CL in Shiraz City, identify the causative species of Leishmania and conduct phylogenetic evaluations in detected parasites Methods: This study was conducted on 70 ...
Aliyar MIRZAPOUR +7 more
doaj +1 more source
Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros +5 more
wiley +1 more source

