Results 51 to 60 of about 4,660,147 (222)

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

The role of leishmania proteophosphoglycans in sand fly transmission and infection of the Mammalian host. [PDF]

, 2012
Leishmania are transmitted by the bite of their sand fly vector and this has a significant influence on the virulence of the resulting infection. From our studies into the interaction between parasite, vector, and host we have uncovered an important ...
Rogers, Matthew E, Matthew Edward Rogers, Matthew E. Rogers   +2 more
core   +1 more source

Development and Characterization of Liposomes Containing a Zn(II) Porphyrin Derivative for the Application of Photodynamic Therapy in the Treatment of Breast Cancer

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives This study aims to synthesize and characterize lipid nanosystems (liposomes) for the incorporation of a Zn(II) porphyrin derivative, Zn(II) meso‐tetrakis(N‐n‐hexylpyridinium‐2‐yl)porphyrin (ZnTnHex‐2‐PyP4+, ZnPH), intending to employ an alternative method of treatment, such as photodynamic therapy (PDT), for breast cancer (BC ...
Kammila Martins Nicolau Costa, José Ferreira Sarmento‐Neto, Júlio Santos Rebouças, Ricardo Olímpio de Moura, John F. Callan, João Augusto Oshiro‐Junior   +5 more
wiley   +1 more source

LeishCyc: a biochemical pathways database for Leishmania major [PDF]

BMC Systems Biology, 2009
Abstract Background Leishmania spp. are sandfly transmitted protozoan parasites that cause a spectrum of diseases in more than 12 million people worldwide. Much research is now focusing on how these parasites adapt to the distinct nutrient environments they encounter in the digestive tract of the ...
Maria A. Doyle, James I. MacRae, David P. De Souza, Eleanor C. Saunders, Malcolm J. McConville, Vladimir A. Likic   +5 more
openaire   +4 more sources

Anti-leishmanial Activity of Methanolic Extract of Nerium oleander L. against Leishmania major

Medical Laboratory Journal, 2017
Background and Objectives: Leishmaniasis is a public health problem caused by the protozoan Leishmania. Pentavalent antimonials are currently used for treatment of leishmaniasis, but they have serious side effects. Nerium oleander L.
Hamed Noormohammadi, Yahya Maroufi, Mansour Dabirzadeh, Abdolhossein Miri   +3 more
doaj  

Leukocyte Behavior in Mesenteric Microcirculation upon Experimental By Leishmania Spp. in BALB/c Mice

Iranian Journal of Parasitology, 2021
Background: We aimed to determine the cellular recruitment (leukocyte rolling and adhesion) by which the Leishmania (Viannia) braziliensis, L. (Leishmania) amazonensis, and L. (Leishmania) major species in the mesenteric microcirculation of BALB/c mice.
Herintha Coeto Neitzke-Abreu, Rhuan Carlos Souza Caetano, Kárin Rosi Reinhold-Castro, Manoel Sebastião da Costa Lima-Junior, Wagner José Tenório dos Santos, Gessilda de Alcantara Nogueira de Melo, Roberto Kenji Nakamura Cuman, Sandra Mara Alessi Aristides, Thais Gomes Verzignassi Silveira, Maria Valdrinez Campana Lonardoni   +9 more
doaj  

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

Phytotherapy Research, EarlyView.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta, Sonalika Gupta, Gagandeep Kaur, Partha Sarathi Mondal, Milirani Das, Anagha Ranade, Alok Kumar Srivastava, Sachin Kumar, Manoj Kumar Barthwal, Madhu Dikshit   +9 more
wiley   +1 more source

Clinical and Epidemiological Characteristics of Leishmania Species in Isfahan, Iran [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
Background and Objectives: Leishmaniasis is a vector-borne disease that caused by kinetoplastid protozoa of the Leishmania genus. This study aims to investigate the clinical and epidemiologic characteristics of Leishmania species in patients with ...
Azadeh Zolfaghari, Keivan Beheshti-Maal, Ali Mohammad Ahadi, Ramesh Monajemi   +3 more
doaj  

La leishmaniose cutanée des steppes« Étude épidémiologique et typage des souches »

Avicenna Medical Research
La leishmaniose cutanée constitue un important problème de santé publique dans les régions arides et semi-arides d’Algérie, où les modifications environnementales et anthropiques favorisent l’expansion des foyers endémiques.
L Chorfi, K Abdelouahed, A-H Fendri
doaj   +1 more source