Results 61 to 70 of about 9,977 (186)

La leishmaniose cutanée des steppes« Étude épidémiologique et typage des souches »

Avicenna Medical Research
La leishmaniose cutanée constitue un important problème de santé publique dans les régions arides et semi-arides d’Algérie, où les modifications environnementales et anthropiques favorisent l’expansion des foyers endémiques.
L Chorfi, K Abdelouahed, A-H Fendri
doaj   +1 more source

A dhfr-ts- Leishmania major Knockout Mutant Cross-protects against Leishmania amazonensis

Memorias do Instituto Oswaldo Cruz, 1999
E10-5A3 is a dhfr-ts- Leishmania major double knockout auxotrophic shown previously to induce substantial protection against virulent L. major infection in both genetically susceptible and resistant mice.
PST Veras, CI Brodskyn, FMP Balestieri, LAR de Freitas, APS Ramos, ARP Queiroz, A Barral, SM Beverley, M Barral-Netto   +8 more
doaj   +1 more source

Molecular Characterization of Non‐Specific Esophagitis Reveals a Distinct Non‐Eosinophilic Phenotype With Fibrotic Traits

Allergy, EarlyView.
This study comprehensively characterizes non‐specific esophagitis and elucidates eosinophil‐independent fibrosis mechanisms. NSE appears to be a distinct fibrotic phenotype of the esophagus, without any considerable overlap with GERD and other chronic inflammatory disorders such as EoE or lymphocytic esophagitis.
Marc Pfefferle, Darko Stojkov, Dagmar Simon, Emilie Gueguen, Marcin Wawrzyniak, Margaret H. Collins, Mirna Chehade, Evan S. Dellon, Glenn T. Furuta, Ikuo Hirano, Nirmala Gonsalves, Fouad J. Moawad, Luc Biedermann, Alain M. Schoepfer, Alex Straumann, Hans‐Uwe Simon, Thomas Greuter   +16 more
wiley   +1 more source

Investigating the role of the Leishmania (Leishmania) major HASP and SHERP genes during metacyclogenesis in the sand fly vectors, Phlebotomus (Phlebotomus) papatasi and Ph. (Ph.) duboscqi [PDF]

, 2013
Leishmania parasites are the causative agents of a diverse spectrum of infectious diseases termed the leishmaniases. These digenetic parasites exist as intracellular, aflagellate amastigotes in a mammalian host and as extracellular flagellated ...
Doehl, Johannes
core  

Inhibition of trypsin expression in Lutzomyia longipalpis using RNAi enhances the survival of Leishmania [PDF]

, 2009
Background Leishmania parasites must overcome several barriers to achieve transmission by their sand fly vectors. One of the earliest threats is exposure to enzymes during blood meal digestion.
Rod J Dillon, Dillon, Rod J, Hector Diaz-Albiter, Sant'Anna, Mauricio R.V., Sant'anna, Mauricio Rv, Paul A Bates, Diaz-Albiter Hector, Dillon, Rod, Dillon Rod J, Diaz-Albiter, Hector, Mauricio RV Sant'Anna, Bates, Paul, Mubaraki, Murad, Sant'Anna Mauricio RV, Murad Mubaraki, Bates, Paul A, Bates Paul A, Mubaraki Murad   +17 more
core   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

LeishCyc: a biochemical pathways database for Leishmania major [PDF]

BMC Systems Biology, 2009
Abstract Background Leishmania spp. are sandfly transmitted protozoan parasites that cause a spectrum of diseases in more than 12 million people worldwide. Much research is now focusing on how these parasites adapt to the distinct nutrient environments they encounter in the digestive tract of the ...
Maria A. Doyle, James I. MacRae, David P. De Souza, Eleanor C. Saunders, Malcolm J. McConville, Vladimir A. Likic   +5 more
openaire   +3 more sources

Prevalence of Leishmania species among patients with cutaneous leishmaniasis in Qassim province of Saudi Arabia

BMC Public Health, 2019
Background Leishmaniasis is a parasitic infection endemic in more than ninety countries of the world. The cutaneous leishmaniasis (CL) is a most common form of leishmaniasis and it remains to be a major public health issue in Saudi Arabia. This study was
Zafar Rasheed, Ahmed A. Ahmed, Tarek Salem, Mohammed S. Al-Dhubaibi, Ahmad A. Al Robaee, Abdullateef A. Alzolibani   +5 more
doaj   +1 more source

The role of neutrophils in the pathophysiology of inflammatory bowel diseases

Periodontology 2000, EarlyView.
Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens, Ekin Yay‐Kus, Rafael Scaf de Molon, Viorelia Stoica, Peter Rimmer, Josefine Hirschfeld, Asif Jilani Iqbal, Tariq Iqbal, Iain Chapple   +8 more
wiley   +1 more source