Results 21 to 30 of about 5,616,372 (322)
Systems Studies Uncover miR-146a as a Target in Leishmania major Infection Model
ACS Omega, 2020 Leishmaniasis, the second most neglected tropical disease, has been reported to affect approximately 12 million people worldwide. The causative protozoan parasite Leishmania has shown drug resistance to available chemotherapies, owing to which we need to
Prajakta Nimsarkar +2 more
semanticscholar +1 more source
Iranian Journal of Parasitology, 2021 Background: Neglected tropical diseases (NTDs) like zoonotic cutaneous leishmaniasis (ZCL), is a widespread infectious disease with high mortality and morbidity.
Mehdi Najm +7 more
doaj +1 more source
Treatment Outcome of the Drug-resistant Zoonotic Cutaneous Leishmaniasis by Glucantime
Advanced Biomedical Research, 2017 Background: Resistance of Leishmania species to antimonial drugs has increased. Hence, in the present study Leishmania major isolates were collected from patients with resistance phenotype and the presence/absence of resistance to Glucantime was ...
Simindokht Soleimanifard +4 more
doaj +1 more source
Leishmania major: Parasite Interactions Suggesting Sexuality [PDF]
Memorias do Instituto Oswaldo Cruz, 1997 In five experiments, Leishmania (Leishmania) major (MRHO/SU/59/P-strain) grew poorly when seeded in FYTS medium supplemented with 15% fetal calf serum, but presented several peculiar pairs of promastigotes diametrically opposed and attached at their ...
Sousa Maria Auxiliadora de +2 more
doaj +3 more sources
Mixed Mucosal Leishmaniasis Infection Caused by Leishmania tropica and Leishmania major [PDF]
Journal of Clinical Microbiology, 2012 ABSTRACT Mixed infections with different Leishmania species could explain differences in the clinical courses of these infections. On identification of Leishmania parasites from Iranian patients with mucosal leishmaniasis (ML), a patient with both oral and nasal lesions was found to
Sadegh, Shirian +3 more
openaire +2 more sources
Bangladesh Journal of Pharmacology, 2018 Besides its nutritional value as a dietary supplement, Tribulus terrestris is used as a remedy for fertility disorder in Ayurveda and Chinese medicine as well as by modern herbalists.
Salwa Bouabdallah +6 more
doaj +1 more source
Distinct roles in autophagy and importance in infectivity of the two ATG4 cysteine peptidases of leishmania major [PDF]
, 2012 Macroautophagy in Leishmania, which is important for the cellular remodeling required during differentiation, relies upon the hydrolytic activity of two ATG4 cysteine peptidases (ATG4.1 and ATG4.2).
Afonso +58 more
core +1 more source
Frontiers in Immunology, 2018 The absence of tumor necrosis factor (TNF) causes lethal infection by Leishmania major in normally resistant C57BL/6J (B6.WT) mice. The underlying pathogenic mechanism of this fatal disease has so far remained elusive.
Shan-Shan Hu +5 more
semanticscholar +1 more source
Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism. [PDF]
, 1990 BALB/c mice infected with Leishmania major develop fatal, progressive disease, despite an immune response characterized by expansion of CD4+ T cells in the draining lymph nodes.
Dawkins, RS +5 more
core +1 more source
Overview of the organization of protease genes in the genome of Leishmania spp
Parasites & Vectors, 2014 Background The genus Leishmania includes protozoan parasites that are able to infect an array of phlebotomine and vertebrate species. Proteases are related to the capacity of these parasites to infect and survive in their hosts and are therefore ...
Mariana Silva-Almeida +4 more
doaj +1 more source