Results 51 to 60 of about 5,616,372 (322)
Molecular Characterization of Leishmania RNA virus 2 in Leishmania major from Uzbekistan
Genes, 2019 Here we report sequence and phylogenetic analysis of two new isolates of Leishmania RNA virus 2 (LRV2) found in Leishmania major isolated from human patients with cutaneous leishmaniasis in south Uzbekistan.
Yuliya Kleschenko +6 more
semanticscholar +1 more source
Comorbidity of Leishmania major with cutaneous sarcoidosis
Indian Journal of Dermatology, 2014 leishmaniasis infection might manifest as sarcoidosis; on the other hand, some evidences propose an association between sarcoidosis and leishmaniasis. Most of the times, it is impossible to discriminate idiopathic sarcoidosis from leishmaniasis by conventional histopathologic exam.We performed a cross-sectional study to examine the association of ...
Hamideh Moravvej +4 more
openaire +3 more sources
Charaterization of Leishmania major Friedlin Telomeric Terminus [PDF]
Memórias do Instituto Oswaldo Cruz, 2002 Here we have characterized Leishmania major (Friedlin) telomeric terminus (the very end) using recombinants obtained by a vector-adaptor cloning protocol. As in L. donovani, the last nine nucleotides of L. major terminus are 5'-GGTTAGGGT-OH 3', differing from Trypanosoma cruzi and T.
Chiurillo, Miguel Angel +1 more
openaire +4 more sources
Oligopeptidase B deficient mutants of Leishmania major [PDF]
Molecular and Biochemical Parasitology, 2011 Oligopeptidase B is a clan SC, family S9 serine peptidase found in gram positive bacteria, plants and trypanosomatids. Evidence suggests it is a virulence factor and thus therapeutic target in both Trypanosoma cruzi and T. brucei, but little is known about its function in Leishmania. In this study L.
Munday, Jane C. +4 more
openaire +3 more sources
Antileishmanial activity of polycyclic derivatives
Parasite, 2005 33 polycyclic derivatives have been studied and tested on Leishmania donovani and L. major promastigotes. Their antileishmanial activity was assessed in vitro and an assay of their cytotoxicity was realized on human myelomonocytic cell line.
Sarciron M.E. +8 more
doaj +1 more source
Parasite, 2019 Lesion features in cutaneous leishmaniasis (CL) depend on the infecting Leishmania species as well as on host immune reponse. In this study, we evaluated the histological and immunological differences between two forms of CL described in Tunisia ...
Boussoffara Thouraya +6 more
doaj +1 more source
Molecular Microbiology, 2018 Limited knowledge on the exact functions of ergostane‐based sterols has hampered the application of sterol synthesis inhibitors against trypanosomatid parasites.
S. Mukherjee +5 more
semanticscholar +1 more source
Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice [PDF]
, 2009 The small GTPase Rab5 is a key regulator of endosome/phagosome maturation and in intravesicular infections marks a phagosome stage at which decisions over pathogen replication or destruction are integrated.
Aebischer, Toni +9 more
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2019 Leishmaniases are neglected diseases, caused by intracellular protozoan parasites of the Leishmania (L.) genus. Although the principal host cells of the parasites are macrophages, neutrophils are the first cells rapidly recruited to the site of parasites
Rafeh Oualha +5 more
semanticscholar +1 more source
Insights on adaptive and innate immunity in canine leishmaniosis [PDF]
, 2016 Canine leishmaniosis (CanL) is caused by the parasite Leishmania infantum and is a systemic disease, which can present with variable clinical signs, and clinicopathological abnormalities.
Abi Abdallah +19 more
core +4 more sources