Results 61 to 70 of about 5,616,372 (322)

All-Trans Retinoic Acid Promotes an M1- to M2-Phenotype Shift and Inhibits Macrophage-Mediated Immunity to Leishmania major

Frontiers in Immunology, 2017
As key cells, able to host and kill Leishmania parasites, inflammatory monocytes/macrophages are potential vaccine and therapeutic targets to improve immune responses in Leishmaniasis.
N. S. Vellozo, S. T. Pereira-Marques, M. Cabral-Piccin, A. Filardy, F. Ribeiro-Gomes, Thaís S. Rigoni, G. DosReis, M. Lopes   +7 more
semanticscholar   +1 more source

Gene expression in Leishmania is regulated predominantly by gene dosage [PDF]

, 2017
Leishmania tropica, a unicellular eukaryotic parasite present in North and East Africa, the Middle East, and the Indian subcontinent, has been linked to large outbreaks of cutaneous leishmaniasis in displaced populations in Iraq, Jordan, and Syria. Here,
Berriman, Matthew, Beverley, Stephen M., Cotton, James A., Durrant, Caroline, Grigg, Michael E., Iantorno, Stefano A., Khan, Asis, Myler, Peter, Ouellette, Marc, Sacks, David L., Sanders, Mandy J., Warren, Wesley C., Weiss, Louis M.   +12 more
core   +3 more sources

Reinfection in American Cutaneous Leishmaniasis: Evaluation of Clinical Outcomes in the Hamster Model [PDF]

Memorias do Instituto Oswaldo Cruz, 1998
There is no clear understanding of the outcome of reinfection in New World cutaneous leishmaniasis, and its role in the relationship to the development of protection or secondary disease.
Y Osorio, SJ Gonzalez, VL Gama, BL Travi
doaj  

Evidence for regulated expression of Telomeric Repeat-containing RNAs (TERRA) in parasitic trypanosomatids [PDF]

, 2017
The Telomeric Repeat-containing RNAs (TERRA) participate in the homeostasis of telomeres in higher eukaryotes. Here, we investigated the expression of TERRA in Leishmania spp.
Damasceno, Jeziel D., Silva, Gabriel L.A., Tosi, Luiz R.O., Tschudi, Christian   +3 more
core   +1 more source

Canine leishmaniosis caused by Leishmania major and Leishmania tropica: comparative findings and serology

Parasites & Vectors, 2017
BackgroundInfection and clinical disease associated with Leishmania major and Leishmania tropica, two common agents of human cutaneous leishmaniosis, have rarely been reported in dogs.
G. Baneth, D. Yasur-Landau, M. Gilad, Y. Nachum-Biala   +3 more
semanticscholar   +1 more source

Predominance of Leishmania major and rare occurrence of Leishmania tropica with haplotype variability at the center of Iran

Brazilian Journal of Infectious Diseases, 2018
Background: Leishmania major is a causative agent of zoonotic cutaneous leishmaniasis in the center of Iran, Abarkouh district. Molecular characterization and precise incrimination of Leishmania species was carried out to perform controlling measurements
Amir Hossein Zahirnia, Ali Bordbar, Sahar Ebrahimi, Adel Spotin, Somayeh Mohammadi, Seyedeh Maryam Ghafari, Setareh Ahmadvand, Negar Jabbari, Ahmad Reza Esmaeili Rastaghi, Parviz Parvizi   +9 more
doaj   +3 more sources

Isolation and molecular identification of cutaneous leishmaniasis in humans and dogs in middle Euphrates, Iraq [PDF]

Iraqi Journal of Veterinary Sciences
In Iraq, one of the endemic illnesses is cutaneous Leishmaniasis. This study aimed to characterize local isolates of Leishmania tropica and Leishmania major molecularly and determine how closely related they were to reference isolates from nearby nations.
Haider H. Alseady, Sahad M. Al-Dabbagh
doaj   +1 more source

Cinnamic Acid Bornyl Ester Derivatives from Valeriana wallichii Exhibit Antileishmanial In Vivo Activity in Leishmania major-Infected BALB/c Mice. [PDF]

PLoS ONE, 2015
Human leishmaniasis covers a broad spectrum of clinical manifestations ranging from self-healing cutaneous leishmaniasis to severe and lethal visceral leishmaniasis caused among other species by Leishmania major or Leishmania donovani, respectively. Some
Anita Masic, Ana Maria Valencia Hernandez, Sudipta Hazra, Jan Glaser, Ulrike Holzgrabe, Banasri Hazra, Uta Schurigt   +6 more
doaj   +1 more source

Changes to cholesterol trafficking in macrophages by Leishmania parasites infection [PDF]

, 2017
Leishmania spp. are protozoan parasites that are transmitted by sandfly vectors during blood sucking to vertebrate hosts and cause a spectrum of diseases called leishmaniases.
Anderson, Andrade-Neto, Antoine, Bansal, Berman, Blanchette-Mackie, Burack, Carstea, Carvalho, Chakraborty, Chattopadhyay, Collins, Coombs, Coppens, De Cicco, Desvergne, Duclos, Edwards, Ehrenman, Fernandes, Ghosh, Ghosh, Ghosh, Ginger, Ginger, Goldstein, Groener, Hamid, Hart, Ikonen, Infante, Johndrow, Kima, Kima, Kok, Kwon, Lal, Lecoeur, Lippuner, Livak, Majumder, Maxfield, McIntosh, Misslitz, Naureckiene, Neufeld, Osorio y Fortea, Ovalle-Bracho, Paape, Paape, Pereira, Portugal, Pucadyil, Rabhi, Redgrave, Roberts, Rosenzweig, Rub, Russell, Saunders, Sen, Shamshiev, Soares, Sorensen, Tetley, Tewary, Tontonoz, Weinheber   +67 more
core   +2 more sources

Autophagy downstream of endosomal Toll-like receptor signaling in macrophages is a key mechanism for resistance to Leishmania major infection

Journal of Biological Chemistry, 2017
Leishmaniasis is caused by protozoan parasites of the genus Leishmania. In mammalians, these parasites survive and replicate in macrophages and parasite elimination by macrophages is critical for host resistance. Endosomal Toll-like receptors (TLRs) have
L. Franco, Anna K A Fleuri, Natália C. Pellison, Gustavo F. S. Quirino, Catarina V. Horta, R. V. D. de Carvalho, S. Oliveira, D. Zamboni   +7 more
semanticscholar   +1 more source