Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice [PDF]
, 2009 The small GTPase Rab5 is a key regulator of endosome/phagosome maturation and in intravesicular infections marks a phagosome stage at which decisions over pathogen replication or destruction are integrated.
Aebischer, Toni +9 more
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G‐Quadruplexes as Key Transcriptional Regulators in Neglected Trypanosomatid Parasites
ChemBioChem, Volume 24, Issue 12, June 15, 2023., 2023 In this concept article, we discuss the potential roles of DNA G‐quadruplexes (G4s) secondart structures, in modulating the transcriptional control of neglected trypanosomatid parasites, which cause deadly diseases in the poorest populations worldwide.
Ludovica Monti, Marco Di Antonio
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 1982 Utilizando parámetros biométricos de la fase amastigota y el tipo de desarrollo de los parásitos en el flebótomo Lutzomyia townsendi, se han estudiado cuatro aislados de Leishmania obtenidos de pacientes con leishmaniasis cutánea difusa, comparándolos ...
J. V. Scorza, O. Delgado
doaj +1 more source
Leishmania infantum and Leishmania braziliensis : differences and similarities to evade the innate immune system [PDF]
, 2016 Visceral leishmaniasis is a severe form of the disease, caused by Leishmania infantum in the New World. Patients present an anergic immune response that favors parasite establishment and spreading through tissues like bone marrow and liver.
Bernardes, Daniela M. +5 more
core +2 more sources
Leishmania amazonensis promastigotes present two distinct modes of nucleus and kinetoplast segregation during cell cycle. [PDF]
, 2015 : Here, we show the morphological events associated with organelle segregation and their timing in the cell cycle of a reference strain of Leishmania (L.) amazonensis promastigotes, the main causative agent of Tegumentary leishmaniasis in the Americas ...
Cano, Maria Isabel Nogueira +7 more
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Cutaneous leishmaniasis in germfree, gnotobiotic, and conventional mice
Revista do Instituto de Medicina Tropical de São Paulo, 1987 Cutaneous leishmaniasis was much more severe in conventional than in gnotobiotic mice as revealed by macro and microscopic examination. An inoculum of Leishmania mexicana amazonensis was used.
Enio Cardillo Vieira +6 more
doaj +1 more source
Native rodent species are unlikely sources of infection for Leishmania (Viannia) braziliensis along the Transoceanic Highway in Madre de Dios, Peru. [PDF]
, 2014 An estimated 2.3 million disability-adjusted life years are lost globally from leishmaniasis. In Peru's Amazon region, the department of Madre de Dios (MDD) rises above the rest of the country in terms of the annual incidence rates of human leishmaniasis.
Conrad, Patricia A +7 more
core +4 more sources
Intra- and interspecific polymorphisms ofLeishmania donovani andL. tropica minicircle DNA [PDF]
, 1994 A pair of degenerate polymerase chain reaction (PCR) primers (LEI-1, TCG GAT CC[C,T] [G,C]TG GGT AGG GGC GT; LEI-2, ACG GAT CC[G,C] [G,C][A,C]C TAT [A,T]TT ACA CC) defining a 0.15-kb segment ofLeishmania minicircle DNA was constructed.
AJ Magill +16 more
core +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 1984 Del estúdio de 51 stocks de Leishmania aislados de pacientes humanos de leishmaniasis cutaneomucosa en Três Braços, Bahia, Brasil, los autores describen, en detalle, el análisis de los dos únicos stocks de L.
César Augusto Cuba Cuba +2 more
doaj +3 more sources
Interdisciplinary Perspectives on Infectious Diseases, 2014 American cutaneous leishmaniasis includes a spectrum of clinical forms localized cutaneous, diffuse cutaneous, and mucocutaneous leishmaniasis which can be caused by different strains of Leishmania belonging to the L. mexicana or L.
Amalia Monroy-Ostria +4 more
doaj +1 more source