Results 21 to 30 of about 4,221 (205)

BALB/c mice deficient in CD4(+) T cell IL-4R alpha expression control Leishmania mexicana load although female but not male mice develop a healer phenotype [PDF]

open access: yes, 2011
Immunologically intact BALB/c mice infected with Leishmania mexicana develop non-healing progressively growing lesions associated with a biased Th2 response while similarly infected IL-4R alpha-deficient mice fail to develop lesions and develop a robust ...
Owain R Millington   +29 more
core   +1 more source

Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice [PDF]

open access: yes, 2009
The small GTPase Rab5 is a key regulator of endosome/phagosome maturation and in intravesicular infections marks a phagosome stage at which decisions over pathogen replication or destruction are integrated.
Paape, Daniel   +31 more
core   +1 more source

Morfometria amastigotica y desarrollo de cuatro aislados de Leishmania mexicana pifanoi de Venezuela em Lutzomyia townsendi Amastigote morphometry and development of 4 isolated of Leishmania mexicana pifanoi of Venesuela in Lutzomyia townsendi

open access: yesMemorias do Instituto Oswaldo Cruz, 1982
Utilizando parámetros biométricos de la fase amastigota y el tipo de desarrollo de los parásitos en el flebótomo Lutzomyia townsendi, se han estudiado cuatro aislados de Leishmania obtenidos de pacientes con leishmaniasis cutánea difusa, comparándolos ...
J. V. Scorza, O. Delgado
doaj   +1 more source

The role of surface glycoconjugates in Leishmania midgut attachment examined by competitive binding assays and experimental development in sand flies [PDF]

open access: yes, 2013
SUMMARY Binding of promastigotes to the sand fly midgut epithelium is regarded as an essential part of the Leishmania life cycle in the vector. Among Leishmania surface molecules putatively involved in attachment to the sand fly midgut, two GPI-anchored ...
Jecna, Lucie   +13 more
core   +1 more source

Heparin modulates the endopeptidase activity of Leishmania mexicana cysteine protease cathepsin L-Like rCPB2.8 [PDF]

open access: yes, 2013
Cysteine protease B is considered crucial for the survival and infectivity of the Leishmania in its human host. Several microorganism pathogens bind to the heparin-like glycosaminoglycans chains of proteoglycans at host-cell surface to promote their ...
Gesteira, Tarsis F.   +45 more
core   +1 more source

Cutaneous leishmaniasis in germfree, gnotobiotic, and conventional mice

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1987
Cutaneous leishmaniasis was much more severe in conventional than in gnotobiotic mice as revealed by macro and microscopic examination. An inoculum of Leishmania mexicana amazonensis was used.
Enio Cardillo Vieira   +6 more
doaj   +1 more source

Synthetic glycovaccine protects against the bite of leishmania-infected sand flies [PDF]

open access: yes, 2006
Leishmaniasis is a vectorborne disease transmitted to human and other mammalian hosts by sand fly bite. In the present study, we show that immunization with Leishmania mexicana promastigote secretory gel (PSG) or with a chemically defined synthetic ...
Bates, Paul A.   +14 more
core   +1 more source

Leishmania mexicana: aspectos taxonómicos y rareza de la infección humana en Três Braços, Bahia, Brasil

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 1984
Del estúdio de 51 stocks de Leishmania aislados de pacientes humanos de leishmaniasis cutaneomucosa en Três Braços, Bahia, Brasil, los autores describen, en detalle, el análisis de los dos únicos stocks de L.
César Augusto Cuba Cuba   +2 more
doaj   +3 more sources

ITS1 PCR-RFLP Diagnosis and Characterization of Leishmania in Clinical Samples and Strains from Cases of Human Cutaneous Leishmaniasis in States of the Mexican Southeast

open access: yesInterdisciplinary Perspectives on Infectious Diseases, 2014
American cutaneous leishmaniasis includes a spectrum of clinical forms localized cutaneous, diffuse cutaneous, and mucocutaneous leishmaniasis which can be caused by different strains of Leishmania belonging to the L. mexicana or L.
Amalia Monroy-Ostria   +4 more
doaj   +1 more source

Studies on the relationship between lectin binding carbohydrates and different strains of Leishmania from the New World

open access: yesMemorias do Instituto Oswaldo Cruz, 1982
The culture forms of L. mexicana pifanoi (LRC L-90), L. mexicana mexicana (LRC L-94, M-379); L. braziliensis braziliensis (LRC L-77, L-1, M-2903, H-LSS) and L.
J. Schottelius   +1 more
doaj   +1 more source

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