Inhibition of growth of Leishmania mexicana mexicana by Leishmania mexicana amazonensis during "in vitro" co-cultivation Inibição do crescimento de Leishmania mexicana mexicana por Leishmania mexicana amazonensis durante o co-cultivo "in vitro" [PDF]
Memorias do Instituto Oswaldo Cruz, 1987 Inhibition of one Leishmania subspecies by exometabolites of another subspecies, a phenomenon not previously reported, is suggested by our recent observations in cell cloning experiments with Leishmania mexicana mexicana and Leishmania mexicana ...
Raquel S. Pacheco +2 more
doaj +5 more sources
Mechanisms of Immune Evasion, Dissemination, and Persistence in Leishmania amazonensis Infection. [PDF]
Parasite ImmunolABSTRACT Leishmania amazonensis is one of the etiological agents of cutaneous leishmaniasis in its localised form. Moreover, this parasite can cause more severe disease conditions, such as diffuse and disseminated cutaneous leishmaniasis. The development of more severe clinical manifestations is associated with the parasite's ability to establish a ...
Portugal AB +3 more
europepmc +2 more sources
Leishmaniasis Transmission Risk at the Forest-Peridomestic Interface in an Area of Southern Sinaloa, Mexico: Entomological, Molecular, and Climatic Evidence. [PDF]
J Parasitol ResLeishmaniasis, caused by Leishmania spp. and transmitted by phlebotomine sand flies, affects almost 1,000,000 people annually across more than 90 countries. In Mexico, growing evidence of locally acquired transmission in northwestern states makes ecoepidemiological work increasingly urgent.
Tostado JJR +7 more
europepmc +2 more sources
Peptides as a Therapeutic Alternative Against Leishmaniasis: A Scoping Review. [PDF]
Chem Biol Drug DesThis scoping review of 79 studies identified 231 antimicrobial peptides with anti‐Leishmania activity, including natural‐derived and synthetic peptides (inspired by natural sources or developed through rational design). Most were evaluated in vitro against promastigote and/or amastigote forms, with synthetic peptides showing a more promising effect ...
da Veiga Oliveira ME +3 more
europepmc +2 more sources
Structural basis of secreted acid phosphatase polymerization in the Leishmania parasite. [PDF]
Protein SciAbstract Enzymes that assemble into filaments typically transition between protomeric and polymeric states in response to cellular conditions. In contrast, the secreted acid phosphatase (SAP) of Leishmania, one of the most abundant extracellular glycoproteins produced by the parasite and regarded as a major virulence factor in the neglected tropical ...
Bose P +4 more
europepmc +2 more sources
Isolation of an enriched plasma membrame subpellicular microtubule fraction of Leishmania mexicana amazonensis [PDF]
Memorias do Instituto Oswaldo Cruz, 1980 A cell fractionation procedure previously developed for Trypanosoma cruzi was applied to isolated the plasma membrane of promastigotes of Leishania mexicana amazonensis.
Solange L. Timm +6 more
doaj +4 more sources
Interleukin- 2 production during murine infection by Leishmania mexicana amazonensis [PDF]
Memorias do Instituto Oswaldo Cruz, 1986 Highly susceptible BALB/c mice, resistant C57B1/6 and their F1 progeny (BDF1) were infected subcutaneously in the foot pad with Leishmania mexicana amazonenesis. At various times after infection, spleen or draining popliteal lymph node cells were assayed
Manoel Barral-Netto +2 more
doaj +4 more sources
PubChem BioAssays 1063: A Poorly Exploited Source of New Antileishmanial Compounds
Journal of Parasitology ResearchPubChem Bioassays (AID 1063) reported the in vitro testing of 196,141 compounds against Leishmania major promastigotes. Although these results have been publicly available since 2008, limited efforts on further testing of some of these compounds has been
Sergio Sifontes-Rodríguez +7 more
doaj +2 more sources
Leishmania mexicana amazonensis isolated from a patient with fatal mucosal leishmaniasis [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 1985 Faculdade de Medicina (FMD)
Raimunda N. Sampaio +4 more
doaj +5 more sources
Cutaneous Leishmaniasis Mimicking a Nasal Tumor: A Case Report. [PDF]
Case Rep Infect DisLeishmaniasis is a disease caused by Leishmania protozoa that is transmitted to the patient by sand flies. Depending on the Leishmania species, the disease can present with cutaneous, mucosal, or multiorgan involvement. Cutaneous leishmaniasis can present with diverse clinical manifestations mimicking other diseases.
Hekmat M +4 more
europepmc +2 more sources