Leishmania mexicana amazonensis isolated from a patient with fatal mucosal leishmaniasis [PDF]
Faculdade de Medicina ...
Raimunda N. Sampaio +4 more
doaj +10 more sources
PubChem BioAssays 1063: A Poorly Exploited Source of New Antileishmanial Compounds [PDF]
PubChem Bioassays (AID 1063) reported the in vitro testing of 196,141 compounds against Leishmania major promastigotes. Although these results have been publicly available since 2008, limited efforts on further testing of some of these compounds has been
Sergio Sifontes-Rodríguez +7 more
doaj +3 more sources
Inhibition of growth of Leishmania mexicana mexicana by Leishmania mexicana amazonensis during "in vitro" co-cultivation Inibição do crescimento de Leishmania mexicana mexicana por Leishmania mexicana amazonensis durante o co-cultivo "in vitro" [PDF]
Inhibition of one Leishmania subspecies by exometabolites of another subspecies, a phenomenon not previously reported, is suggested by our recent observations in cell cloning experiments with Leishmania mexicana mexicana and Leishmania mexicana ...
Raquel S. Pacheco +2 more
doaj +5 more sources
Isolation of an enriched plasma membrame subpellicular microtubule fraction of Leishmania mexicana amazonensis [PDF]
A cell fractionation procedure previously developed for Trypanosoma cruzi was applied to isolated the plasma membrane of promastigotes of Leishania mexicana amazonensis.
Solange L. Timm +6 more
doaj +4 more sources
Interleukin- 2 production during murine infection by Leishmania mexicana amazonensis [PDF]
Highly susceptible BALB/c mice, resistant C57B1/6 and their F1 progeny (BDF1) were infected subcutaneously in the foot pad with Leishmania mexicana amazonenesis. At various times after infection, spleen or draining popliteal lymph node cells were assayed
Manoel Barral-Netto +2 more
doaj +4 more sources
The Genome Sequence of Leishmania (Leishmania) amazonensis: Functional Annotation and Extended Analysis of Gene Models [PDF]
We present the sequencing and annotation of the Leishmania (Leishmania) amazonensis genome, an etiological agent of human cutaneous leishmaniasis in the Amazon region of Brazil. L.
Fernando Real +2 more
exaly +3 more sources
Destruction of Leishmania mexicana amazonensis amastigotes within macrophages by lysosomotropic amino acid esters. [PDF]
Leishmania amastigotes parasitize almost exclusively the mononuclear phagocytes of mammals. The organisms survive and multiply within acidified vacuoles (parasitophorous vacuoles; p.v.) akin to phagolysosomes. Certain amino acid esters are known to accumulate in and disrupt lysosomes.
M, Rabinovitch +2 more
exaly +3 more sources
In silico predicted epitopes from the COOH-terminal extension of cysteine proteinase B inducing distinct immune responses during
Background Leishmania parasites have been reported to interfere and even subvert their host immune responses to enhance their chances of survival and proliferation.
Pereira Bernardo AS +8 more
doaj +3 more sources
Structure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensis [PDF]
The antiprotozoal compound 1,5-di(4-amidinophenoxy)pentane (pentamidine) and 36 of its analogs were screened for in vitro activity against Leishmania mexicana amazonensis clone 669 C4S (MHOM/BR/73/M2269) and Plasmodium falciparum clones W2 (Indochina III/CDC) and D6 (Sierra Leone I/CDC).
Dennis E Kyle
exaly +3 more sources
Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions [PDF]
Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication.
Adem, E +19 more
core +10 more sources

