Results 11 to 20 of about 4,221 (205)

Experimental infection of Lutzomyia longipalpis fed on a patient with cutaneous leishmaniasis due to Leishmania mexicana amazonensis [PDF]

Memorias do Instituto Oswaldo Cruz, 1986
The authors were able to infect phlebotomine sandflies on a human case of American Cutaneous Leishmaniasis by feeding females of Lutzomyia longipalpis on a patient with a lesion due to Leishmania mexicana amazonensis.Os autores lograram infectar ...
Leonidas M. Deane, Elizabeth Ferreira Rangel, Manoel Paes-Oliveira, Gabriel Grimaldi Junior, Hooman Momen, Nataly de Souza, Eduardo D. Wermelinger, André F. Barbosa   +7 more
doaj   +2 more sources

Leishmania mexicana amazonensis: heterogeneity in 5-nucleotidase and peroxidase activities of mononuclear phagocytes during in vivo and in vitro infection Leishmania mexicana amazonensis: heterogeneidade da 5’-Nucleotidase e da peroxidase em fagócitos mononucleares durante infecção in vivo e in vitro [PDF]

Memorias do Instituto Oswaldo Cruz, 1988
The degree of maturation of cells of the Mononuclear Phagocyte System (MPS), during in vivo and in vitro infection by Leishmania mexicana amazonenesis, was evaluated in this study.
Suzana Côrte-Real, Gabriel Grimaldi Junior, Maria de Nazareth Leal de Meirelles   +2 more
doaj   +2 more sources

Flagellates in the Malpighian tubules of laboratory-bred Lutzomyia longipalpis fed on a hamster experimentally infected with Leishmania mexicana amazonensis [PDF]

Memorias do Instituto Oswaldo Cruz, 1985
As a preparatory stage for a study aiming at identifying the species and subspecies of local Leishmania in naturally infected sandflies through immunoradiometric assay with monoclonal antibodies, we tried to obtain experimental infections of ...
Elizabeth Ferreira Rangel, Leonidas M. Deane, Gabriel Grimaldi Filho, Nataly A. de Souza, Eduardo D. Wermelinger, André F. Barbosa   +5 more
doaj   +2 more sources

PubChem BioAssays 1063: A Poorly Exploited Source of New Antileishmanial Compounds

Journal of Parasitology Research
PubChem Bioassays (AID 1063) reported the in vitro testing of 196,141 compounds against Leishmania major promastigotes. Although these results have been publicly available since 2008, limited efforts on further testing of some of these compounds has been
Sergio Sifontes-Rodríguez, Susana Meneses-Gómez, Alma Reyna Escalona-Montaño, Daniel Andrés Sánchez-Almaraz, Ofelia Pérez-Olvera, Aranza Regina Cañón Rosas, Pedro Zuriel Cruz Bautista, María Magdalena Aguirre-García   +7 more
doaj   +2 more sources

Leishmania isoenzyme polymorphisms in Ecuador: Relationships with geographic distribution and clinical presentation [PDF]

BMC Infectious Diseases, 2006
Background Determinants of the clinical presentation of the leishmaniases are poorly understood but Leishmania species and strain differences are important.
Mimori Tatsuyuki, Barroso Paola A, Korenaga Masataka, Gomez Eduardo A, Kato Hirotomo, Uezato Hiroshi, Marco Jorge D, Armijos Rodrigo X, Calvopina Manuel, Cooper Philip J, Nonaka Shigeo, Hashiguchi Yoshihisa   +11 more
doaj   +2 more sources

Mechanisms of Immune Evasion, Dissemination, and Persistence in Leishmania amazonensis Infection. [PDF]

Parasite Immunol
ABSTRACT Leishmania amazonensis is one of the etiological agents of cutaneous leishmaniasis in its localised form. Moreover, this parasite can cause more severe disease conditions, such as diffuse and disseminated cutaneous leishmaniasis. The development of more severe clinical manifestations is associated with the parasite's ability to establish a ...
Portugal AB, DaMatta RA, da Cunha Júnior EF, Wanderley JLM.   +3 more
europepmc   +2 more sources

Peptides as a Therapeutic Alternative Against Leishmaniasis: A Scoping Review. [PDF]

Chem Biol Drug Des
This scoping review of 79 studies identified 231 antimicrobial peptides with anti‐Leishmania activity, including natural‐derived and synthetic peptides (inspired by natural sources or developed through rational design). Most were evaluated in vitro against promastigote and/or amastigote forms, with synthetic peptides showing a more promising effect ...
da Veiga Oliveira ME, Dyminski Parente Ribeiro E, Guenther OHP, Tomiotto-Pellissier F.   +3 more
europepmc   +2 more sources

Structural basis of secreted acid phosphatase polymerization in the Leishmania parasite. [PDF]

Protein Sci
Abstract Enzymes that assemble into filaments typically transition between protomeric and polymeric states in response to cellular conditions. In contrast, the secreted acid phosphatase (SAP) of Leishmania, one of the most abundant extracellular glycoproteins produced by the parasite and regarded as a major virulence factor in the neglected tropical ...
Bose P, Dahan I, Upcher A, Zalk R, Grossman-Haham I.   +4 more
europepmc   +2 more sources

Leishmaniose cutânea na Amazônia: registro do primeiro caso humano de infecção mista, determinado por duas espécies distintas de Leishmnias: Leishmania brasiliensis e Leishmania mexicana amazonensis Cutaneous leishmaniasis in Amazonia: the first record of a case of cutaneous leishmaniasis caused by two different parasites: Leishmania braziliensis braziliensis and Leishmania mexicana amazonensis [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 1984
Fez-se o registro, na Amazônia, do primeiro caso humano de infecção cutânea mista determinada por duas espécies distintas de Leishmania: a Leishmania braziliensis braziliensis e a Leishmania mexicana amazonensis.
F. T. Silveira, R. Lainson, J. J. Shaw, R. da S. M. Ribeiro   +3 more
doaj   +3 more sources

Leishmaniasis Transmission Risk at the Forest-Peridomestic Interface in an Area of Southern Sinaloa, Mexico: Entomological, Molecular, and Climatic Evidence. [PDF]

J Parasitol Res
Leishmaniasis, caused by Leishmania spp. and transmitted by phlebotomine sand flies, affects almost 1,000,000 people annually across more than 90 countries. In Mexico, growing evidence of locally acquired transmission in northwestern states makes ecoepidemiological work increasingly urgent.
Tostado JJR, Ureta HC, Avendaño JIT, Moreno JMZ, Higareda CER, Guevara LIP, Medina AIA, Montoya EHT.   +7 more
europepmc   +2 more sources