Results 31 to 40 of about 108,835 (233)

Loop-Mediated Isothermal Amplification Allows Rapid, Simple and Accurate Molecular Diagnosis of Human Cutaneous and Visceral Leishmaniasis Caused by Leishmania infantum When Compared to PCR

Microorganisms, 2021
Loop-mediated isothermal amplification allows the rapid, sensitive and specific amplification of DNA without complex and expensive equipment. We compared the diagnostic performance of Loopamp™ Leishmania Detection Kit (Eiken Chemical Co., Ltd., Tokyo ...
Ana Victoria Ibarra-Meneses, Carmen Chicharro, Carmen Sánchez, Emilia García, Sheila Ortega, Joseph Mathu Ndung’u, Javier Moreno, Israel Cruz, Eugenia Carrillo   +8 more
doaj   +1 more source

The potential role and apoptotic profile of three medicinal plant extracts on Leishmania tropica by MTT assay, macrophage model and flow cytometry analysis

Parasite Epidemiology and Control, 2021
Introduction: Treatment of leishmaniasis with conventional synthetic drugs is a major global challenge. This study was designed to explore the leishmanicidal activity and apoptotic profile of three leaf extracts on Leishmania tropica stages. Methods: The
Mozhde Ilaghi, Iraj Sharifi, Fariba Sharififar, Fatemeh Sharifi, Razieh Tavakoli Oliaee, Zahra Babaei, Manzume Shamsi Meimamandi, Alireza Keyhani, Mehdi Bamorovat   +8 more
doaj   +1 more source

Increasing incidence of zoonotic visceral leishmaniasis on Crete, Greece [PDF]

, 2009
To determine whether the incidence of canine leishmaniasis has increased on Crete, Greece, we fitted infection models to serodiagnostic records of 8,848 dog samples for 1990–2006.
Adler, Andrew J. Sutton, Connor Carson, Courtenay, Courtenay, Hadjinicolaou, Hertig, Ioanna Ascoksilaki, Ippokratis Messaritakis, Ivovic, Leger, Leger, Leger, Maria Antoniou, Nikos Kanavakis, Orin Courtenay, Quinnell, Sutton, Vasiliki Christodoulou, Williams   +19 more
core   +4 more sources

Anti-Leishmanial and Immunomodulatory Effects of Epigallocatechin 3-O-Gallate on Leishmania tropica: Apoptosis and Gene Expression Profiling

Iranian Journal of Parasitology, 2019
Background: Pentavalent antimonials such as meglumine antimoniate (MA, Glucantime), are the first-line treatment against leishmaniasis, but at present, they have basically lost their efficacy. This study was aimed to explore epigallocatechin 3-O-gallate (
Morteza SADUQI, Iraj SHARIFI, Zahra BABAEI, Alireza KEYHANI, Mahshid MOSTAFAVI, Maryam HAKIMI PARIZI, Mahdiyeh GHASEMIAN, Mehdi BAMOROVAT, Fatemeh SHARIFI, Mohammad Reza AFLATOONIAN, Fariba SHARIFIFAR, Pooya GHASEMI NEJAD, Ahmad KHOSRAVI, Ehsan SALARKIA, Rajender S. VARMA   +14 more
doaj   +1 more source

Leishmaniasis [PDF]

The Lancet, 1999
In 1903, Leishman and Donovan separately described the protozoan now called Leishmania donovani in splenic tissue from patients in India with the life-threatening disease now called visceral leishmaniasis. Almost a century later, many features of leishmaniasis and its major syndromes (ie, visceral, cutaneous, and mucosal) have remained the same; but ...
openaire   +2 more sources

Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions [PDF]

, 2016
Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication.
Adem, E, Cruz Cervera, E, Diro, E, Getahun, M, Hailu, A, Kropf, P, Lemma, M, Melkamu, R, Mengesha, B, Mesfin, G, Modolell, M, Muller, I, Munder, M, Skhedy, Z, Tajebe, F, Takele, Y, Van der Auwera, G, Yardley, V, Yeshanew, A, Yizengaw, E   +19 more
core   +3 more sources

Leishmania: Responding to environmental signals and challenges without regulated transcription

Computational and Structural Biotechnology Journal, 2020
Here we describe the non-canonical control of gene expression in Leishmania, a single-cell parasite that is responsible for one of the major neglected tropical diseases.
Janne Grünebast, Joachim Clos
doaj   +1 more source

Rapid Detection of Leishmania infantum Infection in Dogs: Comparative Study Using an Immunochromatographic Dipstick Test, Enzyme-Linked Immunosorbent Assay, and PCR [PDF]

, 2002
Current zoonotic visceral leishmaniasis (ZVL) control programs in Brazil include the culling of Leishmania infantum-infected reservoir dogs, a strategy that has failed to prevent a rise of canine and human ZVL cases over the past decade.
Bruce Alex, Bruce Alex, Clive R. Davies, Clive R. Davies, J. Clin Microbiol, Richard Reithinger, Richard Reithinger, Rupert J. Quinnell, Rupert J. Quinnell   +8 more
core   +3 more sources

Periungual leishmaniasis [PDF]

Anais Brasileiros de Dermatologia, 2012
The vast majority of cases of cutaneous leishmaniasis are represented by limb injuries. A female patient, white, presented an ulcer with infiltrated borders located on the fourth finger of the left hand following occupational exposure in an area of native forest.
Gomes, Ciro Martins, Morais, Orlando Oliveira de, Leite, Anglya Samara Silva, Soares, Killarney Ataíde, Motta, Jorgeth de Oliveira Carneiro da, Sampaio, Raimunda Nonata Ribeiro   +5 more
openaire   +4 more sources

Incidence of Trypanosoma cruzi infection in two Guatemalan communities.

, 2004
The prevalence of human infection by Trypanosoma cruzi was assessed using an enzyme-linked immunosorbent assay (ELISA) in a serological survey in 1998 of 2 rural communities (SMH and PS) in Guatemala.
Davies, C, Lines, J, Monroy, C, Paz-Bailey, G, Rodas, A, Rosales, R, Tabaru, R   +6 more
core   +1 more source