Results 131 to 140 of about 157,834 (170)

Lentivirus Vectors in β-Thalassemia

2012
Patients with β-thalassemia major require lifelong transfusions and iron chelation, regardless of the type of causative mutations (e.g., β⁰, β(E)/β⁰). The only available curative therapy is allogeneic hematopoietic transplantation, although most patients do not have an HLA-matched, geno-identical donor, and those who do still risk graft-versus-host ...
Emmanuel, Payen, Charlotte, Colomb, Olivier, Negre, Yves, Beuzard, Kathleen, Hehir, Philippe, Leboulch   +5 more
openaire   +2 more sources

Role of Macrophages in Lentivirus Infections

1988
Publisher Summary This chapter discusses the role of macrophages in lentivirus infections. Cells of the mononuclear phagocytic system are important hosts for the replication of lentiviruses. This host–virus relationship has been studied most extensively in lentivirus infection in ruminants in which the macrophage plays two roles: (1) as a host cell ...
O, Narayan, M C, Zink
openaire   +2 more sources

Microinjecting Lentivirus into Mouse Embryos

Cold Spring Harbor Protocols, 2018
This protocol describes the injection of lentivirus into the perivitelline space of fertilized oocytes. Embryos usually survive lentiviral injection well because only the zona is pierced.
openaire   +2 more sources

Lentivirus

2006
Yichen Lu, Max Essex
openaire   +1 more source

Lentivirus infection of macrophages.

Immunology series, 1994
The ovine and caprine lentiviruses infect monocytes, and the viral DNA is integrated into the cellular DNA. The provirus remains silent until the monocyte matures into a macrophage. Intrinsic to this maturation is the induction of a class of immediate early genes in the monocyte that includes the transcription factors JUN and FOS.
J E, Clements, M C, Zink, O, Narayan, D H, Gabuzda   +3 more
openaire   +1 more source

Optimized protocol for high‐titer lentivirus production and transduction of primary fibroblasts

Journal of Basic Microbiology, 2021
Ming Yang, Wei Chen, Wei Han
exaly  

Lentivirus vectors for gene therapy

Biochemical Society Transactions, 1999
A M, Lever, J F, Kaye, E, McCann, D, Chadwick, N, Dorman, J, Thomas, J, Zhao   +6 more
openaire   +2 more sources

Lentivirus tropism and pathogenesis

Immunology Letters, 1999
openaire   +2 more sources

Lentivirus Mediated Pancreatic Beta-Cell-Specific Insulin Gene Therapy for STZ-Induced Diabetes

Molecular Therapy, 2021
Salih Sanlioglu, Mustafa Kemal Balcı, Thomas Griffith   +2 more
exaly  

Autologous, lentivirus‐modified, T‐rapa cell “micropharmacies” for lysosomal storage disorders

EMBO Molecular Medicine, 2022
Jeffrey A Medin, Maria Fuller, Charles Rupar   +2 more
exaly