Results 71 to 80 of about 173,548 (215)
Sources of Error in Mammalian Genetic Screens
G3: Genes, Genomes, Genetics, 2016 Genetic screens are invaluable tools for dissection of biological phenomena. Optimization of such screens to enhance discovery of candidate genes and minimize false positives is thus a critical aim.
Laura Magill Sack +4 more
doaj +1 more source
shRNA lentivirus vector constructs used.
, 2014 shRNA lentivirus vector constructs used.
Claire Shannon-Lowe (166060) +6 more
core +1 more source
, 2023 Most significantly enriched pathways analysis of cancer driver genes in shDMKN lentivirus (KD) and GFP lentivirus (NC) control in C8161 cell.
Saber Imani (6680012) +9 more
core +1 more source
, 2007 BackgroundTowards gene therapy treatment of patients with neutropenia, characterized by neutrophil counts MethodsRats were injected intramuscularly (IM) with 24 x 10(6) and 9 x 10(6) infectious units (IU) of a VSV-G-pseudotyped self-inactivating (SIN ...
Waldron, L. +4 more
core +1 more source
Specific Inhibition of SRC Kinase Impairs Malignant Glioma Growth In Vitro and In Vivo
Molecular Therapy: Nucleic Acids, 2012 Malignant glioma is a severe cancer with a poor prognosis. Local occurrence and rare metastases of malignant glioma make it a suitable target for gene therapy. Several studies have demonstrated the importance of Src kinase in different cancers.
Hanna Stedt +7 more
doaj +1 more source
Impact of Veterinary Vaccines on Human Health and Probable Challenges
Acta Veterinaria Eurasia, 2021 Md. Mehadi Hasan SOHAG +1 more
doaj +1 more source
Lentivirus-transduced human iPSCs differentiate to multipotent neural precursor cells.
, 2016 (A) Representative micrographs of human iPSCs transduced with a lentiviral vector containing the Photinus pyralis luciferase gene and puromycin resistance cassette.
Craig M. Walsh (2839346) +7 more
core +1 more source
Development of Viral Vectors for Use in Cardiovascular Gene Therapy
Viruses, 2010 Cardiovascular disease represents the most common cause of mortality in the developed world but, despite two decades of promising pre-clinical research and numerous clinical trials, cardiovascular gene transfer has so far failed to demonstrate convincing
Paul A. Kingston +3 more
doaj +1 more source
Lentivirus-mediated Atg3 overexpression in SKM-1 cells.
, 2016 (A) At 72 h post-transfection, SKM-1 cells transfected with FLAG-tagged ATG3-overexpressing vector and empty vector were detected by fluorescence and light microscopy. Western blotting of Atg3 protein (40 kD band) in SKM-1 cells detected by Atg3 (B and C)
Lin Zhuang (389736) +6 more
core +1 more source
An Efficient Method for Isolation of Plasmid DNA for Transfection of Mammalian Cell Cultures
Methods and Protocols, 2020 In this article, we present several protocols that describe the steps from cloning and obtaining a large amount of pure plasmid DNA to generation of lentiviruses based on these constructs.
Daniel V. Kachkin +3 more
doaj +1 more source