Results 61 to 70 of about 173,548 (215)
Lentivirus-induced immune dysregulation [PDF]
Veterinary Immunology and Immunopathology, 2008 FIV/HIV infections are associated with an early robust humoral and cellular anti-viral immune response followed by a progressive immune suppression that eventually results in AIDS. Several mechanisms responsible for this immune dysfunction have been proposed including cytokine dysregulation, immunologic anergy and apoptosis, and inappropriate ...
Mary B, Tompkins, Wayne A, Tompkins
openaire +2 more sources
Lentivirus-mediated NIBP knockdown in HCT116 cells.
, 2017 Control un-transfected HCT116 cells had higher NIBP protein expression compared to NIBP-knockdown HCT116 cells. Cells transfected with an empty vector (NC) had high NIBP expression, similar to the control un-transfected HCT116 cells, as determined by ...
Mengbin Qin (3710482) +6 more
core +1 more source
A transitional endogenous lentivirus from the genome of a basal primate and implications for lentivirus evolution [PDF]
Proceedings of the National Academy of Sciences, 2008 Lentiviruses chronically infect a broad range of mammalian species and have been transmitted from primates to humans, giving rise to multiple outbreaks of HIV infection over the past century. Although the circumstances surrounding these recent zoonoses are becoming clearer, the nature and timescale of interaction between ...
Gifford, R +5 more
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Frontiers in Immunology, 2019 Genetic engineering is an important tool for redirecting the function of various types of immune cells and their use for therapeutic purpose. Although NK cells have many beneficial therapeutic features, genetic engineering of immune cells for targeted ...
Rafijul Bari +12 more
doaj +1 more source
Study shRNA lentivirus vectors.
, 2015 a NA—not availableStudy shRNA lentivirus vectors.
Bo Ding (210928) +4 more
core +1 more source
Primate and Feline Lentivirus Vector RNA Packaging and Propagation by Heterologous Lentivirus Virions [PDF]
Journal of Virology, 2001 ABSTRACT Development of safe and effective gene transfer systems is critical to the success of gene therapy protocols for human diseases. Currently, several primate lentivirus-based gene transfer systems, such as those based on human and simian immunodeficiency viruses (HIV/SIV), are being tested; however, their use in humans raises safety ...
M T, Browning +3 more
openaire +2 more sources
Vaccines, 2014 The ability to predict the conditions under which antibodies protect against viral infection would transform our approach to vaccine development. A more complete understanding is needed of antibody protection against lentivirus infection, as well as the ...
Elissa J. Schwartz, Robert J. Smith?
doaj +1 more source
Membranes, 2023 Recent approval of several viral-vector-based therapeutics has led to renewed interest in the development of more efficient bioprocessing strategies for gene therapy products.
Akshay S. Chaubal, Andrew L. Zydney
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, 2023 The relative contribution of somatically point mutation variants between DMKN-shRNA lentivirus (KD) and GFP lentivirus (NC) control in MUM-2B cell line.
Saber Imani (6680012) +9 more
core +1 more source
Veterinární Medicína, 2001 In this study, recombinant histidine tagged p25 capsid protein of Maedi-Visna virus was developed. Part of the viral genome coding p25 protein was positioned downstream and in frame with a metal binding domain in pRSET-B vector.
D. Molinková
doaj +1 more source