Results 71 to 80 of about 51,346 (240)
Small Ruminant Lentiviruses: Maedi-Visna & Caprine Arthritis and Encephalitis [PDF]
, 2015 Maedi-visna and caprine arthritis and encephalitis are economically important viral diseases that affect sheep and goats. These diseases are caused by a group of lentiviruses called the small ruminant lentiviruses (SRLVs). SRLVs include maedivisna virus (
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Advanced Science, EarlyView.The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan +10 more
wiley +1 more source
mBio, 2016 There has been extraordinary progress in understanding the roles of lentiviral accessory proteins in antagonizing host antiviral defense proteins. However, the precise primary function of the accessory gene Vpr remains elusive.
Oliver I. Fregoso, Michael Emerman
doaj +1 more source
Functional Crosstalk between Human Papillomaviruses and Lentiviruses [PDF]
, 2016 Human papillomaviruses (HPVs) and human immunodeficiency virus‐1 (HIV‐1) are human pathogens of high biomedical significance worldwide. Interestingly, increasing epidemiological evidence indicates that individuals with active HPV infections possess an ...
Pryszlak, Anna Marta
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Advanced Science, EarlyView.A schematic model summarizing GNA15's mechanism in mediating macrophage M2 polarization and Gemcitabine resistance. ABSTRACT The complexity of pancreatic ductal adenocarcinoma (PDAC) progression, coupled with the lack of effective immunotherapy, underscores the imperative to deepen our understanding of its mechanisms and identify suitable immune ...
Weihui Guo +8 more
wiley +1 more source
Bio-Protocol, 2019 Robust and efficient gene expression control enables the study of a gene’s function in the central nervous system. Advances in CRISPR-based technology provide new avenues not only for gene editing, but for complex transcriptional control.
Katherine Savell +2 more
doaj +1 more source
A Potent Postentry Restriction to Primate Lentiviruses in a Yinpterochiropteran Bat
mBio, 2020 Bats are primary reservoirs for multiple lethal human viruses, such as Ebola, Nipah, Hendra, rabies, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome-related coronavirus (MERS-CoV), and, most recently, SARS-CoV-2.
James H. Morrison +5 more
doaj +1 more source
Advanced Science, EarlyView.Hypoxia triggers a dual mechanism for BHLHE40 upregulation: reactive oxygen species (ROS)‐dependent post‐translational modification and hypoxia‐inducible factor (HIF)‐dependent transcriptional activation. Under hypoxic conditions, mitochondrial BHLHE40 accumulates and senses ROS via cysteine thiol oxidation and disulfide‐linked homodimer formation ...
Jia Liu +13 more
wiley +1 more source
Transmission of small ruminant lentiviruses
, 2004 Small ruminant lentiviruses (SRLV) are classical slow retroviruses causing chronic inflammatory disease in a variety of target organs. The routes of transmission have been investigated and a large body of evidence has accumulated over many years.
Berriatua, Eduardo +6 more
core +1 more source
Serological evidence and spatial analysis of small ruminant lentiviruses in herds in Maranhão, Brazil [PDF]
, 2020 Caprine arthritis encephalitis and Maedi-Visna are lentiviruses affecting goats and sheep, respectively. Despite the literature having studies about these diseases, there is a constant demand and the need to study the health status of flocks that exploit
Sousa, Leandro Henrique Veiga de +6 more
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