Results 131 to 140 of about 319,296 (404)
Folia Histochemica et Cytobiologica, 2008 Leptin and its receptor may be engaged in pathogenesis of breast cancer among various human tumors. In vitro investigations showed leptin-mediated escalation of estrogen synthesis and boosted activity of estrogen receptor ERalpha.
Stanislaw Sulkowski +4 more
doaj +3 more sources
Hepatic gene expression profiling reveals key pathways involved in leptin-mediated weight loss in ob/ob mice. [PDF]
PLoS ONE, 2010 BACKGROUND: Leptin, a cytokine-like protein, plays an important role in the regulation of body weight through inhibition of food intake and stimulation of energy expenditure.
Ashok Sharma +6 more
doaj +1 more source
The Bidirectional Relationship Between Obstructive Sleep Apnea and Metabolic Disease [PDF]
, 2018 Obstructive sleep apnea (OSA) is a common sleep disorder, effecting 17% of the total population and 40–70% of the obese population (1, 2). Multiple studies have identified OSA as a critical risk factor for the development of obesity, diabetes, and ...
Arble, Deanna M., Framnes, Sarah N.
core +3 more sources
Identification of targets of leptin action in rat hypothalamus.
Journal of Clinical Investigation, 1996 The hypothesis that leptin (OB protein) acts in the hypothalamus to reduce food intake and body weight is based primarily on evidence from leptin-deficient, ob/ob mice.
M. Schwartz +4 more
semanticscholar +1 more source
Hopfian $\ell$-groups, MV-algebras and AF C$^*$-algebras [PDF]
arXiv, 2015 An algebra is said to be hopfian if it is not isomorphic to a proper quotient of itself. We describe several classes of hopfian and of non-hopfian unital lattice-ordered abelian groups and MV-algebras. Using Elliott classification and $K_0$-theory, we apply our results to other related structures, notably the Farey-Stern-Brocot AF C$^*$-algebra and all
arxiv
Lean ZSF1 rats in basic research on heart failure with preserved ejection fraction
ESC Heart Failure, Volume 12, Issue 2, Page 1474-1478, April 2025.Abstract Aims ZSF1 obese rats harbouring two mutant leptin receptor alleles (Leprcp and Leprfa) develop metabolic syndrome and heart failure with preserved ejection fraction (HFpEF), making them a widely used animal model in cardiometabolic research.
Petra Büttner +10 more
wiley +1 more source
Serum lipid peroxidation and leptin levels in male and female type 2 diabetic patients in Gorgan (south east of Caspian Sea), Iran [PDF]
, 2009 Background: The aim of the present study was to determinate the possible relationship between serum leptin and lipid peroxidation in male and female type 2 diabetic patients in Gorgan, Iran.
Badeleh, M.T., Marjani, A., Veghari, G.
core
Impact of birth weight and gender on early postnatal hypothalamic energy balance regulatory gene expression in the young lamb [PDF]
, 2013 Peer ...
Adam, C. L. +5 more
core +1 more source
Toward molecular neuroeconomics of obesity [PDF]
arXiv, 2011 Because obesity is a risk factor for many serious illnesses such as diabetes, better understandings of obesity and eating disorders have been attracting attention in neurobiology, psychiatry, and neuroeconomics. This paper presents future study directions by unifying (i) economic theory of addiction and obesity (Becker and Murphy, 1988; Levy 2002 ...
arxiv
ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira +12 more
wiley +1 more source