Results 171 to 180 of about 2,380,940 (353)

Serum Leptin Receptor and the rs1137101 Variant of the LEPR Gene Are Associated with Bladder Cancer. [PDF]

Biomolecules, 2023
Alfaqih MA, Elsalem L, Nusier M, Mhedat K, Khader Y, Ababneh E.   +5 more
europepmc   +1 more source

A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury

Neuroprotection, EarlyView.
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley   +1 more source

Association of Leptin and Leptin receptor Gene polymorphisms with Insulin resistance in pregnant women: A cross-sectional study [version 3; peer review: 3 approved]

F1000Research
Introduction Leptin, along with its receptor, are linked with mechanisms affecting a diverse array of pregnancy-specific pathologies that include gestational diabetes and intrauterine growth restriction.
Usha Adiga, Tirthal Rai, Nandit Banawalikar   +2 more
doaj  

Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction

, 1999
Liquan Cai, Jeffrey M. Friedman
openalex   +1 more source

Immunohistochemical and ultrastructural localization of leptin and leptin receptor in human white adipose tissue and differentiating human adipose cells in primary culture. [PDF]

, 2000
Stefan R. Bornstein, Mones Abu‐Asab, Annegret Glasow, G Päth, Hans Hauner, Maria Tsokos, George P. Chrousos, Werner A. Scherbaum   +7 more
openalex   +1 more source

Phytochemical Nanoparticles for the Treatment of Neurological Disorders

Phytochemical Analysis, EarlyView.
ABSTRACT Neurological disorders impose a significant burden on the healthcare systems. The latest published data by WHO indicated that stroke was the second leading cause of death globally in 2020, with Alzheimer's disease (AD) and other dementias in the seventh position.
Touraj Ehtezazi, Satyajit D. Sarker
wiley   +1 more source

Angiotensin AT1A receptors on leptin receptor–expressing cells control resting metabolism

Journal of Clinical Investigation, 2017
Kristin E. Claflin, Jeremy A. Sandgren, A. Lambertz, Benjamin J Weidemann, Nicole K. Littlejohn, C. Burnett, Nicole A. Pearson, D. Morgan, K. Gibson-Corley, K. Rahmouni, J. Grobe   +10 more
semanticscholar   +1 more source

Fabricating Microfluidic Co‐Cultures of Immortalized Cell Lines Uncovers Robust Design Principles for the Simultaneous Formation of Patterned, Vascularized, and Stem Cell‐Derived Adipose Tissue

Small, EarlyView.
Murphy et al present an optimized co‐culture protocol for immortalized cell line vasculogenesis. Here, immortalized co‐cultures form reproducible microvessel networks across 31‐days, while gradient microchips enable simultaneous mesenchymal stem cell (MSC) adipogenesis and endothelial cell (EC) vasculogenesis.
Ashley R. Murphy, Rose Ann Franco, Mark C. Allenby   +2 more
wiley   +1 more source

Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db/db Mice

Cell, 1996
Hong Chen, O. Charlat, L. Tartaglia, E. Woolf, Xun Weng, S. J. Ellis, N. Lakey, J. Culpepper, Karen J More, R. Breitbart, G. Duyk, R. Tepper, J. Morgenstern   +12 more
semanticscholar   +1 more source

Modeling Adipokine and Insulin‐Mediated Crosstalk Between Adipocytes and Beta Cells Using Flow‐Enabled Microfluidics

Small, EarlyView.
A microfluidic system with a µTesla pump is developed to model adipocyte–beta cell crosstalk under flow. Elevated glucose and insulin enhanced adipocyte secretion of IL‐6, TNF‐α, and adiponectin, while IL‐6 stimulated beta‐cell insulin secretion. This feed‐forward loop mimics obesity‐driven beta cell dysfunction, offering new insights into Type 2 ...
Mohamad Orabi, Mehdi Sh Yeganeh, Tae‐Hwa Chun, Joe Fujiou Lo   +3 more
wiley   +1 more source