Implication of Leptin-Signaling Proteins and Epstein-Barr Virus in Gastric Carcinomas. [PDF]
We investigated the clinicopathological implications of leptin-signaling proteins and Epstein-Barr virus (EBV)-infection status in gastric carcinomas. Immunohistochemistry for leptin signalling-related proteins (leptin, leptin-receptor, pSTAT3, ERK, pAkt,
Euno Choi +7 more
doaj +1 more source
Normal leptin expression, lower adipogenic ability, decreased leptin receptor and hyposensitivity to Leptin in Adolescent Idiopathic Scoliosis. [PDF]
Leptin has been suggested to play a role in the etiology of Adolescent Idiopathic Scoliosis (AIS), however, the leptin levels in AIS girls are still a discrepancy, and no in vitro study of leptin in AIS is reported.
Guoyan Liang +8 more
doaj +1 more source
Leptin receptor in boar spermatozoa [PDF]
SummaryLeptin is active in both metabolism and reproduction. In fact, it seems to exert an inhibitory action on gonadal functions by reducing testosterone production. The presence of leptin in human and boar seminal plasma and in human spermatozoa has been demonstrated; recently, leptin receptors (Ob‐R) have been localized in human spermatozoa, thus ...
DE AMBROGI, MARCO +3 more
openaire +2 more sources
The Effects of Laparoscopic Sleeve Gastrectomy on the Parameters of Leptin Resistance in Obesity
Obesity is a growing public health problem worldwide. Bariatric surgical procedures achieve the most sustainable and efficacious outcomes in the treatment of morbid obesity.
Tagleb S. Mazahreh +7 more
doaj +1 more source
Monitoring the Expression of Leptin Receptor in Avian Model
In this study we carried the expression of leptin receptor in organs and abdominal fat of broiler chickens. The leptin receptor is a member of the class I cytokine receptor family, also known as the gpl30 receptor family, although unlike many other ...
Ľubica Mrázová +2 more
doaj
Discovery of the elusive leptin in birds: identification of several 'missing links' in the evolution of leptin and its receptor. [PDF]
Leptin is a pleiotropic protein best known for regulation of appetite and fat storage in mammals. While many leptin orthologs have been identified among vertebrates, an authentic leptin in birds has remained elusive and controversial.
Jeremy W Prokop +10 more
doaj +1 more source
Objective: Data on effects of vitamins, hormones and neurotrophic factors on the etiology of attention deficit hyperactivity disorder (ADHD) and major depressive disorder (MDD) in children is limited.
Dilsad Yildiz Miniksar +1 more
doaj +1 more source
Monitoring leptin activity using the chicken leptin receptor [PDF]
We report on the construction of a leptin bioassay based on the activation of chicken leptin receptor in cultured cells. A human embryonic kidney (HEK)-293 cell line, stably transfected with the full-length cDNA of chicken leptin receptor together with a STAT3-responsive reporter gene specifically responded to recombinant human and Xenopus leptins. The
Gideon, Hen +6 more
openaire +2 more sources
Leptin, soluble leptin receptor, and free leptin index in patients with metabolic syndrome
Aim. To assess the levels of leptin, its soluble receptor, and index of the formation of free leptin in metabolic syndrome (MS). Materials and methods. The study included 110 individuals with obesity and overweight.
Elena N. Smirnova, Sofia G. Shulkina
doaj +1 more source
Leptin induces IL-6 expression through OBRl receptor signaling pathway in human synovial fibroblasts. [PDF]
BACKGROUND: Leptin, an adipocyte-secreted hormone that centrally regulates weight control, may exert proinflammatory effects in the joint, depending on the immune response.
Wei-Hung Yang +6 more
doaj +1 more source

