Results 221 to 230 of about 76,631 (314)

Prime editing-mediated correction of the leptin receptor in muscle cells of db/db mice. [PDF]

Biotechnol J
Lee KE, Xu Y, Geng B, Kim J, Kellon N, He Z, Zhang Z, Li D, Gouchoe DA, Zhu H.   +9 more
europepmc   +1 more source

A Review of the Effects of Maternal and Paternal Obesity on Neurodevelopmental Disorders and Related Neurobiology in Rodent and Human Offspring

Obesity Reviews, EarlyView.
ABSTRACT Obesity is one of the most prevalent health problems worldwide, and global obesity rates continue to rise. Consequently, rates of obesity in expecting mothers and fathers have also increased. The Developmental Origins of Health and Disease (DOHaD) hypothesis postulates that early‐life exposure to adverse environmental conditions contributes to
Hannah Chadwick, Victorio Bambini Junior, Neil Dawson, Cheryl A. Hawkes   +3 more
wiley   +1 more source

Hypomethylated leptin receptor reduces cerebral ischaemia-reperfusion injury by activating the JAK2/STAT3 signalling pathway. [PDF]

J Int Med Res
Wang X, Wang Z, Liu S, Feng Y, Zhang T, Wu Z, Huang J, Zhao W.   +7 more
europepmc   +1 more source

Metabolic Syndrome and Obesity‐related cancer Risk and Survival: An Umbrella Review of Systematic Reviews With Meta‐analysis of Observational Studies

Obesity Reviews, EarlyView.
ABSTRACT Introduction Metabolic syndrome (MetS) may be associated with obesity‐related cancer (ORC) owing to shared risk factors like physical inactivity, insulin resistance, gut microbiome dysfunction, and inflammation. We conducted an umbrella review of systematic reviews with meta‐analysis to synthesize the evidence on the association between MetS ...
Maci Winn, Prasoona Karra, Ryzen Benson, Svenja Pauleck, Nathorn Chaiyakunapruk, Win Khaing, Sajesh K. Veettil, Mary M. McFarland, Tallie Casucci, Yizhe Xu, Siwen Hu‐Lieskovan, Michelle Litchman, Mary Playdon, Sheetal Hardikar   +13 more
wiley   +1 more source

Leptin Receptor Deficiency Impairs Lymph Node Development and Adaptive Immune Response. [PDF]

J Immunol
Cardani-Boulton A, Sung SJ, Petri WA, Hahn YS, Braciale TJ.   +4 more
europepmc   +1 more source

The Complex Relation of Branched‐Chain Amino Acids and Inflammation in the Obesity and Diabetes Context

Obesity Reviews, EarlyView.
ABSTRACT In a scenario with increasing cases of obesity and diabetes worldwide, branched‐chain amino acids (BCAA) metabolism has become an important factor in the understanding of these pathologies. More recently, its chronic high plasma levels have been postulated, alongside glucose, inflammatory factors, and other molecules, as an important ...
Bernardo Starling‐Soares, Monique Macedo Coelho, Bruna Guerra Campolina, Camila Kümmel Duarte, Tatiani Uceli Maioli   +4 more
wiley   +1 more source

Multidisciplinary Therapy to Target Obesity and Its Complications in Adult Population: A Narrative Review

Obesity Reviews, EarlyView.
ABSTRACT Obesity as a chronic and multifactorial disease requires a multidisciplinary team acting together in a holistic multitarget intervention. Multidisciplinary therapy targeting obesity and its complications includes physical exercise, nutritional, and behavior counseling.
Ana Raimunda Dâmaso, Flávia Campos Corgosinho, Deborah Cristina Landi Masquio, Nayra Figueiredo, Fabiana Kattah, Cintia Cercato, Lian Tock, Raquel Munhoz da Silveira Campos   +7 more
wiley   +1 more source

Effect of <i>Aeromonas hydrophila</i> infection on leptin receptor overlapping transcript expression in <i>Rana amurensis</i>. [PDF]

Anim Biotechnol
Sun Y, Wu T, Chen Z, Ren H, Liu Y, Liu P, Zhao W.   +6 more
europepmc   +1 more source

Maternal Obesity and MicroRNAs in Breast Milk: Implications for Infant Developmental Programming

Obesity Reviews, EarlyView.
ABSTRACT This review explores the relationship between maternal obesity and alterations in the expression of microRNAs (miRNAs) in breast milk, highlighting how these changes may influence the developmental programming of the infant. Evidence suggests that maternal obesity can affect the bioactive composition of breast milk, including miRNA profiles ...
Gyslane M. Santos, Fabíola Isabel Suano de Souza, Luciana P. Pisani   +2 more
wiley   +1 more source

Leptin receptor neurons in the ventral premammillary nucleus modulate emotion-induced insomnia. [PDF]

Cell Discov
Yuan XS, Xiang Z, Jiang JB, Yuan F, Zhang MT, Zhang KY, Chen ZY, Qu WM, Li WS, Huang ZL.   +9 more
europepmc   +1 more source