Results 31 to 40 of about 2,380,940 (353)
Leptin, soluble leptin receptor, and free leptin index in patients with metabolic syndrome
Aim. To assess the levels of leptin, its soluble receptor, and index of the formation of free leptin in metabolic syndrome (MS). Materials and methods. The study included 110 individuals with obesity and overweight.
Elena N. Smirnova, Sofia G. Shulkina
doaj +1 more source
The Leptin Receptor Complex: Heavier Than Expected?
Under normal physiological conditions, leptin and the leptin receptor (ObR) regulate the body weight by balancing food intake and energy expenditure.
J. Wauman, L. Zabeau, J. Tavernier
semanticscholar +1 more source
Leptin and Soluble Leptin Receptor in Follicular Fluid [PDF]
Previous studies suggest that follicular fluid leptin levels predict successful assisted reproduction. The relationship between intrafollicular leptin and the soluble leptin receptor, ovarian hormones, and oocyte quality was examined to determine potential factors contributing to this finding.Follicular fluid leptin, soluble leptin receptor, hormones ...
Kathleen Heist+3 more
openaire +3 more sources
Estimation of Leptin and Leptin Receptor Concentrations in Seminal Plasma of Primary Infertile Men
Background: There are many sources for Leptin secretion, and it is activated by binding with its receptor known as leptin receptor, that play a role in male infertility.
Ruqaya M. AL-Barzinji+1 more
doaj +1 more source
Leptin and visfatin are implicated in breast cancer risk but studies accounting for bioavailability of leptin are sparse. Reports on the association of leptin gene (LEP) and leptin receptor gene (LEPR) polymorphisms with breast cancer are also ...
Chrishani Rodrigo+5 more
semanticscholar +1 more source
Kinetics of Leptin Binding to the Q223R Leptin Receptor
Studies in human populations and mouse models of disease have linked the common leptin receptor Q223R mutation to obesity, multiple forms of cancer, adverse drug reactions, and susceptibility to enteric and respiratory infections. Contradictory results cast doubt on the phenotypic consequences of this variant.
Verkerke, Hans+5 more
openaire +4 more sources
Evaluation of the leptin receptor in human spermatozoa
Background Leptin, a 167 amino acid peptide hormone, profoundly effects reproduction exerting its biological effects via interaction with the leptin receptor (ObR) which is widely expressed on peripheral tissues.
Ghaedi Kamran+8 more
doaj +1 more source
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode+16 more
wiley +1 more source
Associations between serum leptin levels, hyperlipidemia, and cholelithiasis in dogs. [PDF]
Leptin and its receptor play several physiological roles in the canine gallbladder, and the dysregulation of leptin might play a role in the pathogenesis of gallbladder diseases such as gallbladder mucocele.
Sungin Lee, Oh-Kyeong Kweon, Wan Hee Kim
doaj +1 more source
The Role of the Adipokine Leptin in Immune Cell Function in Health and Disease
Leptin is a critical mediator of the immune response to changes in overall nutrition. Leptin is produced by adipocytes in proportion to adipose tissue mass and is therefore increased in obesity. Despite having a well-described role in regulating systemic
K. Kiernan, Nancie J. MacIver
semanticscholar +1 more source