Results 271 to 280 of about 72,689 (297)

Improvement of Leptin Resistance

Yeungnam University Journal of Medicine, 2013
Leptin, a 16-kDa cytokine, is secreted by adipose tissue in response to the surplus of fat store. Thereby, the brain is informed about the body's energy status. In the hypothalamus, leptin triggers specific neuronal subpopulations (e.g., POMC and NPY neurons) and activates several intracellular signaling events, including the JAK/STAT, MAPK, PI3K, and ...
openaire   +1 more source

[Insulin resistance, role of leptin and leptin receptor].

Nihon rinsho. Japanese journal of clinical medicine, 2000
Leptin, the obese gene product, is an adipocyte-derived satiety factor which is involved in the regulation of food intake and energy expenditure. Obesity often accompanies insulin resistance and high levels of leptin. In in vitro studies, leptin has been reported to increase fatty acid oxidation and decrease fatty acid synthesis in adipocytes and ...
M, Shintani, Y, Ogawa, K, Nakao
openaire   +1 more source

Leptin, leptin resistance and endothelial dysfunction in pre-eclampsia.

Cellular and molecular biology (Noisy-le-Grand, France), 2003
Pre-eclampsia, or pregnancy-induced hypertension, is a major cause of maternal and fetal morbidity and mortality complicating 7-10% of pregnancies. Although mechanisms underlying pre-eclampsia are not well understood, endothelial dysfunction is considered to underscore many of the pre-eclamptic manifestations including hypertension, proteinuria and ...
Cindy M, Anderson, Jun, Ren
openaire   +1 more source

Leptin, Adiponectin, and Insulin Resistance

Angiology, 2011
Maria, Sarigianni, Apostolos, Tsapas, Konstantinos, Paletas   +2 more
openaire   +2 more sources

Leptin Resistance and Obesity

2014
Leptin direnci ve obezite leptin reseptörlerinde düşme, maximal leptin sinyal kapasitesi ve diyetle indükte obeziteye duyarlılıktaki artış ile belirmektedir. Öz de artan leptinin obeziteye katkısı leptin direncine dayanmaktadır. Leptin direnci daha fazla obezite ile yıkıcı bir döngüye dönüşmektedir.
openaire   +1 more source

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

Nature, 2001
Michael A Cowley, James L Smart, Marcelo Rubinstein   +2 more
exaly  

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Nature, 2002
Yasuhiko Minokoshi, Young-Bum Kim, David Carling   +2 more
exaly  

Reversing leptin resistance

Nature Reviews Drug Discovery, 2009
openaire   +1 more source

The weight of leptin in immunity

Nature Reviews Immunology, 2004
Antonio La Cava, Giuseppe Matarese
exaly  

Leptin-regulated endocannabinoids are involved in maintaining food intake

Nature, 2001
Vincenzo Di Marzo, Zoltán Járai, Richard D Palmiter   +2 more
exaly