Results 11 to 20 of about 274,618 (211)

Late onset leptomeningeal and whole spine metastasis from supratentorial Glioblastoma multiforme: An uncommon manifestation of a common tumor

Journal of Craniovertebral Junction and Spine, 2016
Glioblastoma multiforme (GBM) is one of the most common and aggressive primary brain tumors, composing 12-20% of all the intracranial tumors in adults with a highly malignant course and average life expectancy of approximately 12-14 months following ...
Divyam Sharma, Anshul Gupta, Gurupal S Dhillon, Satnam Singh Chhabra   +3 more
doaj   +2 more sources

Hemidystonia as an Initial Manifestation of Leptomeningeal Metastasis [PDF]

Journal of Movement Disorders, 2009
A 76-year-old woman gradually developed action dystonia of the left hand and foot. Leptomeningeal metastasis of the right fronto-parietal area associated with gastric adenocarcinoma was found on the brain magnetic resonance imaging (MRI) and positron emission tomography (PET) studies.
Hyun-Jung Jung, Seong-Min Choi, Byeong-Chae Kim   +2 more
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The anatomic basis of leptomeningeal metastasis

Journal of Experimental Medicine
Leptomeningeal metastasis (LM), or spread of cancer to the cerebrospinal fluid (CSF)–filled space surrounding the central nervous system, is a fatal complication of cancer. Entry into this space poses an anatomical challenge for cancer cells; movement of cells between the blood and CSF is tightly regulated by the blood–CSF barriers.
Morgan E. Freret, Adrienne Boire
openaire   +3 more sources

Hemangioblastoma with late leptomeningeal metastasis: a case report [PDF]

Journal of Medical Case Reports, 2023
Background Hemangioblastoma of the central nervous system is an uncommon benign neoplasm, with about 25% of cases in patients with von Hippel–Lindau disease. The incidence of metastasis is rare, particularly in patients without von Hippel–Lindau disease.
Spencer J. Poiset, Aneesh Reddy, Catherine M. Tucker, Lawrence C. Kenyon, Kevin D. Judy, Wenyin Shi   +5 more
doaj   +3 more sources

Only the strong survive: therapeutic selective pressure drives medulloblastoma leptomeningeal metastasis

Molecular Oncology
Medulloblastoma (MB) is the most common malignant tumor in the central nervous system in childhood and regularly metastasizes to the leptomeninges following radiation therapy.
Francis Y. He, Adrienne Boire
doaj   +2 more sources

Long-Term Response of Lorlatinib to Leptomeningeal Metastasis in Patients with Anaplastic Lymphoma Kinase Fusion Positive Non-Small Lung Cancer: A Case Report [PDF]

Case Reports in Oncology
Introduction: Patients with anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer (NSCLC) are at increased risk of central nervous system (CNS) metastasis at initial diagnosis and throughout treatment.
Yutaka Fujiwara, Katsuhiro Masago, Reiko Matsuzawa, Teppei Yamaguchi, Naohiro Watanabe, Junichi Shimizu, Eiichi Sasaki, Yoshitsugu Horio   +7 more
doaj   +2 more sources

Advanced NSCLC with leptomeningeal metastasis: Diagnostic and therapeutic challenges: A case report

Radiology Case Reports
Lung cancer, particularly non-small lung cancer (NSCLC), is one of the most common malignant tumors worldwide and is associated with high mortality in advanced stages. Lung adenocarcinoma is the most frequent NSCLC subtype.
Gana Odeh, Dana Foqha, Mohammed Abu Kamesh, Jihad Hamaida   +3 more
doaj   +2 more sources

Craniospinal irradiation in the treatment of chemotherapy refractory leptomeningeal metastasis from breast cancer: A case report

Cancer Reports, 2022
Background Leptomeningeal carcinomatosis is a relatively uncommon complication of solid tumors that is associated with significant morbidity and mortality.
Daniel Tesolin, Dimitrios Vergidis, Kevin Ramchandar   +2 more
doaj   +2 more sources

Leptomeningeal metastasis of multiple myeloma [PDF]

Arquivos de Neuro-Psiquiatria, 2021
Cristiane Máximo da Silva, Jamison Menezes de Souza, Roberto Queiroz dos Santos, Mariana Spitz   +3 more
doaj   +6 more sources

Management of leptomeningeal metastasis in breast cancer [PDF]

Clinical Neurology and Neurosurgery, 2018
Leptomeningeal metastasis (LM), which occurs when malignant cells spread to the central nervous system, is becoming an increasingly common complication in patients with breast cancer. Diagnosis and treatment of LM is challenging. Moreover, prognosis of patients with LM is poor, with a median survival of 6 months after diagnosis.
Hazem I, Assi, Tala, Mahmoud, Fadi S, Saadeh, Haidar, El Darsa   +3 more
openaire   +3 more sources