Results 41 to 50 of about 274,618 (211)

Durable remission of leptomeningeal metastases from hormone-responsive prostate cancer

open access: yes, 2011
Prostate cancer is rarely associated with leptomeningeal metastasis. An 87-year-old man with a history of prostate cancer presented with leptomeningeal metastasis. He received hormonal therapy with leuprolide.
Santosh Kesari   +9 more
core   +1 more source

Triphasic waves in leptomeningeal metastases and cycling alternating pattern of encephalopathy during sleep

open access: yesEpileptic Disorders, EarlyView.
Abstract Background Triphasic waves (TWs), now termed generalized periodic discharges with triphasic morphology, may be mistaken for nonconvulsive status epilepticus (NCSE), particularly in critically ill patients. Changes in vigilance over time can help distinguish encephalopathic patterns from ictal activity.
Philippe Gélisse, Arielle Crespel
wiley   +1 more source

Anaplastic extramedullary cervical ependymoma with leptomeningeal metastasis.

open access: yes, 2023
We present a rare extramedullary ependymoma with diffuse spinal metastatic disease, and review the previous reports of extramedullary spinal ependymomas. Ependymomas are the most common intramedullary spinal cord tumor in adults.
Sumner, HM   +5 more
core   +1 more source

The diagnostic value of contrast-enhanced fluid-attenuated inversion recovery fat saturation magnetic resonance imaging in leptomeningeal metastasis of lung cancer

open access: yes肿瘤影像学, 2020
Objective: To investigate the diagnostic value of T2-weighted imaging fluid-attenuated inversion recovery fat saturation (T2WI-FLAIR-FS) enhanced scanning in lung cancer with leptomeningeal metastasis. Methods: Routine T1 weighted imaging fat saturation (
CHAO Hua   +5 more
doaj  

Visual loss as the initial manifestation of an ignored disseminated prostate cancer: A case report

open access: yesAmerican Journal of Ophthalmology Case Reports, 2022
Purpose: To present a rare case of advanced disseminated prostate cancer with bilateral visual loss as the initial manifestation of the disease. Observations: A 55-year-old man referring progressive visual blurring for the last 6 months and painless ...
Alejandra B. Miranda   +3 more
doaj   +1 more source

Craniofacial Resection for Advanced Cutaneous Squamous Cell Carcinoma: Results From the 2nd International Collaborative Case‐Series

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Robust outcome data for anterior skull base cutaneous squamous cell carcinoma (cSCC) are limited, particularly as emerging therapies reshape management. We evaluated survival and prognostic factors following craniofacial resection. Methods Retrospective multi‐institutional case‐series (1995–2015) of patients who underwent skull base
Michael J. C. Schachtel   +52 more
wiley   +1 more source

Long‐Term Clinical Response After Low‐Dose and Short‐Duration Cemiplimab Therapy in a Patient With Xeroderma Pigmentosum in Nepal

open access: yesJEADV Clinical Practice, EarlyView.
Capsule Summary Xeroderma pigmentosum (XP) is associated with a high risk of multiple and aggressive cutaneous squamous cell carcinomas (CSCCs). The immune checkpoint inhibitor cemiplimab has been approved in advanced, unresectable, and/or metastatic CSCCs.
Sudip Parajuli   +5 more
wiley   +1 more source

Successful osimertinib rechallenge without concomitant corticosteroids after osimertinib-induced pneumonitis

open access: yesRespiratory Medicine Case Reports
A 60-year-old woman was diagnosed with cT4N3M1c stage IVB lung adenocarcinoma with epidermal growth factor receptor mutation of exon19 deletion. After one month of treatment with osimertinib, a cough and diffuse ground glass opacities were observed in ...
Taisuke Ito   +5 more
doaj   +1 more source

Mass Spectrometry Imaging–Guided Proteomics, an Emerging Frontier in Spatial Biology

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Spatial heterogeneity is a defining feature of tissue organization, yet conventional proteomic analysis provides limited information about the spatial origins of identified proteins. Spatially guided proteomics addresses this limitation by using tissue imaging techniques to select regions of interest (ROIs) for localized analysis by liquid ...
Kenneth Weke   +4 more
wiley   +1 more source

PROTAC EZH2 degrader overcomes podophyllotoxin derivatives-based regimens resistance in refractory SCLC with leptomeningeal metastasis

open access: yes, 2023
Leptomeningeal metastases (LM) of small cell lung cancer (SCLC) are highly detrimental occurrences with severe neurological disorders and extremely poor prognosis without effective treatment.
Minxing Shi (17699814)
core   +1 more source

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