Results 51 to 60 of about 274,618 (211)

Research Progress of Lung Cancer with Leptomeningeal Metastasis

Chinese Journal of Lung Cancer, 2014
Leptomeningeal metastases is one of the most serious complications of lung cancer, the patients with poor prognosis. Leptomeningeal metastasis in patients with lack specificity of clinical manifestations.
Chunhua MA, Rong JIANG, Jinduo LI, Bin WANG, Liwei SUN, Yuan LV   +5 more
doaj   +1 more source

Boron‐embedded multifunctional nanoplatform toward potential combined boron neutron capture therapy and immunomodulation in glioma

Smart Molecules, EarlyView.
A brain‐targeting multifunctional nanoplatform (DM&Ce6@COF‐Ang) was engineered by employing boron‐enriched APTES‐COF‐1 as both the therapeutic boron agent and the nanocarrier co‐delivery of DMXAA and Ce6. This nanoplatform achieved synergistic tumor‐specific boron delivery, real‐time pharmacokinetic monitoring, and immunomodulation.
Yiming Liu, Xuejian Wang, Bangjian Li, Kun Shao, Jianlong Su, Yang Wang, Lin Cheng, Zhihao Wu, JinRong Li, Guanyi Zhang, Xu Wang, Yuxuan Zhang, Yuanhao Liu, Guangzhe Li   +13 more
wiley   +1 more source

Molecular heterogeneity and prognostic biomarkers in primary meningeal melanocytic tumors

Brain Pathology, EarlyView.
Integrated molecular profiling reveals biological heterogeneity among primary meningeal melanocytic tumors, identifying intermediate‐grade PMMT subgroups with distinct recurrence risk. Molecular alterations including SF3B1 mutations and chromosome 8q gains support prognostic stratification, while PRKAR1A alterations and chromosome 17/21q losses aid ...
Rosina Paterra, Monica Patanè, Anna Stroppa, Gianluca Marucci, Serena Ammendola, Sofia Asioli, Valeria Barresi   +6 more
wiley   +1 more source

Leptomeningeal metastasis mimicking temporal arteritis

Neurosciences, 2004
We report a case of recent onset headache, sudden mono-ocular blindness and a high erythrocyte sedimentation rate as a manifestation of leptomeningeal metastasis from undiagnosed carcinoma of the breast, mimicking temporal arteritis.
Elgaili M, Mohamed, Amer S, Al-Din
openaire   +2 more sources

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other embryonal tumors

Brain Pathology, EarlyView.
Resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other CNS embryonal tumors are provided. Abstract WHO CNS5 mandates integrated histo‐molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low‐ and lower‐middle‐
Chitra Sarkar, Maysa Al‐Hussaini, Vani Santosh, Vaishali Suri, Sung‐Hye Park, Yue‐Shan Piao, Tarik Tihan, Ho‐Keung Ng, Michael Buckland, Rakesh Jalali, Yonehiro Kanemura, Pieter Wesseling, Takashi Komori   +12 more
wiley   +1 more source

Detection of Cauda Equine Syndrome With ¹⁸F-FDG PET/CT and Leptomeningeal Metastasis by ⁶⁸Ga-DOTATATE in the Same Patient With Large Cell Neuroendocrine Carcinoma of Lung

, 2021
Leptomeningeal metastasis is the metastatic spread of the disease to leptomeninges from solid tumors such as breast, lung cancer, and melanoma. Cauda equine syndrome is a neurological condition caused by compression of the cauda equine.
Erol, Ozge, Sahin, Rahime, cermik, Tevfik Fikret, Arslan, Esra, BEYHAN, EDİZ   +4 more
core   +1 more source

A case of metastatic leptomeningeal carcinomatosis from early gastric carcinoma

World Journal of Surgical Oncology, 2012
Metastatic leptomeningeal carcinomatosis is estimated to occur in 3% to 8% of solid carcinomas. The most common causes of leptomeningeal carcinomatosis are breast cancer, lung cancer and malignant melanoma.
Park Kwang-Kuk, Yang Song-I, Seo Kyung-Won, Kim Young-Ok, Yoon Ki-Young   +4 more
doaj   +1 more source

Glioblastoma, IDH-wildtype with leptomeningeal metastasis to Meckel’s cave: A case report

Acta Radiologica Open, 2022
Meckel’s cave or the trigeminal cistern is a subarachnoid space near the apex of the petrous portion of the temporal bone and contains cerebrospinal fluid and the Gasserian ganglion, which divides into the ophthalmic (V1), maxillary (V2), and mandibular (
Toshiki Murata, Masazumi Matsuda, Tetsugaku Shinozaki, Koichi Ishiyama   +3 more
doaj   +1 more source

Circumscribed Meningeal Melanocytic Neoplasms: CNS WHO Grade, Molecular Profile, and Clinical Outcomes

Brain Pathology, EarlyView.
In this study including 31 circumscribed meningeal melanocytic neoplasms (melanocytoma, intermediate‐grade melanocytic tumor [IMT], and melanoma), overall survival (OS) differed significantly among the groups, with melanoma showing significantly worse OS than melanocytoma and IMT showing intermediate OS between melanocytoma and melanoma.
Yi Zhu, Nishika Karbhari, Timothy J. Kaufmann, Aditya Raghunathan, Cristiane M. Ida, Cinthya J. Zepeda‐Mendoza, Ian J. Dryden, Shahriar Salamat, Chathu Atherton, Sarah M. Jenkins, Svetomir N. Markovic, Ugur T. Sener, Caterina Giannini   +12 more
wiley   +1 more source

Experimental Treatments for Leptomeningeal Metastases from Solid Malignancies

, 2017
Background: Leptomeningeal metastasis is a consequence of advanced solid malignancies and has limited treatment options. It is possible that it is becoming more common as the leptomeninges act as a sanctuary site for recurrence from systemic cancer ...
Keiran S. Smalley, Smalley, Keiran S., Tran, Nam D., Nam D. Tran, Solmaz Sahebjam, Sahebjam, Solmaz, Forsyth, Peter A., Peter A. Forsyth   +7 more
core   +1 more source