Results 71 to 80 of about 274,618 (211)

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Leptomeningeal Metastasis with Perivascular Invasion in a Case of Breast Carcinoma: A Radiological Perspective

Journal of Medical Sciences
Leptomeningeal metastasis (LM) is an under-recognized radiological entity that often mimics classic leptomeningeal disease but presents with perivascular invasion.
Rekha Gupta, Chandrika Sachar, Sanjeev Jindal, Ritika Gupta   +3 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, Volume 38, Issue 61, 2 November 2026.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Efficacy of Osimertinib in EGFR-Mutated Non-Small Cell Lung Cancer with Leptomeningeal Metastases Pretreated with EGFR-Tyrosine Kinase Inhibitors

, 2018
International audienceThe prognosis of patients with non-small cell lung cancer (NSCLC) who develop leptomeningeal metastasis (LM) is ...
Gervais, Radj, Marcq, Marie, Dubos-Arvis, Catherine, Renault, Aldo, Auliac, Jean-Bernard, François, Geraldine, Perol, Maurice, Janicot, Henri, Guisier, Florian, Saboundji, Karima, Odier, Luc, Chouaid, Christos   +11 more
core   +1 more source

Leptomeningeal metastasis from extracranial solid tumors

Cancer Research, Statistics, and Treatment, 2020
Background: Leptomeningeal metastasis (LM) is a dreaded complication associated with solid tumors which is increasing due to the advances in cancer-directed therapy.
Dilip Harindran Vallathol, Vijay Maruti Patil, Vanita Noronha, Amit Joshi, Nandini Menon, Kumar Prabhash   +5 more
doaj   +1 more source

Multicenter Retrospective Study of the Impact of Localized Therapy on Prognosis in Patients With Oligometastatic Solid Tumors

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Background Local therapy has recently been applied to treat oligometastatic cancer across various malignant cancers. However, definitive evidence for local treatment regimens remains lacking. We aimed to evaluate the clinical outcomes of combining local therapy with systemic treatment for patients with oligometastatic solid tumors including ...
Xueman Deng, Duoguang Wu, Luting Ni, Wei Li, Zhijun Liu, Jiewei Liu, Jieqiong Liu   +6 more
wiley   +1 more source

Leptomeningeal dissemination and vertebral bone involvement in a child with pilocytic astrocytoma

, 2016
In low-grade glioma, metastasis is rarely seen. Few cases of leptomeningeal dissemination have been reported in children. Vertebral bone metastasis has not been reported so far.

core   +2 more sources

Leptomeningeal metastasis in breast cancer - a systematic review

Oncotarget, 2015
There is limited data on the impact of specific patient characteristics, tumor subtypes or treatment interventions on survival in breast cancer LM.A systematic review was conducted to assess the impact of hormone receptor and HER-2 status on survival in breast cancer LM.
Scott, Brian J., Oberheim-Bush, Nancy A., Kesari, Santosh   +2 more
openaire   +3 more sources

The microbiome and brain metastasis in non‐small cell lung cancer: A graded appraisal and a framework for prevention‐oriented research

Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.
This Review proposes a microbiome–premetastatic brain niche axis connecting gut, lung, and intratumoral microbes with metabolites, blood–brain barrier remodeling, neuroimmune priming, and brain metastasis in NSCLC. It integrates current evidence while distinguishing established mechanisms from associations and hypotheses requiring prospective and ...
Long Liang, Fangjuan Hu, Xiaofeng Wang, Chunhan Tang, Chun Wang, Gefei Jiang, Chungang Zhao, Yin Zhang, Churong Li   +8 more
wiley   +1 more source

Leptomeningeal dissemination of ovarian carcinoma through a ventriculopenitoneal shunt

, 2008
Background. Dissemination of ovarian cancer occurs mainly within the peritoneal cavity and central nervous system involvement (CNS) is encountered rarely.
Aydin, Zeki, Berkman, Sinan, Topuz, Erkan, Saip, Pinar, Eralp, Yesim   +4 more
core   +1 more source