Results 201 to 210 of about 392,608 (242)

Physician-Assisted Suicide: The Ultimate Freudian Legacy [PDF]

, 2002
Maloof, George
core   +1 more source

Survival Outcomes of Gemcitabine–Cisplatin–S‐1 Versus Gemcitabine–Cisplatin in Unresectable Biliary Tract Cancer: A Multicenter Retrospective Study With a Focus on Conversion Surgery

Annals of Gastroenterological Surgery, EarlyView.
In this multicenter retrospective study conducted by the Biliary Tract Club, we compared survival outcomes between gemcitabine–cisplatin–S‐1 (GCS) and gemcitabine–cisplatin (GC) in patients with unresectable biliary tract cancer, with a particular focus on conversion surgery. GCS was associated with longer overall and progression‐free survival compared
Hisashi Kosaka, Masahiko Kinoshita, Satoshi Yasuda, Satoru Kakizaki, Rie Sugimoto, Jun Sakata, Kiyonori Yamai, Takeshi Hatanaka, Yusuke Yamamoto, Toshifumi Sato, Toru Ishikawa, Takanori Morikawa, Jun Hanaoka, Haruki Mori, Hidenori Toyoda, Tsuyoshi Sanuki, Misaki Yokoi, Hiroyuki Shibata, Koji Fukuda, Kazuhito Kawata, Koji Amaya, Takashi Ito, Masaaki Hidaka, Atsushi Naganuma, Keishi Sugimachi, Satoshi Toshiyama, Makoto Yamasaki, Masaki Kaibori   +27 more
wiley   +1 more source

Eliglustat prevents acute kidney injury caused by Shiga toxin 2 in lethal and sublethal rat models of hemolytic uremic syndrome. [PDF]

Front Pharmacol
Sánchez DS, Fischer Sigel LK, Zotta E, Silberstein C.   +3 more
europepmc   +1 more source

A Defined Patho-Mechanism for Acute Radiation Syndrome Death and a Three-Drug Regimen to Prevent It. [PDF]

Int J Mol Sci
Fahl WE, Goesch HR, Goesch SR, Fahl BL.
europepmc   +1 more source

Establishing the Kenya National Antivenom Quality Control Laboratory: Preclinical Efficacy Results of Four Antivenoms Against Venoms from the "Big Five" Snake Species in Kenya. [PDF]

Toxins (Basel)
Musabyimana V, Kagira JM, Lubuya J, Ngugi CW, Musau BM, Ogopotse W, Maranga G, Kotti D, Khasandi PM, Adino E, Thomas BC, Modahl CM, Mwethera PG, Harrison RA, Casewell NR, Oluoch GO.   +15 more
europepmc   +1 more source

Dose Is a Critical Factor Affecting Treatment Volumes for Integrated Nanosecond Pulse Irreversible Electroporation (INSPIRE). [PDF]

IEEE Trans Biomed Eng
Sano MB, Fong JA, Williamson RH, Darrow J, Reeg L, Mathews KG, Fogle CA, Nelson NC, Iuga AC, Gerber DA.   +9 more
europepmc   +1 more source

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ROBUST ESTIMATION OF THE MEDIAN LETHAL DOSE

Journal of Biopharmaceutical Statistics, 2002
Alternatives to M-estimation for robust estimation of the median lethal dose in biological assays are developed. A class of link functions based on the Student-t distribution is proposed, where degrees of freedom are estimated from the data by maximum likelihood. Other alternatives include slash and finite mixture distributions.
G E, Kelly, J K, Lindsey
openaire   +2 more sources

Lethality in the Rat as a Function of Dose Pattern

The British Journal of Radiology, 1958
Rats exposed seven days to a chronic field of 2 r/hour of 60Co γ rays immediately prior to or immediately after an acute dose of 800 r of 60Co γ rays did not exhibit a significant difference in either a 30-day or 90-day mortality. When compared to a group of rats receiving only an acute dose of 800 r of 60Co γ rays, both acute-chronic groups evidenced ...
Q L, HARTWIG, G S, MELVILLE, T P, LEFFINGWELL   +2 more
openaire   +2 more sources

A Lethal Dose of RNA

Science, 2013
A new generation of genetically modified crops will kill insects by silencing their genes.
openaire   +1 more source

Interval Estimation of the Median Lethal Dose

Biometrics, 1986
Assuming a logistic dose-response curve, one can construct a confidence interval for the LD50 from the asymptotic likelihood ratio test. Reasons are given for preferring this likelihood ratio interval to the established interval calculated by applying Fieller's theorem to the maximum likelihood estimates.
openaire   +3 more sources