Results 81 to 90 of about 234,415 (300)

A new mathematical model for radiation cell killing mechanism: Target cumulating model

, 2009
There are numerous mathematical or statistical models have been given out for radiation cell killing mechanism. Unfortunately, none of the model could explain the mechanism perfectly.
Xie Congyin, Zhang Li, Zhao Liang, Wu Shixiu   +3 more
core  

The influence of late-stage pupal irradiation and increased irradiated:un-irradiated male ratio on mating competitiveness of the malaria mosquito Anopheles arabiensis Patton

, 2009
Competitiveness of released males in genetic control programmes is of critical importance. In this paper, we explored two scenarios to compensate for the loss of mating competitiveness after pupal stage irradiation in males of the malaria mosquito ...
Knols, B.G.J., Helinski, M.
core   +1 more source

Dose letal de radiação gama para ovos de Corcyra cephalonica (Stainton, 1865) (Lepidoptera: Pyralidae), traça do arroz Lethal dose of gamma radiation for eggs of Corcyra cephalonica (Stainton, 1865) (Lepidoptera: Pyralidae), rice moth

Scientia Agricola, 1994
O. experimento teve como objetivo observar os efeitos da radiação gama em ovos da traça do arroz, Corcyra cephalonica (STAINTON, 1865). As doses utilizadas no experimento foram; 0; 25; 50; 75; 100; 125; 150; 175; 200 Gy.
J.A. Duarte Aguilar, V. Arthur
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Increased Radioresistance to Lethal Doses of Gamma Rays in Mice and Rats after Exposure to Microwave Radiation Emitted by a GSM Mobile Phone Simulator

, 2013
The aim of this study was to investigate the effect of pre-irradiation with microwaves on the induction of radioadaptive response. In the 1 st phase of the study, 110 male mice were divided into 8 groups.
S Bonyadi, M Haghani, M Shafie, A Jamali, SMJ Mortazavi, M Taheri, AR Tavassoli, R Ghalandari, AR Mehdizadeh, MA Mosleh-Shirazi, SAS Namazi   +10 more
core   +1 more source

Acute toxicity and anthelmintic efficacy of khimedol

Российский паразитологический журнал, 2019
The purpose of the research: to study acute toxicity and anthelmintic efficacy of khimedol, a new anthelmintic preparation. Materials and methods. Khimedol, anthelmintic preparation which was received by means of streamlined synthesis in the Institute ...
K. R. Toimbetova, M. A. Arzybaev, A. B. Shakirov, A. M. Malabaeva, N. . Shyityeva   +4 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The murine intravenous median lethal dose (LD₅₀) of the haemotoxic snake venoms used in this study.

, 2021
The murine intravenous median lethal dose (LD50) of the haemotoxic snake venoms used in this study.
Robert A. Harrison (7062377), Nessrin Alomran (11292837), Jaffer Alsolaiss (4520917), Nicholas R. Casewell (7062380), Edouard Crittenden (11292840), Stuart Ainsworth (4520902), Laura-Oana Albulescu (175562)   +6 more
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source