Results 261 to 270 of about 988,812 (316)

A Synergistic Dual-Antibody Cocktail Targeting α-Toxin Protects Against Invasive <i>Staphylococcus aureus</i> Infection by Neutralizing Virulence and Enhancing Host Defense. [PDF]

MedComm (2020)
Zhao L, Song Z, Fan H, Wang L, Yang Y, Jing H, Xia X, Wang Y, Feng L, Wang S, Chen Z, Gou Q, Yuan Y, Zhang J, Zou Q, Zeng H.   +15 more
europepmc   +1 more source

A scoping review of adverse events associated with concomitant beta‐adrenoreceptor blockers and selective serotonin reuptake inhibitors

British Journal of Clinical Pharmacology, EarlyView.
Beta‐adrenoreceptor blockers (beta‐blockers) and selective serotonin reuptake inhibitors (SSRIs) are commonly used medications and often used together, such as for the treatment of anxiety. However, there is no recent review of any potential adverse events related to concomitant use of medicines from each group.
Ziyi Cai, James Sutton, Charlotte Archer, Caroline S. Copeland, Joseph Hayes, Charles E. Leonard, Nicky Lidbetter, Kenneth K. C. Man, Faraz Mughal, Ian C. K. Wong, Hayley C. Gorton   +10 more
wiley   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Applications of transposon-insertion sequencing for understanding bacterial physiology. [PDF]

Microb Genom
Goodall ECA, van Houte S.
europepmc   +1 more source

Acute Toxicity and No Observable Adverse Effect Level of Nodularin-R in Mice. [PDF]

Toxins (Basel)
Finch SC, Waugh C, Harwood DT, Turnbull AR, Selwood AI, Passfield EMF, Puddick J.   +6 more
europepmc   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Glycosylated dendrimer nanoamplifiers hijack DNA damage‐immune crosstalk for enhanced dual‐track therapy of orthotopic glioblastoma

BMEMat, EarlyView.
A glycosylated dendrimer nanoamplifier hijacks DNA damage‐immune crosstalk for enhanced radio‐immunotherapy of glioblastoma. The responsive release of demethylcantharidin simultaneously blocks repair‐mediated resistance by inhibiting DNA repair and overcomes adaptive immune resistance.
Cong Song, Binghan Liu, Junjie Liu, Ce Li, Wenqing Man, Xurui Sun, Chang Yuan, Yanjun Wang, Hong Pan, Shuanglian Wang, Zhiming Zheng   +10 more
wiley   +1 more source

Glycopolymeric nanoparticles transported by activated platelets protect ischemic myocardium by alleviating PANoptosis through targeting macrophage Dectin‐1

BMEMat, EarlyView.
NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu, Na Yang, Yan Zhang, Lingxin Peng, Yi Li, Yue Chao, Qinfang Miao, Haikun Qi, Jianhui Zhuang, Weixia Jian, Bingyu Li, Wenhui Peng, Jinghua Chen, Shiyu Gong   +13 more
wiley   +1 more source

Isolation, Genomic Evolution, and Pathogenicity of <i>Clostridium perfringens</i> Type A Causing Hemorrhagic Enteritis in Adult Yaks in Southwest China. [PDF]

Animals (Basel)
Zhao L, Miao Y, Yang Z, Shen K, Xu D, Zhang S, Yang L, Fu L, Li Z, Lian B, Yu Y.   +10 more
europepmc   +1 more source

Isolation of Monoclonal Neutralizing Single-Domain Antibodies Against Clostridioides difficile Toxin B. [PDF]

Acta Naturae
Alekseeva IA, Ungur AS, Favorskaya IA, Tukhvatulin AI, Shcheblyakov DV, Korobkova AI, Komyakova ME, Voronina OL, Ryzhova NN, Ermolova EI, Kunda MS, Logunov DY, Bobrova MM, Makarov VV, Yudin SM, Gintsburg AL.   +15 more
europepmc   +1 more source