Results 281 to 290 of about 120,091 (334)

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Destabilization of IL-8 mRNA by Anthrax Lethal Toxin: Demonstration of the Requirement for TTP and Examination of its Cellular Interactions

, 2012
Man Chi Edith Chow
openalex   +1 more source

Learning to explain environmental crises: A dialogic analysis of teacher professional learning between Chile and the United States

British Educational Research Journal, EarlyView.
Abstract Many studies and initiatives are animated by the potential for science education to intervene in the climate crisis and crises of environmental degradation and disinformation. For science teachers to learn to address these issues in their classes, their teaching must expand beyond scientific facts and face controversial social aspects. Dealing
Valeria M. Cabello, Alejandra Frausto Aceves, Daniel Morales‐Doyle   +2 more
wiley   +1 more source

Comparative Analysis of Insect Resistance in Transgenic <i>Populus × euramericana</i> cv. Neva Expressing Dual <i>Bt</i> Genes from Different Sources. [PDF]

Plants (Basel)
Li J, Zhang J, Li H, Wang C, Yan X, Ren Y, Wang J, Yang M.   +7 more
europepmc   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Exposure Type and Duration Determine Ecotoxicological Effects of Cyanobacteria Anatoxins on the Benthic Amphipod <i>Hyalella azteca</i>. [PDF]

Toxins (Basel)
Yogeshwar IK, Kalis EJJ, Geist J, Beggel S.   +3 more
europepmc   +1 more source

Micro/nanorobots for detecting and eliminating biological and chemical warfare agents

BMEMat, EarlyView.
Fuel‐powered and field‐driven micro/nanorobots provide a cutting‐edge platform to safeguard national security and defense. This review reports the latest research progress in micro/nanorobots in sensing and detoxifying biological and chemical warfare agents.
Song Li, Huaijuan Zhou, Di Shi, Zdeněk Sofer, Jinhua Li   +4 more
wiley   +1 more source

A targeted antiferromagnetic nanoprobe for ultra‐sensitive magnetic resonance imaging detection of sub‐millimeter esophageal tumors

BMEMat, EarlyView.
We developed a cyclo‐RGD peptide‐conjugated antiferromagnetic nanoparticle (RANP) as a targeted T1 contrast agent. Under 9 T MRI conditions, RANP exhibited an r1 value of 1.88 mM−1 s−1 and a low r2/r1 ratio of 1.84, enabling the detection of esophageal tumors as small as 0.8 mm in vivo. Abstract Early, non‐invasive detection of esophageal cancer at sub‐
Wenkui Mo, Zeyu Liang, Bo Zhang, Lin Xiao, Xun Liu, Zhigao Yi, Shangzhi Xie, Qiyue Wang, Liang Shi, Taobo Luo, Feng Li, Leilei Wu, Yuanzhe Piao, Fangyuan Li, Jian Zeng, Daishun Ling   +15 more
wiley   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

[Thermolabile lethal toxin of pathogenic staphylococci].

Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1972
openaire   +1 more source