Results 1 to 10 of about 549,884 (335)

Enhancing Muscle Quality: Exploring Leucine and Whey Protein in Sarcopenic Individuals. [PDF]

J Cachexia Sarcopenia Muscle
Ijaz A, Ain HBU, Tufail T, Mariam R, Noreen S, Amjad A, Ikram A, Arshad MT, Abdullahi MA.   +8 more
europepmc   +3 more sources

The association between dietary branched-chain amino acids and the risk of cardiovascular diseases in Chinese patients with type 2 diabetes: A hospital-based case–control study

Frontiers in Nutrition, 2022
BackgroundPrevious studies showed conflicting evidence on the association between the intake of dietary branched-chain amino acid (BCAA) and the risk of cardiovascular disease (CVD). However, this relationship has not been studied in patients with type 2
Lu Zheng, Jun Cai, Yong-hui Feng, Xin Su, Shi-yun Chen, Jia-zi Liu, Wan-lin Li, Rui-qing Ouyang, Jun-rong Ma, Chen Cheng, Ying-jun Mu, Shi-wen Zhang, Kai-yin He, Fang-fang Zeng, Yan-bin Ye, Yan-bin Ye   +15 more
doaj   +1 more source

Different Effects of Leucine Supplementation and/or Exercise on Systemic Insulin Sensitivity in Mice

Frontiers in Endocrinology, 2021
ObjectiveObesity-related diseases such as diabetes, hypertension, dyslipidemia, and cardiovascular diseases have increased due to the obesity epidemic. Early intervention for obesity through lifestyle and nutrition plays an important role in preventing ...
Xiaofan Jiang, Yuwei Zhang, Weichao Hu, Yuxiu Liang, Liang Zheng, Juan Zheng, Juan Zheng, Baozhen Wang, Xin Guo   +8 more
doaj   +1 more source

Leucine Reduced Blood–Brain Barrier Disruption and Infarct Size in Early Cerebral Ischemia-Reperfusion

Brain Sciences, 2023
A disruption of the blood–brain barrier (BBB) is a crucial pathophysiological change that can impact the outcome of a stroke. Ribosomal protein S6 (S6) and protein kinase B (Akt) play significant roles in early cerebral ischemia-reperfusion injury ...
Oak Z. Chi, Xia Liu, Jedrick Magsino, Harvey R. Weiss   +3 more
doaj   +1 more source

Vcp Overexpression and Leucine Supplementation Increase Protein Synthesis and Improve Fear Memory and Social Interaction of Nf1 Mutant Mice

Cell Reports, 2020
Summary: Neurofibromatosis type 1 (NF1) is a dominant genetic disorder manifesting, in part, as cognitive defects. Previous study indicated that neurofibromin (NF1 protein) interacts with valosin-containing protein (VCP)/P97 to control dendritic spine ...
Yu-Tzu Shih, Tzyy-Nan Huang, Hsiao-Tang Hu, Tzu-Li Yen, Yi-Ping Hsueh   +4 more
doaj   +1 more source

Effects of dietary leucine on growth, antioxidant capacity, immune response, and inflammation in juvenile yellow catfish Pelteobagrus fulvidraco

Frontiers in Physiology, 2023
The experiment was conducted to investigate the effects of dietary leucine on growth, antioxidant capacity, immune response, and inflammation in juvenile yellow catfish.
Dexiang Feng, Yangping Yu, Kaifang Liu, Yi Su, Tianyu Fan, Xusheng Guo, Ming Li   +6 more
doaj   +1 more source

Amino Acid Carriers of the Solute Carrier Families 7 (SLC7) and 38 (SLC38) Are Involved in Leucine Sensing in the Brain of Atlantic Salmon (Salmo salar)

Frontiers in Marine Science, 2021
Sensing of amino acids in fish brain, especially branched-chain amino acids (BCAA) like leucine, is involved in regulation of feed intake through different mechanisms. However, there is limited information regarding the possible involvement of mechanisms
Sara Comesaña, Floriana Lai, Ann-Elise Olderbakk Jordal, Tiziano Verri, Marit Espe, José L. Soengas, Ivar Rønnestad   +6 more
doaj   +1 more source

Leucine Contributes to Copper Stress Tolerance in Peach (Prunus persica) Seedlings by Enhancing Photosynthesis and the Antioxidant Defense System

Antioxidants, 2022
Heavy metal contamination has a severe impact on ecological health and plant growth and is becoming increasingly serious globally. Copper (Cu) is a heavy metal that is essential for the growth and development of plants, including peach (Prunus persica L.
Maoxiang Sun, Suhong Li, Qingtao Gong, Yuansong Xiao, Futian Peng   +4 more
doaj   +1 more source

The Effect of Ex Vivo Human Serum from Liver Disease Patients on Cellular Protein Synthesis and Growth

Cells, 2022
Sarcopenia is a common complication affecting liver disease patients, yet the underlying mechanisms remain unclear. We aimed to elucidate the cellular mechanisms that drive sarcopenia progression using an in vitro model of liver disease.
Sophie L. Allen, Alex P. Seabright, Jonathan I. Quinlan, Amritpal Dhaliwal, Felicity R. Williams, Nicholas H. F. Fine, David J. Hodson, Matthew J. Armstrong, Ahmed M. Elsharkaway, Carolyn A. Greig, Yu-Chiang Lai, Janet M. Lord, Gareth G. Lavery, Leigh Breen   +13 more
doaj   +1 more source

Microbiota based personalized nutrition improves hyperglycaemia and hypertension parameters and reduces inflammation: a prospective, open label, controlled, randomized, comparative, proof of concept study [PDF]

PeerJ
Background Recent studies suggest that gut microbiota composition, abundance and diversity can influence many chronic diseases such as type 2 diabetes.
Gopalakrishna Kallapura, Anthony Surya Prakash, Kumar Sankaran, Prabhath Manjappa, Prayagraj Chaudhary, Sanjay Ambhore, Debojyoti Dhar   +6 more
doaj   +2 more sources