Results 31 to 40 of about 285,613 (247)

Advanced Oral Delivery Systems for Nutraceuticals

Advanced Healthcare Materials, EarlyView.
Emerging delivery technologies are explored to overcome barriers to oral nutraceutical absorption. Traditional carriers are compared with novel platforms including biodegradable polymers, MOFs, MPNs, and 3D printing. These systems enhance bioavailability, control release, and enable personalized nutrition.
Xin Yang, Linzixuan Zhang, Zhiling Zheng, Robert Langer, Ana Jaklenec   +4 more
wiley   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

A Multifunctional Binder for Current‐Collector‐Free Zn Powder Anodes

Advanced Materials, EarlyView.
By introducing abundant polar groups as Zn2+ absorption sites and hydrogen bond arrays, a protein structure‐derived binder for ZP anode and iodine cathode is proposed. This design can regulate the Zn2+ flux, benefit the formation of free‐standing electrode, inhibit the side reactions, suppress the shuttle effect of polyiodides, and enable the large ...
Yanbo Wang, Xintao Ma, Xinru Yang, Rong Zhang, Hu Hong, Shixun Wang, Qing Li, Ze Chen, Zhaodong Huang, Haiming Lv, Chunyi Zhi   +10 more
wiley   +1 more source

Mussel‐Inspired Molecular Strategies for Fabricating Functional Materials With Underwater Adhesion and Self‐Healing Properties

Advanced Materials, EarlyView.
This review systematically examines the nanomechanical mechanisms of mussel‐inspired molecular interactions, primarily investigated by direct force measurement techniques such as surface forces apparatus and atomic force microscopy. The macroscopic adhesive and self‐healing performances of mussel‐inspired functional materials, including coacervates ...
Pan Huang, Hongjian Zhang, Hongbo Zeng
wiley   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Ion Valency as a Molecular Switch for Salt‐Resistant Underwater Adhesion

Advanced Materials, EarlyView.
Monovalent K+ ions weaken adhesion by forming K+‐π complexes with weak bridging capacity. In contrast, multivalent cations like Y3+ enhance adhesion by forming stable π‐cation‐π bridging networks, which are resistant to salt and capable of compensating for the loss of native π–π and NH3+‐π interactions.
Chang‐Sheng Wang, Jiaxing Zhang, Hu Zhang, Wojciech Raj, Nahid Hassanpour, Duy Anh Pham, Hui Guo, Xingxun Liu, Heng Chang, Alexandre A. Arnold, Isabelle Marcotte, Rongxin Su, Wei Qi, Xavier Banquy   +13 more
wiley   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Asymmetric Strategies for the Synthesis of Enantiopure α‐/β‐/γ‐Thio‐Carboxylic Acids Bearing a Stereocentre at CS Bond

Advanced Synthesis &Catalysis, EarlyView.
Enantioenriched α‐/β‐/γ‐thiocarboxylic acids featuring C–S chirality are valuable targets in organic synthesis. This review outlines recent progress in their asymmetric synthesis, including chiral pool approaches, metal‐ /organo‐catalysis, and emerging biocatalytic strategies. Enantiomerically pure α‐/β‐/γ‐thiocarboxylic acids bearing a stereocentre at
Jingyue Wu, Daniele Castagnolo
wiley   +1 more source