Results 51 to 60 of about 370,537 (284)

Administration of valine, leucine, and isoleucine improved plasma cholesterol and mitigated the preatherosclerotic lesions in rats fed with hypercholesterolemic diet

Romanian Journal of Laboratory Medicine, 2018
Hypercholesterolemia has a major contribution to the occurrence and progression of atherosclerotic lesions. Recent studies report the involvement of branched-chain amino acids in cholesterol methabolism.
Ifrim Simona, Amalinei Cornelia, Cojocaru Elena, Matei Mioara Calipsoana   +3 more
doaj   +1 more source

Glucose-dependent control of leucine metabolism by leucyl-tRNA synthetase 1

Science, 2019
A tRNA synthase in metabolic control Leucyl-tRNA synthetase 1 (LARS1), which covalently couples leucine to its cognate transfer RNAs (tRNAs), appears to have broader roles in the control of leucine metabolism.
Ina Yoon, M. Nam, Hoi Kyoung Kim, H. Moon, Sungmin Kim, Jayun Jang, Ji Ae Song, Seung Jae Jeong, Sang Bum Kim, Seongmin Cho, Younha Kim, Jihye Lee, Won Suk Yang, H. Yoo, Kibum Kim, Min-Sun Kim, Aerin Yang, Kyukwang Cho, Hee-Sung Park, G. Hwang, K. Hwang, J. Han, J. H. Kim, Sunghoon Kim   +23 more
semanticscholar   +1 more source

Synthesis and spectroscopic studies of new leucine acid derivative with their metal complexes. [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2013
A new ligand N-[(acetyl amino)-thioxo methyl]leucine(ATL) are synthesized by reaction of acetyl-isothio cyanate with leucine acid. The ligand is characterized by elemental analysis, FT-IR and NMR spectra, some transition metal complex of this ligand were
Muhammed Ahmed.Awaad, Basima M.Sarhan, Abdul Sattar Z.Khalaf   +2 more
doaj   +1 more source

Leucine, Not Total Protein, Content of a Supplement Is the Primary Determinant of Muscle Protein Anabolic Responses in Healthy Older Women.

Journal of NutriLife, 2018
Background Older adults show a blunted muscle protein synthesis (MPS) response to postprandial hyperaminoacidemia relative to younger adults. Evidence suggests that this anabolic resistance can be overcome by consuming greater quantities of leucine ...
M. Devries, C. McGlory, D. Bolster, Alison G Kamil, Maike Rahn, L. Harkness, S. Baker, Stuart M Phillips   +7 more
semanticscholar   +1 more source

Leucine in the Sky with Diamonds [PDF]

Structure, 2003
AbstractNew structures of LD motifs bound to the focal adhesion targeting domain show that the motifs are recognized as amphipathic α helices. The structures highlight the structural and functional diversity of leucine and aspartic acid-based targeting motifs.
openaire   +2 more sources

Evidence for a Role for Sestrin1 in Mediating Leucine‐Induced Activation of mTORC1 in Skeletal Muscle

American Journal of Physiology. Endocrinology and Metabolism, 2019
Previous studies established that leucine stimulates protein synthesis in skeletal muscle to the same extent as a complete mixture of amino acids, and the effect occurs through activation of the mechanistic target of rapamycin in complex 1 (mTORC1 ...
Dandan Xu, K. Shimkus, H. Lacko, Lydia Kutzler, L. Jefferson, S. Kimball   +5 more
semanticscholar   +1 more source

Perfect state transfers by selective quantum interferences within complex spin networks [PDF]

Phys. Rev. A 81, 060302(R) (2010), 2010
We present a method that implement directional, perfect state transfers within a branched spin network by exploiting quantum interferences in the time-domain. That provides a tool to isolate subsystems from a large and complex one. Directionality is achieved by interrupting the spin-spin coupled evolution with periods of free Zeeman evolutions, whose ...
arxiv   +1 more source

Protein leucine content is a determinant of shorter- and longer-term muscle protein synthetic responses at rest and following resistance exercise in healthy older women: a randomized, controlled trial.

American Journal of Clinical Nutrition, 2018
Background Older women may not be consuming enough protein to maintain muscle mass. Augmentation of protein intake with leucine may enhance the muscle protein synthetic response in older women to aid in maintaining muscle mass.
M. Devries, C. McGlory, D. Bolster, Alison G Kamil, Maike Rahn, L. Harkness, S. Baker, Stuart M Phillips   +7 more
semanticscholar   +1 more source

The association between dietary branched-chain amino acids and the risk of cardiovascular diseases in Chinese patients with type 2 diabetes: A hospital-based case–control study

Frontiers in Nutrition, 2022
BackgroundPrevious studies showed conflicting evidence on the association between the intake of dietary branched-chain amino acid (BCAA) and the risk of cardiovascular disease (CVD). However, this relationship has not been studied in patients with type 2
Lu Zheng, Jun Cai, Yong-hui Feng, Xin Su, Shi-yun Chen, Jia-zi Liu, Wan-lin Li, Rui-qing Ouyang, Jun-rong Ma, Chen Cheng, Ying-jun Mu, Shi-wen Zhang, Kai-yin He, Fang-fang Zeng, Yan-bin Ye, Yan-bin Ye   +15 more
doaj   +1 more source

Leucine partially protects muscle mass and function during bed rest in middle-aged adults.

American Journal of Clinical Nutrition, 2016
BACKGROUND Physical inactivity triggers a rapid loss of muscle mass and function in older adults. Middle-aged adults show few phenotypic signs of aging yet may be more susceptible to inactivity than younger adults.
K. English, Joni A. Mettler, J. Ellison, M. M. Mamerow, Emily J. Arentson-Lantz, James M. Pattarini, R. Ploutz-Snyder, M. Sheffield-Moore, D. Paddon-Jones   +8 more
semanticscholar   +1 more source