Results 91 to 100 of about 40,253 (233)

Top 5 Advances in the Last 50 Years: Malignant Gastric and Esophageal Surgery

World Journal of Surgery, EarlyView.
Luís Santos Castro, Lorenzo Ferri
wiley   +1 more source

Predicting Prognosis for Gastric Cancer Patients Receiving Neoadjuvant Treatment With Body Composition‐Based Deep Learning

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background This study sought to develop an innovative body composition (BC)‐based deep learning (DL) model to precisely evaluate survival in gastric cancer (GC) patients undergoing neoadjuvant treatment (NT). Materials and Methods This retrospective study included GC patients undergoing NT from two centers.
Yingjing Zhang, Tong Tong, Bowen Hou, Tian Yu, Pengfei Su, Jianchun Yu, Yakai Huang   +6 more
wiley   +1 more source

Schedule-selective biochemical modulation of 5-fluorouracil in advanced colorectal cancer – a phase II study

BMC Cancer, 2002
Background 5-fluorouracil remains the standard therapy for patients with advanced/metastatic colorectal cancer. Pre-clinical studies have demonstrated the biological modulation of 5-fluorouracil by methotrexate and leucovorin.
Savage Paul, White Douglas R, Higgs Vetta, Melin Susan A, Tomlinson Shannon K, Case Douglas, Blackstock A William   +6 more
doaj   +1 more source

Primary tumor sidedness and benefit from FOLFOXIRI plus bevacizumab as initial therapy for metastatic colorectal cancer. Retrospective analysis of the TRIBE trial by GONO [PDF]

, 2018
Right-sided metastatic colorectal cancer (mCRC) patients have poor prognosis and achieve limited benefit from first-line doublets plus a targeted agent.
Allegrini, G, Antoniotti, C, Bergamo, F, Boni, L, Buonadonna, A, Cortesi, E, Cremolini, C, Falcone, A, Fontanini, G, Granetto, C, Lonardi, S, Loupakis, F, Marmorino, F, Masi, G, Moretto, R, Racca, P, Ronzoni, M, Sensi, E, Tomasello, G, Tonini, G, Zagonel, V, Zaniboni, A   +21 more
core   +3 more sources

Pancreatic Cancer—Advances in the Last 50 Years

World Journal of Surgery, EarlyView.
S. George Barreto, Anirban Maitra, Eileen M. O'Reilly, Dushyant Sahani, Richard Zheng, Charles J. Yeo   +5 more
wiley   +1 more source

Efficacy of Hepatic Artery Infusion Chemotherapy Combined With Regorafenib and Sintilimab Versus Regorafenib Alone in MSS/pMMR Colorectal Cancer Liver Metastases After Second‐Line Treatment Failure

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Microsatellite stable/proficient mismatch repair (MSS/pMMR) colorectal cancer liver metastases (CRCLM) have limited treatment options after failure of second‐line systemic therapies. Hepatic artery infusion chemotherapy (HAIC) combined with targeted therapy and immunotherapy may offer improved outcomes.
Ran You, Qingyu Xu, Lixing Wang, Bin Leng, Chendong Wang, Zeyu Yu, Ya Lu, Lingfeng Diao, Yi Lu, Guowen Yin   +9 more
wiley   +1 more source

A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis

Radiation Oncology, 2017
Background This study aimed to evaluate the efficacy of a high dose of oral tegafur-uracil (400 mg/m2) plus leucovorin with preoperative chemoradiation of locally advanced rectal cancer and to explore the impact of polymorphisms of cytochrome P 2A6 ...
Sun Young Kim, Ji Yeon Baek, Jae Hwan Oh, Sung Chan Park, Dae Kyung Sohn, Min Ju Kim, Hee Jin Chang, Sun-Young Kong, Dae Yong Kim   +8 more
doaj   +1 more source

Epidemiology and natural history of central venous access device use and infusion pump function in the NO16966 trial [PDF]

, 2014
Background: Central venous access devices in fluoropyrimidine therapy are associated with complications; however, reliable data are lacking regarding their natural history, associated complications and infusion pump performance in patients with ...
A Surov, AA Martoni, C Araújo, C Twelves, D Fagnani, D Haller, DC McGee, DZ Xiang, E Chu, E Chu, E McKenna, E Van Cutsem, EA Poplin, EB Lamont, F Ng, G Perrocheau, H-J Schmoll, I Kriegel, J Cassidy, J Cassidy, J Kawamura, J Shen-Gunther, L Cavanna, L Garrison, LB Saltz, M Gann Jr, M Karthaus, M Verso, M W Saif, MM Beckers, N Barbetakis, N Starling, P Debourdeau, R Biffi, S Lee, T Cartwright, T Conroy, The Meta-Analysis Group In Cancer, W Saber, W Scheithauer, W Sun, Y Inaba   +41 more
core   +2 more sources

Metastasis of Hepatocellular Carcinoma to the Urinary Bladder: A Case Report and Literature Review

IJU Case Reports, Volume 9, Issue 3, May 2026.
ABSTRACT Introduction Although secondary bladder tumors from distant metastases are rare, those originating from hepatocellular carcinoma are particularly uncommon, with only a few cases reported to date. Case Presentation An 81 year old male with hepatocellular carcinoma developed a rapidly growing 23 mm‐sized bladder tumor during systemic therapy ...
Eri Fukagawa, Suguru Oka, Kazushige Sakaguchi, Shigeki Yamamoto, Masako Ikemura, Norio Akuta, Shinji Urakami   +6 more
wiley   +1 more source

Germline and Somatic DNA Damage Repair Gene Mutations and Overall Survival in Metastatic Pancreatic Adenocarcinoma Patients Treated with FOLFIRINOX [PDF]

, 2018
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer with lack of predictive biomarkers. We conducted a study to assess DNA damage repair (DDR) gene mutations as a predictive biomarker in PDAC patients treated with FOLFIRINOX ...
Gbolahan, Olumide, Hancock, Brad A., O'Neil, Bert H., Radovich, Milan, Sehdev, Amikar, Shahda, Safi, Stanley, Melissa, Wan, Jun, Wu, Howard H.   +8 more
core   +1 more source