Results 111 to 120 of about 40,253 (233)

The Value of Caspase-3 after the Application of Annona muricata Leaf Extract in COLO-205 Colorectal Cancer Cell Line

Gastroenterology Research and Practice, 2017
Annona muricata, commonly known as soursop, contains annonacin, acetogenin, and polyphenol which are known to have chemopreventive effects on cancer.
Murdani Abdullah, Ari Fahrial Syam, Sofy Meilany, Bayu Laksono, Oryza Gryagus Prabu, Heri Setiyo Bekti, Lili Indrawati, Dadang Makmun   +7 more
doaj   +1 more source

The role of l-leucovorin uptake and metabolism in the modulation of 5-fluorouracil efficacy and antifolate toxicity

Frontiers in Pharmacology
BackgroundL-Leucovorin (l-LV; 5-formyltetrahydrofolate, folinic acid) is a precursor for 5,10-methylenetetrahydrofolate (5,10-CH2-THF), which is important for the potentiation of the antitumor activity of 5-fluorouracil (5FU).
Godefridus J. Peters, Godefridus J. Peters, Ietje Kathmann, Elisa Giovannetti, Elisa Giovannetti, Kees Smid, Yehuda G. Assaraf, Gerrit Jansen   +7 more
doaj   +1 more source

Chronotherapy with 5-Fluorouracil and Folinic Acid in Advanced Colorectal Carcinoma [PDF]

, 1994
Adler, S., Eibl-Eibesfeldt, B., Emmerich, B., Hallek, M., Lang, S., Langenmayer, Irmgard, Rump, W.   +6 more
core   +1 more source

Efficacy and Safety of Hepatic Artery Infusion Chemotherapy Combined with Donafenib and Camrelizumab in the Treatment of Patients with Unresectable Hepatocellular Carcinoma: A Retrospective, Single-Arm Study

Journal of Hepatocellular Carcinoma
Chenrui Wu,1,* Zixuan Fu,1,* Long Pan,1 Jiachu Li,2 Yin Zhou,3 Ruirui Sun,1 Yang Gou,1 Yaowu Zhao,1 Zhouyan Wang,1 Yuhao Qiu,1 Ping Huang1 1Department of Hepatobiliary Surgery, First Affiliated Hospital of Chongqing Medical University ...
Wu C, Fu Z, Pan L, Li J, Zhou Y, Sun R, Gou Y, Zhao Y, Wang Z, Qiu Y, Huang P   +10 more
doaj  

Pharmacogenomic screening identifies and repurposes leucovorin and dyclonine as pro-oligodendrogenic compounds in brain repair

Nature Communications
Oligodendrocytes are critical for CNS myelin formation and are involved in preterm-birth brain injury (PBI) and multiple sclerosis (MS), both of which lack effective treatments.
Jean-Baptiste Huré, Louis Foucault, Litsa Maria Ghayad, Corentine Marie, Nicolas Vachoud, Lucas Baudouin, Rihab Azmani, Natalija Ivljanin, Alvaro Arevalo-Nuevo, Morgane Pigache, Lamia Bouslama-Oueghlani, Julie-Anne Chemelle, Marie-Aimée Dronne, Raphaël Terreux, Bassem Hassan, François Gueyffier, Olivier Raineteau, Carlos Parras   +17 more
doaj   +1 more source

Leucovorin [PDF]

, 2020
openaire   +1 more source

Mature Results of a Prospective Randomized Trial Comparing 5-Flourouracil with Leucovorin to 5-Flourouracil with Levamisole as Adjuvant Therapy of Stage II and III Colorectal Cancer- The Israel Cooperative Oncology Group (ICOG) Study

Journal of Cancer, 2011
Objective: Survival benefit with adjuvant therapy was shown in patients with Stage III colorectal cancer (CRC). This study evaluates long-term (10-year) outcome in patients with CRC randomly assigned to adjuvant 5-Fluorouracil/Leucovorin (5FU+LV) or 5-FU/
Arie Figer, Aviram Nissan, Adi Shani, Riva Borovick, Mariana Stiener, Mario Baras, Herbert R. Freund, Aaron Sulkes, Alexander Stojadinovic, Tamar Peretz
doaj  

A European consensus recommendation on the management of delayed methotrexate elimination: supportive measures, leucovorin rescue and glucarpidase treatment

Journal of Cancer Research and Clinical Oncology
High-dose methotrexate (HDMTX) is used in the treatment of a range of adult and childhood cancers. Although HDMTX can provide effective anti-tumor activity with an acceptable safety profile for most patients, delayed methotrexate elimination (DME ...
Stefan S. Bielack, Carole Soussain, Christopher P. Fox, Caroline Houillier, Thais Murciano, Wendy Osborne, Pier Luigi Zinzani, Carmelo Rizzari, Stefan Schwartz   +8 more
doaj   +1 more source

Granulocyte colony-stimulating factors for prevention of febrile neutropenia following chemotherapy: systematic review and meta-analysis [PDF]

Background: Febrile neutropenia (FN) occurs following myelosuppressive chemotherapy and is associated with morbidity, mortality, costs, and chemotherapy reductions and delays.
Akehurst, R., Cooper, K.L., Madan, J., Stevenson, M.D., Whyte, S.   +4 more
core  

An Examination of Changes in Urinary Metabolites and Behaviors with the Use of Leucovorin Calcium in Children with Autism Spectrum Disorder (ASD) [PDF]

, 2020
Bent, Stephen, Chen, Yingtong, Hendren, Robert L, McDonald, Michael G, Wahlberg, Jessica, Widjaja, Felicia   +5 more
core