Results 11 to 20 of about 1,755 (134)

Revised safety evaluation of the food enzyme leucyl aminopeptidase from the non‐genetically modified Aspergillus sp. strain AE‐MB [PDF]

EFSA Journal
The food enzyme leucyl aminopeptidase (EC 3.4.11.1) is produced with the non‐genetically modified Aspergillus sp. strain AE‐MB by Amano Enzyme Inc. In a previous evaluation, the Panel concluded that the food enzyme could not be considered safe when used ...
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Monika Sramkova, Henk Van Loveren, Laurence Vernis, Eleonora Marini, Yi Liu   +15 more
doaj   +3 more sources

Expansion and functional diversification of a leucyl aminopeptidase family that encodes the major protein constituents of Drosophila sperm [PDF]

BMC Genomics, 2011
Background The evolutionary diversification of gene families through gene creation (and loss) is a dynamic process believed to be critical to the evolution of functional novelty.
Karr Timothy L, Wilkin Elaine C, Dorus Steve   +2 more
doaj   +2 more sources

Leucyl and Cystinyl Aminopeptidase as a Prognostic-Related Biomarker in OV Correlating with Immune Infiltrates

Pharmacogenomics and Personalized Medicine, 2023
Qian Ma,1,* Lei Chang,2,* Wenwen Wang,2,* Lingyi Che,1 Xiaoqin Song,3 Gailing Li,2 Ying Zhang,2 Yibing Chen,1 Zhuoyu Gu,4 Xin Ge5 1Genetics and Prenatal Diagnosis Center, First Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052 ...
Ma Q, Chang L, Wang W, Che L, Song X, Li G, Zhang Y, Chen Y, Gu Z, Ge X   +9 more
doaj   +3 more sources

Isoforms of leucyl-aminopeptidase of Cerambyx cerdo (Coleoptera, Cerambycidae) larvae [PDF]

Archives of Biological Sciences, 2004
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Božić Nataša M., Vujčić Zoran M., Nenadović Vera A., Ivanović J.   +3 more
doaj   +5 more sources

New role for leucyl aminopeptidase in glutathione turnover. [PDF]

Biochem J, 2004
A manganese-dependent cysteinyl-glycine hydrolysing activity has been purified to electrophoretic homogeneity from bovine lens. The characterization of the purified enzyme (molecular mass of the native protein, molecular mass of the subunit and extensive primary structure analysis) allowed the unequivocal attribution of the cysteinyl-glycine ...
Cappiello M, Lazzarotti A, Buono F, Scaloni A, D'Ambrosio C, Amodeo P, Méndez BL, Pelosi P, Del Corso A, Mura U.   +9 more
europepmc   +7 more sources

Clathrins Are Involved in the Endocytosis of Host Cytosol in the Malaria Parasite. [PDF]

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This study characterized clathrin function in hemoglobin uptake from host red blood cells via the malaria parasite's specific endocytosis machinery, cytostome. Clathrin heavy chain, clathrin light chain, and AP‐1 γ subunit were found associated with certain proteins known to be involved in cytostome function, and they were localized at the collars of ...
Miao J, Lucky AB, Ning G, Xia X, Liang X, Siddiqui F, Min H, Wang C, Li X, Zhou ZH, Cui L.   +10 more
europepmc   +2 more sources

KBE009: A Bestatin-Like Inhibitor of the Trypanosoma cruzi Acidic M17 Aminopeptidase with In Vitro Anti-Trypanosomal Activity

Life, 2021
Chagas disease, caused by the kinetoplastid parasite Trypanosoma cruzi, is a human tropical illness mainly present in Latin America. The therapies available against this disease are far from ideal. Proteases from pathogenic protozoan have been considered
Jorge González-Bacerio, Irina Arocha, Mirtha Elisa Aguado, Yanira Méndez, Sabrina Marsiccobetre, Maikel Izquierdo, Daniel G. Rivera, Katherine Figarella, Néstor L. Uzcátegui   +8 more
doaj   +1 more source

Identification and Validation of Compounds Targeting <i>Leishmania major</i> Leucyl-Aminopeptidase M17. [PDF]

ACS Infect Dis
داء الليشمانيات هو مرض استوائي مهمل ؛ لا يوجد حاليًا لقاح ويعتمد العلاج على حفنة من الأدوية التي تعاني من مشاكل متعددة بما في ذلك السمية والمقاومة. هناك حاجة ماسة لتطوير علاجات جديدة مناسبة للغرض، مع تقليل السمية واستهداف آليات جديدة للتغلب على المقاومة.
Aguado ME, Carvalho S, Valdés-Tresanco ME, Lin, Padilla-Mejia N, Corpas-Lopez V, Tesařová M, Lukeš J, Gray D, González-Bacerio J, Wyllie S, Field MC.   +11 more
europepmc   +5 more sources

Molecular characterization of a puromycin‐insensitive leucyl‐specific aminopeptidase, PILS‐AP [PDF]

European Journal of Biochemistry, 2000
The family M1 of Zn‐dependent aminopeptidases comprises members of closely related enzymes which are known to be involved in a variety of physiologically important processes. On the basis of two highly conserved peptide motifs, we have identified a new member of this family by PCR amplification and cDNA‐library screening.
L, Schomburg, H, Kollmus, S, Friedrichsen, K, Bauer   +3 more
  +7 more sources

Salt Priming as a Smart Approach to Mitigate Salt Stress in Faba Bean (Vicia faba L.)

Plants, 2022
The present investigation aims to highlight the role of salt priming in mitigating salt stress on faba bean. In the absence of priming, the results reflected an increase in H2O2 generation and lipid peroxidation in plants subjected to 200 mM salt shock ...
Amira K. Nasrallah, Mohamed A. M. Atia, Reem M. Abd El-Maksoud, Maimona A. Kord, Ahmed S. Fouad   +4 more
doaj   +1 more source