Results 31 to 40 of about 1,755 (134)

An approach to malignant mammary phyllodes tumors detection [PDF]

open access: yesVojnosanitetski Pregled, 2009
Background/Aim. Mammary phyllodes tumors (MPT) are uncommon fibroepithelial (biphasic) neoplasms whose clinical behavior is difficult to predict on the basis of histological criteria only.
Ilić Ivan   +6 more
doaj   +1 more source

Antioxidants, lysosomes and elements status during the life cycle of sea trout Salmo trutta m. trutta L.

open access: yesScientific Reports, 2021
The aim of our study was to elucidate the effects of both development stages (parr, smolt, adult, spawner), and kelt as a survival form and sex (male, female) on the functional stability of the lysosomal complex, biomarkers of oxidative stress, and ...
Natalia Kurhaluk, Halyna Tkachenko
doaj   +1 more source

Time-dependent changes in oxidative stress biomarkers and activities of lysosomal and antioxidant enzymes in hepatic tissue of rainbow trout (Oncorhynchus mykiss Walbaum) following vaccination against Yersinia ruckeri

open access: yesFisheries & Aquatic Life, 2023
This study analyzed time-dependent effects of vaccination against Y. ruckeri on the oxidative mechanism underlying those effects by detecting relevant lipid peroxidation (2-thiobarbituric acid reactive substances, TBARS) and protein oxidation biomarkers [
Tkaczenko Halina   +4 more
doaj   +1 more source

Cloning and Characterization of a Leucyl Aminopeptidase from Three Pathogenic Leishmania Species [PDF]

open access: yesJournal of Biological Chemistry, 2002
Aminopeptidases are emerging as exciting novel drug targets and vaccine candidates in parasitic infections. In this study, we describe for the first time an aminopeptidase from three highly pathogenic Leishmania species. Intronless genes encoding a leucyl aminopeptidase (lap) were cloned from Leishmania amazonensis, Leishmania donovani, and Leishmania ...
Rory E, Morty, Jennifer, Morehead
openaire   +2 more sources

Characterization of serum and tissue oxytocinase and tissue oxytocin in the pregnant and non-pregnant mare

open access: yesScientific Reports, 2023
Oxytocin is a hormone with functions in: reproduction, maternal bonding, milk ejection, and feeding/social behavior, and is reported to be present in a variety of tissues. Our goal is to characterize oxytocin and leucyl and cystinyl aminopeptidase (LNPEP/
Mariana Diel de Amorim   +7 more
doaj   +1 more source

Determination of the species among mitis group of genus Streptococus using a molecular identification key [PDF]

open access: yesZbornik Matice Srpske za Prirodne Nauke, 2012
We analyzed the gene order conservation among the species of genus Streptococcus and based on this we developed a molecular identification key. The identification key was not made up based on the genes’ amino acid or nucleotide sequences but on the ...
Kanjo Ištvan L.
doaj   +1 more source

TrpM, a Small Protein Modulating Tryptophan Biosynthesis and Morpho-Physiological Differentiation in Streptomyces coelicolor A3(2). [PDF]

open access: yesPLoS ONE, 2016
In the model actinomycete Streptomyces coelicolor A3(2), small open reading frames encoding proteins with unknown functions were identified in several amino acid biosynthetic gene operons, such as SCO2038 (trpX) in the tryptophan trpCXBA locus.
Emilia Palazzotto   +9 more
doaj   +1 more source

A Modular and Customizable CRISPR/Cas Toolkit for Epigenome Editing of Cis‐regulatory Modules

open access: yesAdvanced Science, Volume 12, Issue 47, December 18, 2025.
Epigenome editing surpasses genome editing in gene regulation. Modular epigenome editing frameworks are developed to interrogate cis‐regulome, enabling tunable reprogramming of cis‐elements, uncovering their epigenetic responsiveness and cross‐species portability.
Lingrui Zhang   +6 more
wiley   +1 more source

Effects of melatonin and metformin in preventing lysosome-induced autophagy and oxidative stress in rat models of carcinogenesis and the impact of high-fat diet

open access: yesScientific Reports, 2022
Imbalanced glucose tolerance and insulin resistance remain important as high cancer risk factors. Metformin administration to diabetic patients may be associated with a reduced risk of malignancy.
Natalia Kurhaluk, Halyna Tkachenko
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +31 more
wiley   +1 more source

Home - About - Disclaimer - Privacy