Results 11 to 20 of about 2,220 (157)

The NFIA::CBFA2T3 identifies a molecularly defined subgroup of acute erythroid leukemia/erythroid sarcoma [PDF]

Frontiers in Oncology
IntroductionThe World Health Organization classification of tumors of hematopoietic and lymphoid tissues recognizes acute erythroid leukemia as a distinct entity under myeloid neoplasms.
Marta Brunetti, Kristin Andersen, Geir Erland Tjønnfjord, Geir Erland Tjønnfjord, Geir Erland Tjønnfjord, Bernward Zeller, Signe Spetalen, Signe Spetalen, Monica Cheng Munthe-Kaas, Liv Toril Nygård Osnes, Tina Treu Os, Francesca Micci   +11 more
doaj   +2 more sources

Frequent NPM1 mutation, monoblastic/monocytic origin and prognostic significance of organ and system involvement in myeloid sarcoma: a multicenter study. [PDF]

J Pathol Clin Res
Abstract Myeloid sarcoma (MS) is a tumorous extramedullary proliferation of blast or blast equivalent cells (e.g., promonocytes or promyelocytes). The most frequent cutaneous presentation is often referred to as leukemia cutis (LC). These lesions, especially without the clinical context of a known bone marrow disease, pose a differential diagnostic ...
Jenei A, Kajtár B, László T, Juratli HA, Vida L, Szepesi Á, Mózes R, Timár B, Halter J, Dirnhofer S, Tzankov A.   +10 more
europepmc   +2 more sources

Phenotypes of blasts in acute erythroblastic and megakaryoblastic leukemia - Review.

The Keio Journal of Medicine, 1987
J. Breton-Gorius
openaire   +4 more sources

Could Old-School Erythroleukaemia be Back in Style Thanks to <i>TP53</i>? [PDF]

EJHaem
eJHaem, Volume 6, Issue 4, August 2025.
Rieu JB, Canali A, Comont T, Ousset L, De Mas V.   +4 more
europepmc   +2 more sources

Masking as Myelofibrosis: A Case of Tp53 Mutated Acute Erythroid Leukemia Presenting With Pancytopenia and Bone Pain. [PDF]

Case Rep Hematol
Acute erythroid leukemia is a rare form of acute myeloid leukemia, comprising only 1% of myelogenous leukemia diagnoses. Presentations can vary and given its aggressive nature, prompt investigation and appropriate treatment are needed when suspicions arise. Here, we discuss a case of a 54‐year‐old male who initially presented with worsening fatigue and
Parker K, Cutrer RC.
europepmc   +2 more sources

Erythropoiesis in health and disease: Distinguishing defective and ineffective erythropoiesis. [PDF]

Hemasphere
Abstract Erythropoiesis is a finely regulated process ensuring continuous red blood cell production to maintain oxygen delivery. Disruptions in this process give rise to defective erythropoiesis, characterized by impaired lineage commitment and progenitor development, and ineffective erythropoiesis (IE), marked by expansion of erythroid progenitors ...
El Hoss S, Lizarralde-Iragorri MA, Maciel TT, Hermine O.   +3 more
europepmc   +2 more sources

Loss of erythroblasts in acute myeloid leukemia causes iron redistribution with clinical implications [PDF]

Blood Advances, 2020
Abstract Acute myeloid leukemia (AML) is a heterogeneous disease with poor prognosis and limited treatment strategies. Determining the role of cell-extrinsic regulators of leukemic cells is vital to gain clinical insights into the biology of AML.
Marta Lopes, Tiago L. Duarte, Maria J. Teles, Laura Mosteo, Sérgio Chacim, Eliana Aguiar, Joana Pereira-Reis, Mónica Oliveira, André M. N. Silva, Nuno Gonçalves, Gabriela Martins, Isabella Y. Kong, Magnus Zethoven, Stephin Vervoort, Sandra Martins, Miguel Quintela, Edwin D Hawkins, Fernanda Trigo, João T. Guimarães, José M. Mariz, Graça Porto, Delfim Duarte   +21 more
openaire   +3 more sources

Clinical, morphologic, and cytogenetic characteristics of 26 patients with acute erythroblastic leukemia [PDF]

Blood, 1992
Abstract We have performed a retrospective analysis of the clinical, morphologic, and cytogenetic findings in 26 patients diagnosed between January 1969 and September 1991 with acute erythroblastic leukemia de novo (EL or AML-M6). Clonal chromosomal abnormalities were found in 20 (77%) patients (95% confidence interval [CI], 61% to 93%).
O I, Olopade, M, Thangavelu, R A, Larson, R, Mick, A, Kowal-Vern, H R, Schumacher, M M, Le Beau, J W, Vardiman, J D, Rowley   +8 more
openaire   +3 more sources

Biochemical Abnormality of DNA Synthesis of Erythroblasts in Acute and Chronic Myeloid Leukemia [PDF]

Blood, 1973
Abstract Six patients with acute and chronic myeloid leukemia (AML and CML) showed a low incorporation of labeled DNA precursors into basophilic erythroblasts. Based on mitotic indices and the use of vincristine as a stathmokinetic tool, it was evident that brisk proliferation in this cell compartment took place.
P, Ernst, M, Baccarani, S A, Killmann
openaire   +2 more sources

Acute erythroid leukemia: autopsy report of a rare disease

Autopsy and Case Reports, 2011
Acute erythroid leukemia (AEL) is a rare subtype of acute myeloid leukemia (AML), characterized by predominant erythroid proliferation. The 2008 World Health Organization (WHO) classification of AML defined two AEL subtypes: erythroleukaemia (EL), in ...
Cristiane Rúbia Ferreira, Fabiana Roberto Lima, Edna Harumi Goto, Elizabeth In Myung Kim, Luciana Andréa Avena Smeili, Fernando Peixoto Ferraz de Campos, Maria Claudia Nogueira Zerbini   +6 more
doaj   +1 more source