Results 31 to 40 of about 43,548 (209)

Treatment advances have not improved the early death rate in acute promyelocytic leukemia

Haematologica, 2012
Early mortality in acute promyelocytic leukemia has been reported to occur in less than 10% of patients treated in clinical trials. This study reports the incidence and clinical features of acute promyelocytic leukemia patients treated at Stanford ...
James Scott McClellan, Holbrook E. Kohrt, Steven Coutre, Jason R. Gotlib, Ravindra Majeti, Ash A. Alizadeh, Bruno C. Medeiros   +6 more
doaj   +1 more source

Preferential expression of the transcription coactivator HTIF1alpha gene in acute myeloid leukemia and MDS-related AML [PDF]

, 2002
HTIF1α, a transcription coactivator which is able to mediate RARα activity and functionally interact with PML, is encoded by a gene on chromosome 7q32–34, which is a critical region in acute myeloid leukemias (AML). With the assumption that this gene may
AGUIARI, Gianluca, CASTOLDI, GL, CUNEO, Antonio, DE ANGELI, C, DEL SENNO, Laura, GANDINI, D, LANZA, F, MANZATI, E, PANDOLFI, PP   +8 more
core   +1 more source

A giant thrombus in the right atrium of a patient with acute promyelocytic leukemia M3

Radiology Case Reports, 2023
Acute promyelocytic leukemia is a special type of acute myeloid leukemia. Patients with this disease are at high risk of complications. Right atrial thrombosis is a rare but potentially serious complication.
Pham Ngoc Thach, MD, Ho Tran Ban, MD, Huynh-Thi Vu Quynh, MD, Tran-Thi Thanh, MD, Phan Thao Nguyen, MD, Trinh Nguyen Ha Vi, MD, Tran Ba Hieu, MD, Nguyen Duc Chinh, MD, Tran Hoa, MD, Bui The Dung, MD, Nguyen Minh Duc, MD   +10 more
doaj   +1 more source

FLT3 Length Mutations as Marker for Follow-Up Studies in Acute Myeloid Leukaemia [PDF]

, 2004
Length mutations within the FLT3 gene (FLT3-LM) can be found in 23% of acute myeloid leukaemia (AML) and thus are the most frequent mutations in AML. FLT3-LM are highly correlated with AML with normal karyotype and other cytogenetic aberrations of the ...
Haferlach, Torsten, Hiddemann, Wolfgang, Kern, Wolfgang, Schnittger, Susanne, Schoch, Claudia   +4 more
core   +1 more source

PML isoforms in response to arsenic: high-resolution analysis of PML body structure and degradation [PDF]

, 2014
Arsenic is a clinically effective treatment for acute promyelocytic leukaemia (APL) in which the promyelocytic leukaemia (PML) protein is fused to retinoic receptor alpha (RARα).
Beech, Bernardi, Boisvert, Brand, Condemine, Condemine, Cuchet, Cuchet-Lourenço, de Thé, Fogal, Geng, Geoffroy, Hattersley, Hu, Ishov, Jeanne, Jensen, Jul-Larsen, Kamitani, Koken, Lallemand-Breitenbach, Lallemand-Breitenbach, Lallemand-Breitenbach, Lang, Lång, Maroui, Mathews, Negorev, Powell, Tatham, Weidtkamp-Peters, Weisshaar, Xu, Yu, Zhu   +34 more
core   +4 more sources

Detection of monosomy 7 in interphase cells of patients with myeloid disorders [PDF]

, 1990
Six patients, five with acute myeloid leukemia (AML) and one with a myelodysplastic syndrome (MDS), were found to have monosomy 7 by conventional cytogenetics at diagnosis.
Cremer, Thomas, Gezer, Sefer, Kolluri, Rukmini V., Manuelidis, L., Raza, Azra, Sait, Sheila   +5 more
core   +1 more source

Arsenic trioxide downregulates cancer procoagulant activity in MCF-7 and WM-115 cell lines in vitro [PDF]

, 2015
© 2015 Termedia Sp. z o. o. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing ...
Gizelska, Katarzyna, Hoffman, Ewelina A, Mielicki, Wojciech, Mirowski, Marek   +3 more
core   +2 more sources

Acute myeloid leukemia with fusion resembling acute promyelocytic leukemia, initially presenting as sweet syndrome: A case report and literature review

Journal of International Medical Research
Some subtypes of acute myeloid leukemia share morphologic, immunophenotypic, and clinical features of acute promyelocytic leukemia but lack a promyelocytic leukemia–retinoic acid receptor alpha fusion gene.
Huan Liu, Guo-Xia Liu, Feng-Hai Liu, Shu-Guo Wang   +3 more
doaj   +1 more source

Relapsed acute promyelocytic leukemia in a hemodialysis-dependent patient treated with arsenic trioxide: a case report

Journal of Medical Case Reports, 2012
Introduction In the relapsed setting, arsenic trioxide remains the backbone of treatment. Scant literature exists regarding treatment of relapsed acute promyelocytic leukemia in patients with renal failure.
Emmons Gregory S, Steingart Richard H, Stewart James A, Mertens Wilson C   +3 more
doaj   +1 more source

Case report: A rare case of acute myeloid leukemia with CPSF6–RARG fusion resembling acute promyelocytic leukemia

Frontiers in Oncology, 2022
Retinoic acid receptor gamma (RARG) gene rearrangement has been reported in several acute myeloid leukemia (AML) patients. They resemble classical acute promyelocytic leukemia (APL) patients in clinical features, morphology, and immunophenotype but do ...
Junmei Zhao, Wentao Wang, Li Yan, Xi Chen, Wen Li, Wanying Li, Tingting Chen, Lunhua Chen   +7 more
doaj   +1 more source