Results 21 to 30 of about 4,796,691 (248)

Leukemia Inhibitory Factor Induces Proopiomelanocortin via CRH/CRHR Pathway in Mouse Trophoblast

Frontiers in Cell and Developmental Biology, 2021
We previously showed that maternal leukemia inhibitory factor (LIF) induces placental production of adrenocorticotropic hormone (ACTH), which stimulates fetal nucleated red blood cells to further secrete LIF and promote neurogenesis in rodent brains ...
He Wang, He Wang, Hiromi Sakata-Haga, Hiroko Masuta, Mitsuhiro Tomosugi, Tsuyoshi Tsukada, Hiroki Shimada, Daisuke Sakai, Hiroki Shoji, Toshihisa Hatta   +9 more
doaj   +1 more source

LIFR (leukemia inhibitory factor receptor alpha) [PDF]

, 2010
Review on LIFR (leukemia inhibitory factor receptor alpha), with data on DNA, on the protein encoded, and where the gene is ...
V Cormier-Daire, Dagoneau, N, Cormier-Daire, V, N Dagoneau   +3 more
core   +1 more source

Identification of cooperating genetic events in acute leukemia [PDF]

, 2009
The genetic alterations associated with acute leukemia can be divided into two functional groups. The class I mutations enhance cellular proliferation and survival by constitutive activation of mainly protein tyrosine kinases signaling pathways.
Liu, Ting
core   +1 more source

Genome-wide identification and analysis of mRNA expression in fibroblasts, ES cells, and iPS cells

Genomics Data, 2016
Genome-wide expression patterns of mRNA were compared between mouse embryonic fibroblasts (MEFs), embryonic stem cells (ESCs), and various types of induced pluripotent stem cells (iPSCs).
Hiroyuki Hirai, Nobuaki Kikyo
doaj   +1 more source

Functional characterization of the Plasmodium falciparum and P-berghei homologues of macrophage migration inhibitory factor [PDF]

, 2007
Macrophage migration inhibitory factor (MIF) is a mammalian cytokine that participates in innate and adaptive immune responses. Homologues of mammalian MIF have been discovered in parasite species infecting mammalian hosts (nematodes and malaria ...
Sarah E. Reece, Pain, Arnab, Robert Kleemann, Kooistra, Teake, Augustijn, Kevin D., Reece, Sarah E., Thompson, Joanne, Siebum, Arjan H. G., Joanne Thompson, Kevin D. Augustijn, Waters, Andrew P., Arjan H. G. Siebum, Kleemann, Robert, Arnab Pain, Janse, Chris J., Chris J. Janse, Teake Kooistra, Carina E. Crawford, Crawford, Carina E., Andrew P Waters   +19 more
core   +1 more source

Changes in LIF expression on PCOS as biomarker implantation

Majalah Obstetri dan Ginekologi, 2021
Objectives: This study aimed to compare the endometrial expression of LIF PCOS compared to normal and determine the effect of PCOS and external variables that affect LIF expression.
Uki Retno Budihastuti, Eriana Melinawati, Sri Sulistyowati, Tanti Arianti   +3 more
doaj   +1 more source

Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF). Potential role in asthma [PDF]

, 1998
Macrophage migration inhibitory factor (MIF) is a potent proinflammatory mediator that has been shown to potentiate lethal endotoxemia and to play a potentially important regulatory role in human acute respiratory distress syndrome (ARDS).
N Hirani, S C Donnelly, Bucala, R, Donnelly, Seamas C, A P Greening, A G Rossi, Rossi, Adriano G, Hirani, N, C Haslett, I Rahman, R Bucala, Metz, C N, C N Metz, Rahman, I, Haslett, Christopher, Greening, A. P.   +15 more
core   +1 more source

Constitutive cytoplasmic localization of p21Waf1/Cip1 affects the apoptotic process in monocytic leukaemia [PDF]

, 2003
In the present study, we analysed the expression and localization of p21Waf1/Cip1 in normal and malignant haematopoietic cells. We demonstrate that in normal monocytic cells, protein kinase C (PKC)-induced p21 gene activation, which is nuclear factor-κB (
Eggen, BJL, Vellenga, E, Eggen, B.J.L.,, Eggen, BJL; id_orcid, Schepers, H.,, Vellenga, E.,, Schepers, H, Geugien, M.,, Geugien, M   +8 more
core   +2 more sources

A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

Nature Communications, 2021
Leukemia inhibitory factor receptor (LIFR) is frequently downregulated in liver cancer. Here the authors show that loss of LIFR promotes liver tumorigenesis and confers resistance to drug-induced ferroptosis through NF-κB-mediated upregulation of iron ...
Fan Yao, Yalan Deng, Yang Zhao, Ying Mei, Yilei Zhang, Xiaoguang Liu, Consuelo Martinez, Xiaohua Su, Roberto R. Rosato, Hongqi Teng, Qinglei Hang, Shannon Yap, Dahu Chen, Yumeng Wang, Mei-Ju May Chen, Mutian Zhang, Han Liang, Dong Xie, Xin Chen, Hao Zhu, Jenny C. Chang, M. James You, Yutong Sun, Boyi Gan, Li Ma   +24 more
doaj   +1 more source

Possible Role of Leukemia Inhibitory Factor and Inflammatory Cytokines in The Recurrent Spontaneous Abortion: A Case-Control Study [PDF]

International Journal of Fertility and Sterility, 2023
Background: Despite of long-lasting efforts, in more than 50% of cases, the etiology of recurrent spontaneous abortion (RSA) remains unknown. Leukemia inhibitory factor (LIF) has an essential role in the reproductive process, such as modulating ...
Seyed Mohsen Miresmaeili, Farzaneh Fesahat, Negar Kazemi, Hossein Ansariniya, Fateme Zare   +4 more
doaj   +1 more source