Effect of Irisin on LIF and integrin αvβ3 in rats of implantation failure
Reproductive Biology and Endocrinology, 2021 Objective The aim of this study is to investigate the effect of irisin on leukemia inhibitory factor (LIF) and integrin αvβ3 in implantation failure uterus.
Li Zhou +3 more
doaj +1 more source
Leukemia Inhibitory Factor Enhances Endogenous Cardiomyocyte Regeneration after Myocardial Infarction. [PDF]
PLoS ONE, 2016 Cardiac stem cells or precursor cells regenerate cardiomyocytes; however, the mechanism underlying this effect remains unclear. We generated CreLacZ mice in which more than 99.9% of the cardiomyocytes in the left ventricular field were positive for 5 ...
Masato Kanda +10 more
doaj +1 more source
Comparative study of gp130 cytokine effects on corticotroph AtT-20 cells - Redundancy or specificity of neuroimmunoendocrine modulators? [PDF]
, 2004 Objective: This comparative in vitro study examined the effects of all known gp130 cytokines on murine corticotroph AtT-20 cell function. Methods: Cytokines were tested at equimolar concentrations from 0.078 to 10 nM.
Kopp, F. B. +9 more
core +1 more source
Leukemia Inhibitory Factor Induces Proopiomelanocortin via CRH/CRHR Pathway in Mouse Trophoblast
Frontiers in Cell and Developmental Biology, 2021 We previously showed that maternal leukemia inhibitory factor (LIF) induces placental production of adrenocorticotropic hormone (ACTH), which stimulates fetal nucleated red blood cells to further secrete LIF and promote neurogenesis in rodent brains ...
He Wang +9 more
doaj +1 more source
LIFR (leukemia inhibitory factor receptor alpha) [PDF]
, 2010 Review on LIFR (leukemia inhibitory factor receptor alpha), with data on DNA, on the protein encoded, and where the gene is ...
V Cormier-Daire +3 more
core +1 more source
Genome-wide identification and analysis of mRNA expression in fibroblasts, ES cells, and iPS cells
Genomics Data, 2016 Genome-wide expression patterns of mRNA were compared between mouse embryonic fibroblasts (MEFs), embryonic stem cells (ESCs), and various types of induced pluripotent stem cells (iPSCs).
Hiroyuki Hirai, Nobuaki Kikyo
doaj +1 more source
Identification of cooperating genetic events in acute leukemia [PDF]
, 2009 The genetic alterations associated with acute leukemia can be divided into two functional groups. The class I mutations enhance cellular proliferation and survival by constitutive activation of mainly protein tyrosine kinases signaling pathways.
Liu, Ting
core +1 more source
Changes in LIF expression on PCOS as biomarker implantation
Majalah Obstetri dan Ginekologi, 2021 Objectives: This study aimed to compare the endometrial expression of LIF PCOS compared to normal and determine the effect of PCOS and external variables that affect LIF expression.
Uki Retno Budihastuti +3 more
doaj +1 more source
Constitutive cytoplasmic localization of p21Waf1/Cip1 affects the apoptotic process in monocytic leukaemia [PDF]
, 2003 In the present study, we analysed the expression and localization of p21Waf1/Cip1 in normal and malignant haematopoietic cells. We demonstrate that in normal monocytic cells, protein kinase C (PKC)-induced p21 gene activation, which is nuclear factor-κB (
Eggen, BJL +8 more
core +1 more source
A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
Nature Communications, 2021 Leukemia inhibitory factor receptor (LIFR) is frequently downregulated in liver cancer. Here the authors show that loss of LIFR promotes liver tumorigenesis and confers resistance to drug-induced ferroptosis through NF-κB-mediated upregulation of iron ...
Fan Yao +24 more
doaj +1 more source